Publications

PUBLICATIONS (SINCE 2000)

2011

  • WORONOFF G., EL HARRAK A., MAYOT E., SCHICKE O., MILLER O.J., SOUMILLION P., GRIFFITHS A.D., RYCKERLYNCK M. New Generation of Amino Coumarin Methyl Sulfonate-Based Fluorogenic Substrates for Amidase Assays in Droplet-Based Microfluidic Applications.  Anal Chem. 83 (2011), 2852-7
  • VOLKOV A.N., BARRIOS H., MATHONET P., EVRARD C., UBBINK M., DECLERCQ J.P., SOUMILLION P., FASTREZ J. Engineering allosteric regulation by aminoglycosides into TEM1-beta-lactamase. ChemBioChem, 12 (2011), 904-13
  • SOUMILLION P., BAUDOUX B., Method for extracellular production of recombinant biomolecules in a microorganism. Patent WO2011/141528 (A1), EP2386641 (A1), 2011

2010

  • MATHIEU V., FASTREZ J.? SOUMILLION P. Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 beta-lactamase. Protein Eng Des Sel., 23 (2010), 699-709.
  • DESCHUYTENEER G., GARCIA S., MICHIELS B., BAUDOUX B., DEGAND H., MORSOMME P., SOUMILLION P. Intein-mediated cyclization of randomized peptides in the periplasm of Escherichia coli and their extracellular secretion. ACS Chem Biol. 5 (2010), 691-700.
  • SHI Y.F., SOUMILLION P., UEDA M., Effects of catalytic site mutations on active expression of phage fused penicillin acylase. J Biotechnol. 145 (2010),139-42.
  • TRABELSI H., SOUMILLION P., Directed evolution of a DD-peptidase into a becta-lactamase. FEBS J. 277 (2010), 302

  • BAUDOUX B., SOUMILLION P., Genetic engineering of allosteric beta-lactamases. FEBS J. 277 (2010), 250

2009

  • ALSTEENS D., PESAVENTO E., CHEUVART G., DUPRES V., TRABELSI H., SOUMILLION P., DUFRENE Y.F. Controlled manipulation of bacteriophages using single-virus force spectroscopy. ACS Nano.3 (2009), 3063-8
  • BREYER D., HERMAN P., BRANDENBURGER A., GHEYSEN G., REMAUT E., SOUMILLION P., VAN DOORSSELAERE J., CUSTERS R., PAUWELS K., SNEYERS M., REHEUL D. Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge? Environ Biosafety Res. 8 (2009), 57-64
  • URBACH C.,  EVRARD C., PUDZAITIS V., FASTREZ J., SOUMILLION P., DECLERCQ J.P. Structure of PBP-A from Thermosynechococcus elongatus, a penicillin-binding protein closely related to class A beta-lactamases. J Mol Biol. 386 (2009), 109-20

2008

  • URBACH Carole, FASTREZ Jacques, SOUMILLION Patrice, A new family of cyanobacterial penicillin-binding proteins. A missing link in the evolution of class A beta-lactamases, J. Biol. Chem., 283, 2008, p. 32516-32526. 

2006

  • FERNANDEZ-GACIO A, CODINA-BARRIOS A, FASTREZ J, RIANT O, SOUMILLION P, Transforming carbonic anhydrase into epoxide synthase by metal exchange, ChemBioChem, 7, 2006, 1013-1016.
  • MATHONET P, BARRIOS-CAMACHO H, SOUMILLION P, FASTREZ J, Selection of allosteric beta-lactamase mutants featuring an activity regulation by transition metal ions, Protein Sci., 15, 2006, 2335-2343.
  • MATHONET P, DEHERVE J, SOUMILLION P, FASTREZ J, Active TEM-1 beta-lactamase mutants with random peptides inserted in three contiguous surface loops, Protein Sci., 15, 2006, 2323-2334.
  • BREDO A, MATHONET P, DESCHUYTENEER G, SOUMILLION P, Gene reconstitution using high efficency homologous recombination between a bacteriophage fd and a plasmid, J. Biotech., 126, 2006, 286-290.

2005

  • LEGENDRE D, FASTREZ J, Production in Saccharomyces cerevisiae of MS2 virus-like particles packaging functional heterologous mRNAs. . Journal of Biotechnology, 117(2), 183-194.

 2004

  • SOUMILLION P, LEGENDRE D, FASTREZ J, Chapter 17 : Enzyme engineering by phage display, In: Enzyme functionality, desing, engineering and screening, A. Svendsen ed., New York, USA, Marcel Dekker, 2004, 391-412.
  • SOUMILLION P, Chapter 6 : Selection of phage-displayed enzymes, In: Evolutionary methods in biotechnology, clever tricks for directed evolution, S. Brakmann & A. Schwienhorst ed., Weinheim, Germany, Wiley-VCH Verlag GmbH, 2004, 47-64.
  • EVRARD C, CAPRON A, MARCHAND C, CLIPPE A, WATTIEZ R, SOUMILLION P, KNOOPS B, DECLERCQ J-P, Crystal Structure of a Dimeric Oxidized form of Human Peroxiredoxin 5, J. Mol. Biol., 337, 2004, 1079-1090.
  • HANIQUE S, COLOMBO M, GOORMAGHTIGH E, SOUMILLION P, FRÈRE J, JORIS B, Evidence of an intra molecular interaction between the two domains of the BlaR1 penicillin receptor during the signal transduction, J. Biol. Chem., 279, 2004, 14264-14272.
  • MATHONET P, FASTREZ J, Engineering of non-natural receptors. Current Opinion in Structural Biology, 14(4), 505-511

2003

  • FERNANDEZ-GACIO A, UGUEN M, FASTREZ J, Phage display as a tool for the directed evolution of enzymes. Trends in Biotechnology, 21(9), 408-414.

2002

  • LEGENDRE D, FASTREZ J, SOUMILLION P, Genetically engineered enzymes as new tools for diagnostics, Bioforum International, 6, 2002, 185-187.
  • SOUMILLION P, FASTREZ J, Investigation of phage display for the directed evolution of enzymes, In: Directed molecular evolution of proteins, Brakmann S. and Johnsson K. ed., Wiley-VCH, 2002, 79-110.
  • LEGENDRE D, VUCIC B, HOUGARDY V, GIRBOUX A-L, HENRIOUL C, VAN HAUTE J, SOUMILLION P, FASTREZ J, TEM-1 beta-lactamase as a scaffold for protein recognition and assay, Protein Sci., 11, 2002, 1506-1518.
  • LEGENDRE D, FASTREZ J,  Construction and exploitation in model experiments of functional selection of a landscape library expressed from a phagemid. Gene, 290(1-2), 203-215.

2001

  • LEGENDRE D, SOUMILLION P, FASTREZ J, Method for the selective survival or selective growth of a target cell by the use of a conjugate, its use in therapeutics and/or diagnostics and the preparation of said conjugate (brevet), PCT Int. Appl., WO 01/97854, 2001.
  • SOUMILLION P, FASTREZ J, Novel concepts for selection of catalytic activity, Curr. Opin. Biotech., 12, 2001, 387-394.
  • PONSARD I, GALLENI M, SOUMILLION P, FASTREZ J, Selection of metalloenzymes by catalytic activity using phage display and catalytic elution, ChemBioChem., 2, 2001, 253-259.
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| 11/05/2012 |