Publications

2006

Simmgen M., Knauf C., Lopez M., Choudhury A.I., Charalambous M., Cantley J., Bedford D.C., Claret M., Iglesias M.A., Heffron H., Cani P.D., Vidal-Puig A., Burcelin R., Withers D.J. Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice. Diabetologia 49: 552-561, 2006. IF: 5.337. DOI 10.1007/s00125-005-0084-4

Ansiaux R., Baudelet C., Cron G.O., Segers J., Dessy C., Martinive P., De Wever J., Verrax J., Wauthier V., Beghein N., Gregoire V., Buc Calderon P., Feron O., Gallez B. Botulinum toxin potentiates cancer radiotherapy and chemotherapy. Clin. Cancer Res: 12 (4), 2006. IF : 5.715

Vanhulle V.P., Neyrinck A.M., Pycke J.M., Horsmans Y., Delzenne A.M. Role of apoptotic signalling pathway in metabolic disturbances occurring in liver tissue after cryopreservation: Study on rat precision-cut liver slices. Life Sciences 78, 1570-1577, 2006. IF 2.512

CANI PD., KNAUF C., IGLESIAS MA, DRUCKER DJ, DELZENNE AM, BURCELIN R. Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor. Diabetes,,(IF: 8.9) 55 :1484-1490, 2006. IF 8.9

Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iglesias MA, Pillot B, Bado A., Tronche F; Mitghieux G, Vaulont S, Burcelin R. and Viollet B. Liver adenosine monophosphate-activated kinase-a2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology 147 (5): 2432-2441, 2006. IF: 5.313

Cani PD, Joly E., Horsmans Y and Delzenne NM. Oligofructose promotes satiety in healthy human : a pilot study. European Journal of Clinical Nutrition 60: 567-572, 2006. IF 2.163

Verrax J., Bollen S., Delvaux M., Taper H., Buc Calderon P. New insights about the potential application of the association of vitamins C (sodium ascorbate) and K3 (Menadione) as auxiliary therapy incancer treatment. Medicinal Chemistry Reviews, 2, 277-282, 2005. IF ?

Delmée E., Cani PD, Gual H., Knauf C, Burcelin R, Maton N, Delzenne NM. Relation between colonic proglucagose in high fat diet-fed mice. Life Sciences 79: 1007-1013, 2006. IF: 52.512

Verrax J., Stockis J., Tison A., Taper HS., Buc Calderon P. Oxidative tress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumor growth in nude mice. Biochemical Pharmacology 72:671-680, 2006 IF: 3.617

Lesniewska V., Rowland I, Cani PD, Neyrinck AM, Delzenne NM, Naughton PJ. Effect on components of the intestinal microflora and plasma neuropeptide levels of feeding lactobacillus delbrueckii, bifidobacterium lactis, and inulin to adult and elderly rats. Applied and Environmental Microbiology, 72 (10): 6533-6538, 2006. IF: 3.818

Wauthier V., Verbeeck RK., Buc Calderon P. Decreased CYP3A2 expression and activity in senescent male Wistar rats: Is there a role for HNF4)a? Experimental Gerontology, 41: 846-854, 2006. IF: 3.008

Wauthier V., Schenten V., Verbeeck RK., Buc Calderon P. Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats. Life Sciences, 79: 1913-1920, 2006. IF: 2.512.

2007

Marques C., D’auria L., Cani PD., Baccelli C., Rozenberg R., Ruibal-Mendieta NL, Petitjean G., Delacroix DL., Quetin-Leclercq J., Habib-Jiwan JL., Meurens M., Delzenne NM. Comparison of glycemic index of spelt and wheat bread in human volunteers. Food Chemistry, 100, 1265-1271, 2007.

Verrax J., Vanbever S., Stockis J., Taper H., Buc Calderon P. Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells. Int. J. Cancer: 120,1192-1197, 2007.

Wauthier V., Dubois P., Verbeeck RK., Buc Calderon P. Induction of CYP2C12 expression in senescent male rats is well correlated to an increase of HNF3b expression, while the decline of CYP2C11 expression is unlikely due to a decrease of STAT5 activation. Biochemical Pharmacology, 73, 923-933, 2007.

Wauthier V., Verbeeck R.K., and Buc Calderon P. The effect of ageing on cytochrome P450 enzymes: consequences for drug biotransformation in the elderly. Current Medicinal Chemistry, 14, 745-757, 2007.

Cani P.D., Hoste S., Guiot Y., and Delzenne N. Dietary non-digestible carbohydrates promote L-cell differenciation in the proximal colon of rats. British Journal of Nutrition: 98, 32-37, 2007.

Cani P.D., Holst J.J., Drucker D.J., Delzenne N.M., Thorens B., Burcelin R., and Knauf C. GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Molecular and Cellular Endrocrinology, 276, 18-23, 2007.

Cani P.D., Knauf C., and Burcelin R. Les analogues du GLP-1. Le point et leurs caractéristiques. Diabète & Obésité, vol. 2, n°5, Janv 2007.

Kallin A., Johannessen L. E., Cani, P.D., Marbehant C.Y., Essaghir A., Foufelle F., Ferré P., Heldin C.H., Delzenne N.M., and Demoulin J.B. SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55gg. Journal of Lipid Research, 48, 1628-1636, 2007

Cani P.D., Amar J., Iglesias M.A., Poggi A., Knauf C., Bastelica D., Neyrinck A.M., Fava F., Tuohy K.M., Chabo, C., Waget A., Delmée E., Cousin B., Sulpice T., Chamontin B., Ferrières J., Tanti J.F., Gibson G.R., Casteilla L., Delzenne N.M., Alessi M.C and Burcelin R., Metabolic Endoxemia initiates obesity and insulin resistance. Diabetes, Vol. 56, 1761-1772, 2007.

Baririan N., Van Obbergh L., Desager J.P., Verbeek R.K., Wallemacq P., Starkel P. and Horsmans Y. Alfentanil-induced miosis as a surrogate measure of Alfentanil pharmacokinetics in patients with mild and moderate liver cirrhosis. Clin. Pharmacokinet., 46 (3): 261-270, 2007.

+Chapitre 7 Nathalie

Cuesta de Juan S., Monte M.J., Macias R.I.R., Wauthier V., Buc Calderon P. and Marin J.J.G. Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis. Journal of Lipid Research, 48:132-?, 2007.

Delzenne N.M., Cani P.D., Delmée E. and Neyrinck A.M. Non-digestible oligosaccharides. Chapitre 7 dans Novel food ingredients for weight control.  Edited by C.J.K. Henry CRC Press Boca Raton Boston New York Washington, DC.

Neyrinck A.M., Mouson A., Delzenne N.M. Dietary supplementation with laminarin, a fermentable marine b (1-3) glucan, protects against hepatotoxicity induced by LPS in rat by modulating immune response in the hepatic tissue. International Immunopharmacology 7: 1497-1506, 2007.

Cani P.D., Neyrinck A.M., Fava F., Knauf C., Burcelin R.G., Tuohy K.M., Gibson G.R., Delzenne N.M. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia, 50: 2374-2383, 2007.

Burcelin R., Cani P.D., and Knauf C. Glucagon-Like peptide-1 and energy homeostasis^1-3. The Journal of Nutrition2534S-2538S, 2007.

Delzenne N.M., Cani P.D., and Neyrinck A.M. Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data^1-5. The Journal of Nutrition 2547S-2551S, 2007.

Pospisilik J.A., Knauf C., Joza N., Benit P., Orthofer M., Cani P.D., Eberserger I., Nakashima T., Sarao R., Neely G., Esterbauer H., Kozlov A., Hahn C.R., Kroemer G., Rustin P., Burcelin R., and J.M. Penninger. Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell, 131: 1-16, 2007.

Cani P.D., and Delzenne N.M. Gut microflora as a target for energy and metabolic homeostasis. Current Opinion in Clinical Nutrition and Metabolic Care, 10: 729-734, 2007.

Cabou C., Cani P.D., Campistron G., Knauf C., Mathieu C., Sartori C., Amar J., Scherrer U. and Burcelin R. Central insulin regulates heart rate and arterial blood flow. Diabetes, 56: 2872-2877, 2007.

2008

Benites J., Rojo L., Valderrama J.A., Taper H., Buc Calderon P. Part 1: Effect of vitamin C on the biological activity of two euryfurylbenzoquinones on TLT, a murine hepatoma cell line. European Journal of Medicinal Chemistry, doi:10.1016/j.ejmech.2007.11.015

Poncin S., Gérard A.-C., Boucquey M., Senou M., Buc Calderon P., Knoops B., Lengelé B., Many M.-C., and Colin I.M. Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content. Endocrinology, 149:424-433, 2007    doi:10.12/en.2007-0951

Verrax J., Taper H., and Buc Calderon P. Targeting cancer cells by an oxidant-based therapy. Current Molecular Pharmacology, 2008, 1,80-92.

Urias-Silvas J.E., Cani P.D., Delmée E., Neyrinck A.M., Lopez M.G., and Delzenne N.M. Physiological effects of dietary fructans extracted from agave tequilana Gto. And dasylirion spp. British Journal of Nutrition, 2008, 99: 254-261.

Membrez M., Blancher F., Jaquet M., Bibiloni R., Cani P.D., Burcelin R.G.,Corthesy I., Macé K., and Chou C.J. Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. The FASEB Journal article fj.07-102723. Published online March 7, 2008.

Cani P.D., Delzenne N.M., Amar J., Burcelin R. Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding. Pathologie Biologie (2008) doi.10.1016/j.patbio.2007.09.008.

Amar J., Burcelin R., Ruidavets J-B., Cani P.D., Fauvel J., Alessi M-C., Chamontin B., and Ferrières J. Energy intake is associated with endotoxemia in apparently healthy men^1-4. Am J Clin Nutr 87: 1219-23, 2008.