Organic chemistry [ LMAPR1230 ]

> https://moodleucl.uclouvain.be/course/view.php?id=8644

FSAB 1301 (Chemistry 1) or a similar course

FSAB 1302 (Chemistry 2) or a similar course

The course is divided in three parts. The first part deals with 'generalities' required for a good understanding of the reactivity in organic chemistry, namely the reasons why organic compounds do or do not react in given conditions.

The second part describes the chemical behavior of the main organic compounds, illustrating the relationships between the structure of a given functional group and its reactivity. The lessons will be frequently illustrated with examples from other disciplines such as materials science and life sciences.

The third part consists in an introduction to the main separation techniques used in the chemical industry and to the oil refining industry in particular. It addresses the thermodynamics of phase equilibria (liquid-liquid and liquid-vapor) and describes some practical applications of these equilibria, such as liquid-liquid extraction or fractional distillation. 

Contribution of the course to the program objectives

Regarding the learning outcomes of the program of Bachelor in Engineering Sciences, this course contributes to the development and the acquisition of the following learning outcomes:

LO 1.1 : Apply concepts, laws, reasoning to disciplinary reduced problems.

Specific learning outcomes of the course

At the end of the course, the student will be able to:

• distinguish the different types of isomers (structure and geometrical isomers and stereoisomers) ;
• recognize the different types of reactants (nucleophiles, electrophiles, radicals, acids and bases) ;
• describe the electrons migration within an organic molecule (inductive and conjugation effects) as well as during a chemical reaction between two given compounds;
• recognize and represent the main functional groups of organic compounds ;
• establish relations between molecular and spatial structures of organic molecules and some properties, in particular, their reactivity ;
• predict and explain the expected result for the main types of organic reactions, including their mechanism;
• explain the utility of the fugacity and activity concepts;
• explain how the chemical process industry takes advantage of the various equation of state- or activity coefficients-based models to compute thermodynamic properties of liquid-vapor or liquid-liquid mixtures at equilibrium;
• explain the operation principles of a distillation columns for binary mixtures, of a crude oil distillation column or of a liquid-liquid extraction;
• explain the main units composing an oil refinery. 

The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.

Students are evaluated through a final written examination

The course is based on lectures and exercises-based learning

Part 1

1. Structure, chemical bonds and geometry of organic molecules

2. Isomerism

3. Reactivity in organic chemistry (energy diagrams, intermediates, types of reactants, electronic effects)

Part 2

4. Alkanes , alkenes and alkynes

5. Alkyl halides

6. Aromatic compounds

7. Alcohols, thiols, ethers and epoxydes

8. Aldehydes and ketones

9. Carboxylic acids and their derivatives

10. Amines and their derivatives

Part 3

11. Phase equilibria : real systems with one or several constituents

12. Practical applications of phase equilibria

13. Introduction to the refining industry

The slides presented during the lectures and the exercices are available on Moodle.

Recommended reference books :

• L. Craine, D. Hart, C. Hadad, Chimie Organique 1 et 2, Dunod, 2008
• D. Klein, Organic Chemistry, Wiley, 2011