Publications

Abdul Khaliq, Hafiz ; Al Houayek, Mireille ; Quetin-Leclercq, Joëlle ; Muccioli, Giulio. 5'AMP-activated protein kinase: an emerging target of phytochemicals to treat chronic inflammatory diseases.. In: Critical reviews in food science and nutrition, , p. [1-26] (2022). doi:10.1080/10408398.2022.2145264 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/270953

Ranaivo, Harimalala ; Zhang, Zhengxiao ; Alligier, Maud ; Van Den Berghe, Laurie ; Sothier, Monique ; Lambert-Porcheron, Stéphanie ; Feugier, Nathalie ; Cuerq, Charlotte ; Machon, Christelle ; Neyrinck, Audrey M. ; Seethaler, Benjamin ; Rodriguez, Julie ; Roumain, Martin ; Muccioli, Giulio ; Maquet, Véronique ; Laville, Martine ; Bischoff, Stephan C ; Walter, Jens ; Delzenne, Nathalie M. ; Nazare, Julie-Anne. Chitin-glucan supplementation improved postprandial metabolism and altered gut microbiota in subjects at cardiometabolic risk in a randomized trial.. In: Scientific reports, Vol. 12, no.1, p. 8830 [1-14] (2022). doi:10.1038/s41598-022-12920-z.

http://hdl.handle.net/2078.1/262730

Mozaheb, Negar ; Van Der Smissen, Patrick ; Opsomer, Tomas ; Mignolet, Eric ; Terrasi, Romano ; Paquot, Adrien ; Larondelle, Yvan ; Dehaen, Wim ; Muccioli, Giulio ; Mingeot-Leclercq, Marie-Paule. Contribution of Membrane Vesicle to Reprogramming of Bacterial Membrane Fluidity in Pseudomonas aeruginosa.. In: mSphere, Vol. 7, no. 3, p. e0018722 [1-13] (2022). doi:10.1128/msphere.00187-22.

http://hdl.handle.net/2078.1/262731

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle. Dereplication and Quantification of Major Compounds of L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages.. In: Molecules (Basel, Switzerland), Vol. 27, no.3, p. 963 [1-19] (2022). doi:10.3390/molecules27030963.

http://hdl.handle.net/2078.1/258760

Bozzato, Elia ; Tsakiris, Nikolaos ; Paquot, Adrien ; Muccioli, Giulio ; Bastiancich, Chiara ; Préat, Véronique. Dual-drug loaded nanomedicine hydrogel as a therapeutic platform to target both residual glioblastoma and glioma stem cells.. In: International journal of pharmaceutics, Vol. 628, p. 122341 [1-12] (2022). doi:10.1016/j.ijpharm.2022.122341.

http://hdl.handle.net/2078.1/276322

Le Roy, Tiphaine ; Moens De Hase, Emilie ; Van Hul, Matthias ; Paquot, Adrien ; Pelicaen, Rudy ; Régnier, Marion ; Depommier, Clara ; Druart, Céline ; Everard, Amandine ; Maiter, Dominique ; Delzenne, Nathalie M. ; Bindels, Laure B. ; de Barsy, Marie ; Loumaye, Audrey ; Hermans, Michel ; Thissen, Jean-Paul ; Vieira-Silva, Sara ; Falony, Gwen ; Raes, Jeroen ; Muccioli, Giulio ; Cani, Patrice D.. Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice. In: Gut, Vol. 71, p. 534–543 (2022). doi:10.1136/gutjnl-2020-323778.

http://hdl.handle.net/2078.1/248284

Copperi, Francesca ; Schleis, Inna ; Roumain, Martin ; Muccioli, Giulio ; Casola, Stefano ; Klingenspor, Martin ; Pfeifer, Alexander ; Gnad, Thorsten. EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes.. In: Communications biology, Vol. 5, no.1, p. 280 [1-9] (2022). doi:10.1038/s42003-022-03201-6.

http://hdl.handle.net/2078.1/262732

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Neyts, Tanguy ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle. Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents. In: Toxicology Reports, Vol. 9, p. 1742-1753 (2022). doi:10.1016/j.toxrep.2022.09.004.

http://hdl.handle.net/2078.1/265887

Barington, Line ; Christensen, Liv von Voss ; Pedersen, Kristian Kåber ; Niss Arfelt, Kristine ; Roumain, Martin ; Jensen, Kristian Høj Reveles ; Kjær, Viktoria Madeline Skovgaard ; Daugvilaite, Viktorija ; Kearney, John F ; Christensen, Jan Pravsgaard ; Hjortø, Gertrud Malene ; Muccioli, Giulio ; Holst, Peter Johannes ; Rosenkilde, Mette Marie. GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity.. In: Cells, Vol. 11, no.3, p. 494 [1-18] (2022). doi:10.3390/cells11030494.

http://hdl.handle.net/2078.1/262733

Berland, Chloé ; Castel, Julien ; Terrasi, Romano ; Montalban, Enrica ; Foppen, Ewout ; Martin, Claire ; Muccioli, Giulio ; Luquet, Serge ; Gangarossa, Giuseppe. Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis.. In: Molecular psychiatry, Vol. 27, no.4, p. 2340-2354 (2022). doi:10.1038/s41380-021-01428-z.

http://hdl.handle.net/2078.1/276271

Labrak, Yasmine ; Heurtault, Béatrice ; Frisch, Benoît ; Saulnier, Patrick ; Lepeltier, Elise ; Miron, Veronique E ; Muccioli, Giulio ; des Rieux, Anne. Impact of anti-PDGFRα antibody surface functionalization on LNC uptake by oligodendrocyte progenitor cells.. In: International journal of pharmaceutics, Vol. 618, p. 121623 (2022). doi:10.1016/j.ijpharm.2022.121623.

http://hdl.handle.net/2078.1/261156

De Berdt, Pauline ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Bouzin, Caroline ; Paquot, Adrien ; Gratpain, Viridiane ; Loriot, Axelle ; Payen, Valery ; Bearzatto, Bertrand ; Muccioli, Giulio ; Gatto, Laurent ; Diogenes, A ; des Rieux, Anne. The human dental apical papilla promotes spinal cord repair through a paracrine mechanism.. In: Cellular and molecular life sciences : CMLS, Vol. 79, no.5, p. 252 (2022). doi:10.1007/s00018-022-04210-8.

http://hdl.handle.net/2078.1/261157

Yelek, Caner ; Mignion, Lionel ; Paquot, Adrien ; Bouzin, Caroline ; Corbet, Cyril ; Muccioli, Giulio ; Cani, Patrice D. ; Jordan, Bénédicte. Tumor Metabolism Is Affected by Obesity in Preclinical Models of Triple-Negative Breast Cancer. In: Cancers, Vol. 14, no. 3, p. 562 [1-16] (2022). doi:10.3390/cancers14030562.

http://hdl.handle.net/2078.1/257713

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio. 25-Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice.. In: FASEB journal, Vol. 35, no.4, p. e21514 [1-19] (2021). doi:10.1096/fj.202002555R.

http://hdl.handle.net/2078.1/245667

Stillemans, Gabriel ; Paquot, Adrien ; Muccioli, Giulio ; Hoste, Emilia ; Panin, Nadtha ; Åsberg, Anders ; Balligand, Jean-Luc ; Haufroid, Vincent ; Elens, Laure. Atorvastatin population pharmacokinetics in a real‐life setting: Influence of genetic polymorphisms and association with clinical response. In: Clinical and Translational Science, (2021). doi:10.1111/cts.13185.

http://hdl.handle.net/2078.1/253932

Thibaut, Morgane ; Gillard, Justine ; Dolly, Adeline ; Roumain, Martin ; Leclercq, Isabelle ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Bindels, Laure B.. Bile Acid Dysregulation Is Intrinsically Related to Cachexia in Tumor-Bearing Mice. In: Cancers, Vol. 13, no.24, p. 6389 [1-17] (2021). doi:10.3390/cancers13246389.

http://hdl.handle.net/2078.1/255259

Al Houayek, Mireille ; Ameraoui, Hafsa ; Muccioli, Giulio. Bioactive lipids in inflammatory bowel diseases - From pathophysiological alterations to therapeutic opportunities.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1866, no.2, p. 158854 [1-18] (2021). doi:10.1016/j.bbalip.2020.158854.

http://hdl.handle.net/2078.1/238828

Ange, Marine ; De Poortere, Julien ; Ginion, Audrey ; Battault, Sylvain ; Dechamps, Mélanie ; Muccioli, Giulio ; Roumain, Martin ; Morelle, Johann ; Druart, Sébastien ; Mathivet, Thomas ; Bertrand, Luc ; Castanares Zapatero, Diego ; Horman, Sandrine ; Beauloye, Christophe. Canagliflozin protects against sepsis capillary leak syndrome by activating endothelial α1AMPK.. In: Scientific reports, Vol. 11, no. 1, p. 13700 [1-13] (2021). doi:10.1038/s41598-021-93156-1.

http://hdl.handle.net/2078.1/249133

Van Den Brûle, Sybille ; Rappe, Margaux ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Paquot, Adrien ; Muccioli, Giulio ; Lison, Dominique. Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice.. In: Particle and fibre toxicology, Vol. 18, no. 1, p. 7 [1-15] (2021). doi:10.1186/s12989-021-00400-7.

http://hdl.handle.net/2078.1/244331

Perez, Laeticia ; Scarcello, Eleonora ; Ibouraadaten, Saloua ; Yakoub, Yousof ; Leinardi, Riccardo ; Ambroise, Jérôme ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Paquot, Adrien ; Muccioli, Giulio ; Bouzin, Caroline ; Van Den Brûle, Sybille ; Lison, Dominique. Dietary nanoparticles alter the composition and function of the gut microbiota in mice at dose levels relevant for human exposure.. In: Food and chemical toxicology, Vol. 154, p. 112352 [1-13] (2021). doi:10.1016/j.fct.2021.112352.

http://hdl.handle.net/2078.1/252340

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Ben Kouidar, Youssef ; Paquot, Adrien ; Muccioli, Giulio ; Al Houayek, Mireille. Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.. In: The FASEB Journal, Vol. 35, no. 4, p. e21411 [1-16] (2021). doi:10.1096/fj.202002468R.

http://hdl.handle.net/2078.1/241768

Gratpain, Viridiane ; Mwema, Ariane ; Labrak, Yasmine ; Muccioli, Giulio ; Van Pesch, Vincent ; des Rieux, Anne. Extracellular vesicles for the treatment of central nervous system diseasesExtracellular vesicles for the treatment of central nervous system diseases. In: Advanced drug delivery reviews, Vol. 174, p. 535-552 (2021). doi:10.1016/j.addr.2021.05.006.

http://hdl.handle.net/2078.1/246588

Genton, Laurence ; Pruijm, Menno ; Teta, Daniel ; Bassi, Isabelle ; Cani, Patrice D. ; Gaïa, Nadia ; Herrmann, François R ; Marangon, Nicola ; Mareschal, Julie ; Muccioli, Giulio ; Stoermann, Catherine ; Suriano, Francesco ; Wurzner-Ghajarzadeh, Arlene ; Lazarevic, Vladimir ; Schrenzel, Jacques. Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients.. In: Journal of cachexia, sarcopenia and muscle, , p. [1-13] (2021). doi:10.1002/jcsm.12781 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/252326

Abot, Anne ; Wemelle, Eve ; Laurens, Claire ; Paquot, Adrien ; Pomie, Nicolas ; Carper, Deborah ; Bessac, Arnaud ; Mas Orea, Xavier ; Fremez, Christophe ; Fontanie, Maxime ; Lucas, Alexandre ; Lesage, Jean ; Everard, Amandine ; Meunier, Etienne ; Dietrich, Gilles ; Muccioli, Giulio ; Moro, Cedric ; Cani, Patrice D. ; Knauf, Claude. Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice.. In: Gut, Vol. 70, no. 6, p. 1078-1087 (2021). doi:10.1136/gutjnl-2019-320230.

http://hdl.handle.net/2078.1/238807

Cloos, Anne-Sophie ; Daenen, Laura G. M. ; Maja, Mauriane ; Stommen, Amaury ; Vanderroost, Juliette ; Van Der Smissen, Patrick ; Rab, Minke ; Westerink, Jan ; Mignolet, Eric ; Larondelle, Yvan ; Terrasi, Romano ; Muccioli, Giulio ; Dumitru, Andra-Cristina ; Alsteens, David ; van Wijk, Richard ; Tyteca, Donatienne. Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study. In: Frontiers in Physiology, Vol. 12, no. 2, p. 638027 [1-22] (2021). doi:10.3389/fphys.2021.638027.

http://hdl.handle.net/2078.1/245325

Thibaut, Morgane ; Sboarina, Martina ; Roumain, Martin ; Pötgens, Sarah ; Neyrinck, Audrey M. ; Destrée, Florence ; Gillard, Justine ; Leclercq, Isabelle ; Dachy, Guillaume ; Demoulin, Jean-Baptiste ; Tailleux, Anne ; Lestavel, Sophie ; Rastelli, Marialetizia ; Everard, Amandine ; Cani, Patrice D. ; Porporato, Paolo E ; Loumaye, Audrey ; Thissen, Jean-Paul ; Muccioli, Giulio ; Delzenne, Nathalie M. ; Bindels, Laure B.. Inflammation-induced cholestasis in cancer cachexia.. In: Journal of cachexia, sarcopenia and muscle, Vol. 12, no. 1, p. 70-20 (2021). doi:10.1002/jcsm.12652.

http://hdl.handle.net/2078.1/241139

Bottemanne, Pauline ; Guillemot-Legris, Owein ; Paquot, Adrien ; Masquelier, Julien ; Malamas, Michael ; Makriyannis, Alexandros ; Al Houayek, Mireille ; Muccioli, Giulio. N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.. In: Neurotherapeutics, , p. [1-19] (2021). doi:10.1007/s13311-021-01074-x (Accepté/Sous presse).

http://hdl.handle.net/2078.1/252337

Suriano, Francesco ; Vieira-Silva, Sara ; Falony, Gwen ; Roumain, Martin ; Paquot, Adrien ; Pelicaen, Rudy ; Régnier, Marion ; Delzenne, Nathalie M. ; Raes, Jeroen ; Muccioli, Giulio ; Van Hul, Matthias ; Cani, Patrice D.. Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin. In: Microbiome, Vol. 9, no.1, p. 147 (2021). doi:10.1186/s40168-021-01097-8.

http://hdl.handle.net/2078.1/249367

Neyrinck, Audrey M. ; Rodriguez, Julie (co-first author) ; Zhang, Zhengxiao ; Seethaler, Benjamin ; Robles Sanchez, Candido ; Roumain, Martin ; Hiel, Sophie ; Bindels, Laure B. ; Cani, Patrice D. ; Paquot, Nicolas ; Cnop, Miriam ; Nazare, Julie-Anne ; Laville, Martine ; Muccioli, Giulio ; Bischoff, Stephan C ; Walter, Jens ; Thissen, Jean-Paul ; Delzenne, Nathalie M.. Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial.. In: European journal of nutrition, Vol. 60, no. 6, p. 3159-3170 (2021). doi:10.1007/s00394-021-02484-5 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/243405

Buya, Aristote ; Terrasi, Romano ; Mbinze, Jérémie K ; Muccioli, Giulio ; Beloqui Garcia, Ana ; Memvanga, Patrick B ; Préat, Véronique. Quality-by-Design-Based Development of a Voxelotor Self-Nanoemulsifying Drug-Delivery System with Improved Biopharmaceutical Attributes.. In: Pharmaceutics, Vol. 13, no.9, p. 1388 [1-20] (2021). doi:10.3390/pharmaceutics13091388.

http://hdl.handle.net/2078.1/252334

Lison, Dominique ; Ambroise, Jérôme ; Leinardi, Riccardo ; Ibouraadaten, Saloua ; Yakoub, Yousof ; Deumer, Gladys ; Haufroid, Vincent ; Paquot, Adrien ; Muccioli, Giulio ; Van Den Brûle, Sybille. Systemic effects and impact on the gut microbiota upon subacute oral exposure to silver acetate in rats.. In: Archives of toxicology, Vol. 95, no. 4, p. 1251-1266 (2021). doi:10.1007/s00204-021-02998-1.

http://hdl.handle.net/2078.1/244989

Guillemot-Legris, Owein ; Muccioli, Giulio. The oxysterome and its receptors as pharmacological targets in inflammatory diseases.. In: British journal of pharmacology, (2021). doi:10.1111/bph.15479 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/245643

Pollet, Hélène ; Cloos, Anne-Sophie (co-first author) ; Stommen, Amaury ; Vanderroost, Juliette ; Conrard, Louise ; Paquot, Adrien ; Ghodsi, Marine ; Carquin, Mélanie ; Léonard, Anne-Catherine ; Guthmann, Manuel ; Lingurski, Maxime ; Vermylen, Christiane ; Killian, Theodore ; Gatto, Laurent ; Rider, Mark H. ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Vikkula, Miikka ; Brouillard, Pascal ; Van Der Smissen, Patrick ; Muccioli, Giulio ; Tyteca, Donatienne. Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis. In: Biomolecules, Vol. 10, no. 8, p. 1120 [1-25] (2020). doi:10.3390/biom10081120.

http://hdl.handle.net/2078.1/232537

Yelek, Caner ; Mignion, Lionel ; Joudiou, Nicolas ; Terrasi, Romano ; Gourgue, Florian ; Van Hul, Matthias ; Delzenne, Nathalie M. ; Gallez, Bernard ; Corbet, Cyril ; Muccioli, Giulio ; Feron, Olivier ; Cani, Patrice D. ; Jordan, Bénédicte. Acetate: Friend or foe against breast tumour growth in the context of obesity?. In: Journal of Cellular and Molecular Medicine, Vol. 24, no. 24, p. 14195-14204 (2020). doi:10.1111/jcmm.16034.

http://hdl.handle.net/2078.1/236998

Phung, Austin S. ; Bannenberg, Gerard ; Vigor, Claire ; Reversat, Guillaume ; Oger, Camille ; Roumain, Martin ; Galano, Jean-Marie ; Durand, Thierry ; Muccioli, Giulio ; Ismail, Adam ; Wang, Selina C.. Chemical Compositional Changes in Over-Oxidized Fish Oils. In: Foods, Vol. 9, no.10, p. 1501 (2020). doi:10.3390/foods9101501.

http://hdl.handle.net/2078.1/237577

Tsakiris, Nikolaos ; Fauvet, Frédérique ; Ruby, Samia ; Puisieux, Alain ; Paquot, Adrien ; Muccioli, Giulio ; Vigneron, Arnaud M ; Préat, Véronique. Combined nanomedicines targeting colorectal cancer stem cells and cancer cells.. In: Journal of controlled release, Vol. 326, p. 387-395 (2020). doi:10.1016/j.jconrel.2020.07.025.

http://hdl.handle.net/2078.1/238835

Le Roy, Tiphaine ; Van Der Smissen, Patrick ; Paquot, Adrien ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Collet, Jean-François ; Cani, Patrice D.. Dysosmobacter welbionis gen. nov., sp. nov., isolated from human faeces and emended description of the genus Oscillibacter.. In: International journal of systematic and evolutionary microbiology, Vol. 70, no. 9, p. 4851-4858 (2020). doi:10.1099/ijsem.0.003547.

http://hdl.handle.net/2078.1/226713

Al Houayek, Mireille ; Bannenberg, Gerard ; Muccioli, Giulio ; Norel, Xavier ; Yao, Chengcan ; Schebb, Nils Helge. Editorial-Special issue of the 7 European workshop on lipid mediators.. In: Prostaglandins & other lipid mediators, Vol. 148, p. 106421 [1-3] (2020). doi:10.1016/j.prostaglandins.2020.106421.

http://hdl.handle.net/2078.1/241764

Van Hul, Matthias ; Le Roy, Tiphaine ; Prifti, Edi ; Dao, Maria Carlota ; Paquot, Adrien ; Zucker, Jean-Daniel ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Clément, Karine ; Cani, Patrice D.. From correlation to causality: the case of Subdoligranulum. In: Gut Microbes, Vol. 12, no.1, p. 1-13 (2020). doi:10.1080/19490976.2020.1849998.

http://hdl.handle.net/2078.1/239728

Manca, Claudia ; Boubertakh, Besma ; Leblanc, Nadine ; Deschênes, Thomas ; Lacroix, Sebastien ; Martin, Cyril ; Houde, Alain ; Veilleux, Alain ; Flamand, Nicolas ; Muccioli, Giulio ; Raymond, Frédéric ; Cani, Patrice D. ; Di Marzo, Vincenzo ; Silvestri, Cristoforo. Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling.. In: Journal of lipid research, Vol. 61, no.1, p. 70-85 (2020). doi:10.1194/jlr.RA119000424.

http://hdl.handle.net/2078.1/225749

Briand-Mésange, Fabienne ; Pons, Véronique ; Allart, Sophie ; Masquelier, Julien ; Chicanne, Gaëtan ; Beton, Nicolas ; Payrastre, Bernard ; Muccioli, Giulio ; Ausseil, Jérôme ; Davignon, Jean-Luc ; Salles, Jean-Pierre ; Chap, Hugues. Glycerophosphodiesterase 3 (GDE3) is a lysophosphatidylinositol-specific ectophospholipase C acting as an endocannabinoid signaling switch.. In: The Journal of biological chemistry, Vol. 295, no.46, p. 15767-15781 (2020). doi:10.1074/jbc.RA120.015278.

http://hdl.handle.net/2078.1/245676

Lefort, Charlotte ; Roumain, Martin ; Van Hul, Matthias ; Rastelli, Marialetizia ; Manco, Rita ; Leclercq, Isabelle ; Delzenne, Nathalie M. ; Di Marzo, Vincenzo ; Flamand, Nicolas ; Luquet, Serge ; Silvestri, Cristoforo ; Muccioli, Giulio ; Cani, Patrice D.. Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism. In: Cells, Vol. 9, no. 5, p. 1247 [1-23] (2020). doi:10.3390/cells9051247.

http://hdl.handle.net/2078.1/229912

Demaret, Tanguy ; Evraerts, Jonathan ; Ravau, Joachim ; Roumain, Martin ; Muccioli, Giulio ; Najimi, Mustapha ; Sokal, Etienne. High Dose Versus Low Dose Syngeneic Hepatocyte Transplantation in -G844D NMRI Mouse Model is Safe but Does Not Achieve Long Term Engraftment. In: Cells, Vol. 10, no.1, p. 40 [1-12] (2020). doi:10.3390/cells10010040.

http://hdl.handle.net/2078.1/245673

Demaret, Tanguy ; Evraerts, Jonathan ; Ravau, Joachim ; Roumain, Martin ; Muccioli, Giulio ; Najimi, Mustapha ; Sokal, Etienne. High Dose Versus Low Dose Syngeneic Hepatocyte Transplantation in -G844D NMRI Mouse Model is Safe but Does Not Achieve Long Term Engraftment.. In: Cells, Vol. 10, no. 1, p. 40 [1-12] (2020). doi:10.3390/cells10010040.

http://hdl.handle.net/2078.1/261816

Valderrama, Jaime A. ; Ríos, David ; Muccioli, Giulio ; Buc Calderon, Pedro ; Benites, Julio. In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study. In: Molecules, Vol. 25, no.4, p. 953 (2020). doi:10.3390/molecules25040953 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/231136

Cloos, Anne-Sophie ; Ghodsi, Marine ; Stommen, Amaury ; Vanderroost, Juliette ; Dauguet, Nicolas ; Pollet, Hélène ; D'Auria, Ludovic ; Mignolet, Eric ; Larondelle, Yvan ; Terrasi, Romano ; Muccioli, Giulio ; Van Der Smissen, Patrick ; Tyteca, Donatienne. Interplay Between Plasma Membrane Lipid Alteration, Oxidative Stress and Calcium-Based Mechanism for Extracellular Vesicle Biogenesis From Erythrocytes During Blood Storage.. In: Frontiers in Physiology, Vol. 11, p. 712 [1-23] (2020). doi:10.3389/fphys.2020.00712.

http://hdl.handle.net/2078.1/241697

Rastelli, Marialetizia ; Van Hul, Matthias ; Terrasi, Romano ; Lefort, Charlotte ; Régnier, Marion ; Beiroa, Daniel ; Delzenne, Nathalie M. ; Everard, Amandine ; Nogueiras, Rubén ; Luquet, Serge ; Muccioli, Giulio ; Cani, Patrice D.. Intestinal NAPE-PLD contributes to short-term regulation of food intake via gut-to-brain axis.. In: American journal of physiology. Endocrinology and metabolism, Vol. 319, no.3, p. E647-E657 (2020). doi:10.1152/ajpendo.00146.2020.

http://hdl.handle.net/2078.1/236182

Demaret, Tanguy ; Roumain, Martin ; Ambroise, Jérôme ; Evraerts, Jonathan ; Ravau, Joachim ; Bouzin, Caroline ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Stepman, Hedwig ; Marie, Sandrine ; Vincent, Marie-Françoise ; Muccioli, Giulio ; Najimi, Mustapha ; Sokal, Etienne. Longitudinal study of Pex1-G844D NMRI mouse model: A robust pre-clinical model for mild Zellweger spectrum disorder. In: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Vol. 1866, no. 11, p. 165900 [1-18] (2020). doi:10.1016/j.bbadis.2020.165900.

http://hdl.handle.net/2078.1/235105

Rodriguez, Julie ; Neyrinck, Audrey M. ; Zhang, Zhengxiao ; Seethaler, Benjamin ; Nazare, Julie-Anne ; Robles Sanchez, Candido ; Roumain, Martin ; Muccioli, Giulio ; Bindels, Laure B. ; Cani, Patrice D. ; Maquet, Véronique ; Laville, Martine ; Bischoff, Stephan C ; Walter, Jens ; Delzenne, Nathalie M.. Metabolite profiling reveals the interaction of chitin-glucan with the gut microbiota.. In: Gut microbes, Vol. 12, no. 1, p. 1810530 [1-15] (2020). doi:10.1080/19490976.2020.1810530.

http://hdl.handle.net/2078.1/236181

Ríos, David ; Valderrama, Jaime A ; Cautin, Miriam ; Tapia, Milko ; Salas, Felipe ; Guerrero-Castilla, Angélica ; Muccioli, Giulio ; Buc Calderon, Pedro ; Benites, Julio. New 2-Acetyl-3-aminophenyl-1,4-naphthoquinones: Synthesis and Antiproliferative Activities on Breast and Prostate Human Cancer Cells.. In: Oxidative medicine and cellular longevity, Vol. 2020, p. 8939716 [1-11] (2020). doi:10.1155/2020/8939716.

http://hdl.handle.net/2078.1/238831

Diermeier, Theresa ; Meredith, Sean J ; Irrgang, James J ; Zaffagnini, Stefano ; Kuroda, Ryosuke ; Hochino, Yuichi ; Samuelsson, Kristian ; Smith, Clair Nicole ; Popchak, Adam ; Musahl, Volker ; Sheean, Andrew ; Burnham, Jeremy M ; Lian, Jayson ; Smith, Clair ; Popchak, Adam ; Herbst, Elmar ; Pfeiffer, Thomas ; Araujo, Paulo ; Oostdyk, Alicia ; Guenther, Daniel ; Ohashi, Bruno ; Irrgang, James J ; Fu, Freddie H ; Nagamune, Kouki ; Kurosaka, Masahiro ; Kuroda, Ryosuke ; Hochino, Yuichi ; Grassi, Alberto ; Muccioli, Giulio ; Lopomo, Nicola ; Signorelli, Cecilia ; Raggi, Federico ; Zaffagnini, Stefano ; Horvath, Alexandra ; Svantesson, Eleonor ; Senorski, Eric Hamrin ; Sundemo, David ; Bjoernsson, Haukur ; Ahlden, Mattias ; Desai, Neel ; Samuelsson, Kristian ; Karlsson, Jon. Patient-Reported and Quantitative Outcomes of Anatomic Anterior Cruciate Ligament Reconstruction With Hamstring Tendon Autografts., collab. PIVOT Study Group. In: Orthopaedic journal of sports medicine, Vol. 8, no.7, p. [1-7] (2020). doi:10.1177/2325967120926159 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/238837

Orefice, Nicola S ; Guillemot-Legris, Owein ; Capasso, Rosanna ; Bottemanne, Pauline ; Hantraye, Philippe ; Caraglia, Michele ; Orefice, Giuseppe ; Al Houayek, Mireille ; Muccioli, Giulio. miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions.. In: eLife, Vol. 9, p. e56916 [1-25] (2020). doi:10.7554/eLife.56916.

http://hdl.handle.net/2078.1/238833

Morelle, Axel ; Caruano, Joséphine ; Feledziak, Marion ; Michaux, Catherine ; Perpète, Eric ; Muccioli, Giulio ; Marchand-Brynaert, Jacqueline ; Robiette, Raphaël. β-lactams to act on the endocannabinoid system. In: Chimie Nouvelle, Vol. 134, p. 41 (2020).

http://hdl.handle.net/2078.1/241820

Le Roy, Tiphaine ; Van Der Smissen, Patrick ; Paquot, Adrien ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Collet, Jean-François ; Cani, Patrice D.. Butyricimonas faecalis sp. nov., isolated from human faeces and emended description of the genus Butyricimonas.. In: International journal of systematic and evolutionary microbiology, Vol. 69, no.3, p. 833-838 (2019). doi:10.1099/ijsem.0.003249.

http://hdl.handle.net/2078.1/214483

Ippolito, Luigi ; Morandi, Andrea ; Taddei, Maria Letizia ; Parri, Matteo ; Comito, Giuseppina ; Iscaro, Alessandra ; Raspollini, Maria Rosaria ; Magherini, Francesca ; Rapizzi, Elena ; Masquelier, Julien ; Muccioli, Giulio ; Sonveaux, Pierre ; Chiarugi, Paola ; Giannoni, Elisa. Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer.. In: Oncogene, Vol. 38, no. 27, p. 5339-5355 (2019). doi:10.1038/s41388-019-0805-7 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/215417

Guillemot-Legris, Owein ; Mutemberezi, Valentin ; Buisseret, Baptiste ; Paquot, Adrien ; Palmieri, Vittoria ; Bottemanne, Pauline ; Lemaire, Julien ; Rahier, Jean-François ; Al Houayek, Mireille ; Muccioli, Giulio. Colitis alters oxysterol metabolism and is affected by 4β-hydroxycholesterol administration.. In: Journal of Crohn's & colitis, Vol. 13, no. 2, p. 218-229 (2019). doi:10.1093/ecco-jcc/jjy157.

http://hdl.handle.net/2078.1/204079

Buisseret, Baptiste ; Al Houayek, Mireille ; Guillemot-Legris, Owein ; Muccioli, Giulio. Endocannabinoid and Prostanoid Crosstalk in Pain. In: Trends in Molecular Medicine, Vol. 25, p. 882-896 (2019). doi:10.1016/j.molmed.2019.04.009.

http://hdl.handle.net/2078.1/217090

Benites, Julio ; Valderrama, Jaime A ; Ramos, Maryan ; Valenzuela, Maudy ; Guerrero-Castilla, Angélica ; Muccioli, Giulio ; Buc Calderon, Pedro. Half-Wave Potentials and In Vitro Cytotoxic Evaluation of 3-Acylated 2,5-(phenylamino)-1,4-benzoquinones on Cancer Cells.. In: Molecules (Basel, Switzerland), Vol. 24, no.9, p. 1780 [1-14] (2019). doi:10.3390/molecules24091780.

http://hdl.handle.net/2078.1/216900

Everard, Amandine ; Plovier, Hubert ; Rastelli, Marialetizia ; Van Hul, Matthias ; de Wouters d’Oplinter, Alice ; Geurts, Lucie ; Druart, Céline ; Robine, Sylvie ; Delzenne, Nathalie M. ; Muccioli, Giulio ; de Vos, Willem M. ; Luquet, Serge ; Flamand, Nicolas ; Di Marzo, Vincenzo ; Cani, Patrice D.. Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis. In: Nature Communications, Vol. 10, p. 457 [1-17] (2019). doi:10.1038/s41467-018-08051-7.

http://hdl.handle.net/2078.1/212416

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Muccioli, Giulio ; Al Houayek, Mireille. Prostaglandin D2-glycerol ester decreases carrageenan-induced inflammation and hyperalgesia in mice. In: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, Vol. 1864, p. 609-619 (2019).

http://hdl.handle.net/2078.1/211917

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Al Houayek, Mireille ; Muccioli, Giulio. The α/β–hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids. In: The FASEB Journal, Vol. 33, no. 6, p. 7635-7646 (2019). doi:10.1096/fj.201802259r.

http://hdl.handle.net/2078.1/217091

Muccioli, Giulio ; Lizard, Gérard ; Iuliano, Luigi. Current trends in oxysterols & related sterols.. In: Biochimie : an international journal of biochemistry and molecular biology, Vol. 153, p. 1-2 (2018). doi:10.1016/j.biochi.2018.08.008.

http://hdl.handle.net/2078.1/204355

Masquelier, Julien ; Al Houayek, Mireille ; Terrasi, Romano ; Bottemanne, Pauline ; Paquot, Adrien ; Muccioli, Giulio. Lysophosphatidylinositols in inflammation and macrophage activation: Altered levels and anti-inflammatory effects.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1863, no.12, p. 1458-1468 (2018). doi:10.1016/j.bbalip.2018.09.003.

http://hdl.handle.net/2078.1/204354

Al Houayek, Mireille ; Masquelier, Julien ; Muccioli, Giulio. Lysophosphatidylinositols, from Cell Membrane Constituents to GPR55 Ligands. In: Trends in Pharmacological Sciences, Vol. 39, no.6, p. 586-604 (2018). doi:10.1016/j.tips.2018.02.011.

http://hdl.handle.net/2078.1/199630

Verstraeten, Sandrine ; Albert, Marie ; Paquot, Adrien ; Muccioli, Giulio ; Tyteca, Donatienne ; Mingeot-Leclercq, Marie-Paule. Membrane cholesterol delays cellular apoptosis induced by ginsenoside RH2, a steroid saponin. In: Toxicology and Applied Pharmacology, Vol. 352, p. 59–67 (2018). doi:10.1016/j.taap.2018.05.014.

http://hdl.handle.net/2078.1/198283

Milosevic, Tamara ; Payen, Valéry ; Sonveaux, Pierre ; Muccioli, Giulio ; Tulkens, Paul M. ; Van Bambeke, Françoise. Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes.. In: Antimicrobial Agents and Chemotherapy, Vol. 62, no. 3, p. e01599-17 [1-17] (2018). doi:10.1128/AAC.01599-17.

http://hdl.handle.net/2078.1/199907

Bottemanne, Pauline ; Muccioli, Giulio ; Al Houayek, Mireille. N -acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities. In: Drug Discovery Today, Vol. 23, no. 8, p. 1520-1529 (2018). doi:10.1016/j.drudis.2018.03.007.

http://hdl.handle.net/2078.1/199632

Mutemberezi, Valentin ; Buisseret, Baptiste ; Masquelier, Julien ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio. Oxysterol levels and metabolism in the course of neuroinflammation: insights from in vitro and in vivo models. In: Journal of Neuroinflammation, Vol. 15, no.1, p. 1-10 (2018). doi:10.1186/s12974-018-1114-8.

http://hdl.handle.net/2078.1/199633

Guillemot-Legris, Owein ; Buisseret, Baptiste ; Mutemberezi, Valentin ; Hermans, Emmanuel ; Deumens, Ronald ; Al Houayek, Mireille ; Muccioli, Giulio. Post-operative pain in mice is prolonged by diet-induced obesity and rescued by dietary intervention.. In: Brain, Behavior, and Immunity, (2018). doi:10.1016/j.bbi.2018.07.022.

http://hdl.handle.net/2078.1/204362

Xu, Yining ; Carradori, Dario ; Al Houayek, Mireille ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique ; Beloqui Garcia, Ana. Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.. In: Molecular pharmaceutics, Vol. 15, no. 1, p. 108-115 (2018). doi:10.1021/acs.molpharmaceut.7b00742.

http://hdl.handle.net/2078.1/204371

De Berdt, Pauline ; Bottemanne, Pauline ; Bianco, John ; Al Houayek, Mireille ; Diogenes, Anibal ; Llyod, Amy ; Gerardo-Nava, Jose ; Brook, Gary A. ; Miron, Véronique ; Muccioli, Giulio ; des Rieux, Anne. Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion. In: Cellular and Molecular Life Sciences, Vol. 75, p. 2843-2856 (2018). doi:10.1007/s00018-018-2764-5.

http://hdl.handle.net/2078.1/199631

Benites, Julio ; Valderrama, Jaime A ; Ramos, Maryan ; Muccioli, Giulio ; Buc Calderon, Pedro. Targeting Akt as strategy to kill cancer cells using 3-substituted 5-anilinobenzo[c]isoxazolequinones: A preliminary study.. In: Biomedicine & Pharmacotherapy, Vol. 97, p. 778-783 (2017). doi:10.1016/j.biopha.2017.10.108.

http://hdl.handle.net/2078.1/189656

Al Houayek, Mireille ; Buisseret, Baptiste ; Paquot, Adrien ; Guillemot-Legris, Owein ; Muccioli, Giulio. The endogenous bioactive lipid prostaglandin D2-glycerol ester reduces murine colitis via DP1 and PPARγ receptors. In: The FASEB Journal, , p. fj.201701205R (2018). doi:10.1096/fj.201701205r (Accepté/Sous presse).

http://hdl.handle.net/2078.1/199628

Beaumont, Martin ; Neyrinck, Audrey M. ; Olivares Sevilla, Marta ; Rodriguez, Julie ; de Rocca Serra, Audrey ; Roumain, Martin ; Bindels, Laure B. ; Cani, Patrice D. ; Evenepoel, Pieter ; Muccioli, Giulio ; Demoulin, Jean-Baptiste ; Delzenne, Nathalie M.. The gut microbiota metabolite indole alleviates liver inflammation in mice.. In: The FASEB Journal, Vol. 32, no. 12, p. fj201800544 [1-13] (2018). doi:10.1096/fj.201800544.

http://hdl.handle.net/2078.1/199591

Carradori, Dario ; Dos Santos, Andreia ; Masquelier, Julien ; Paquot, Adrien ; Saulnier, Patrick ; Eyer, Joël ; Préat, Véronique ; Muccioli, Giulio ; Mingeot-Leclercq, Marie-Paule ; des Rieux, Anne. The origin of neural stem cells impacts their interactions with targeted-lipid nanocapsules: Potential role of plasma membrane lipid composition and fluidity. In: Journal of Controlled Release, Vol. 292, p. 248-255 (2018). doi:10.1016/j.jconrel.2018.11.005.

http://hdl.handle.net/2078.1/204783

Newson, Justine ; Motwani, Madhur P. ; Kendall, Alexandra C. ; Nicolaou, Anna ; Muccioli, Giulio ; Al Houayek, Mireille ; Bennett, Melanie ; Van De Merwe, Rachel ; James, Sarah ; De Maeyer, Roel P.H. ; Gilroy, Derek W.. Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E 2. In: Cell Reports, Vol. 20, no. 13, p. 3162-3175 (2017). doi:10.1016/j.celrep.2017.08.098.

http://hdl.handle.net/2078.1/193464

Al Houayek, Mireille ; Bottemanne, Pauline ; Makriyannis, Alexandros ; Muccioli, Giulio. N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation. In: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, Vol. 1862, no. 5, p. 474-484 (2017). doi:10.1016/j.bbalip.2017.01.001.

http://hdl.handle.net/2078.1/181908

Guillemot, Owein ; Muccioli, Giulio. Obesity-Induced Neuroinflammation: Beyond the Hypothalamus. In: Trends in Neurosciences, Vol. 40, no.4, p. 237-253 (2017). doi:10.1016/j.tins.2017.02.005.

http://hdl.handle.net/2078.1/186000

Buyck, Julien ; Luyckx, C. ; Muccioli, Giulio ; Krause, K.M. ; Nichols, W. W. ; Tulkens, Paul M. ; Van Bambeke, Françoise. Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa. In: Journal of Antimicrobial Chemotherapy, Vol. 72, no.5, p. 1400-1409 (2017). doi:10.1093/jac/dkw587.

http://hdl.handle.net/2078.1/186492

Van Hee, Vincent F ; Labar, Daniel ; Dehon, Gwenaël ; Grasso, Debora ; Gregoire, Vincent ; Muccioli, Giulio ; Frédérick, Raphaël ; Sonveaux, Pierre. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors. In: OncoTarget, Vol. 8, no. 15, p. 24415-24428 (2017). doi:10.18632/oncotarget.14705.

http://hdl.handle.net/2078.1/179754

Bindels, Laure B. ; Segura Munoz, Rafael R ; Gomes-Neto, João Carlos ; Mutemberezi, Valentin ; Martínez, Inés ; Salazar, Nuria ; Cody, Elizabeth A ; Quintero-Villegas, Maria I ; Kittana, Hatem ; de Los Reyes-Gavilán, Clara G ; Schmaltz, Robert J ; Muccioli, Giulio ; Walter, Jens ; Ramer-Tait, Amanda E. Resistant starch can improve insulin sensitivity independently of the gut microbiota. In: Microbiome, Vol. 5, no.1, p. 12 [1-16] (2017). doi:10.1186/s40168-017-0230-5.

http://hdl.handle.net/2078.1/182300

Valderrama, Jaime A. ; Cabrera, Mónica ; Benites, Julio ; Ríos, David ; Inostroza-Rivera, Ricardo ; Muccioli, Giulio ; Buc Calderon, Pedro. Synthetic approaches and in vitro cytotoxic evaluation of 2-acyl-3-(3,4,5-trimethoxyanilino)-1,4-naphthoquinones. In: R S C Advances : an international journal to further the chemical sciences, Vol. 7, no.40, p. 24813-24821 (2017). doi:10.1039/c7ra03238b.

http://hdl.handle.net/2078.1/185913

Beloqui Garcia, Ana ; Al Houayek, Mireille ; Carradori, Dario ; Vanvarenberg, Kevin ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique. A Mechanistic Study on Nanoparticle-Mediated Glucagon-Like Peptide-1 (GLP-1) Secretion from Enteroendocrine L Cells.. In: Molecular Pharmaceutics, Vol. 13, no.12, p. 4222-4230 (2016). doi:10.1021/acs.molpharmaceut.6b00871.

http://hdl.handle.net/2078.1/178983

Beloqui Garcia, Ana ; Memvanga Bondo, Patrick ; Coco, Régis ; Reimondez-Troitiño, Sonia ; Al Houayek, Mireille ; Muccioli, Giulio ; Alonso, María José ; Csaba, Noemi ; de la Fuente, María ; Préat, Véronique. A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease.. In: Colloids and Surfaces B: Biointerfaces, Vol. 143, p. 327-335 (2016). doi:10.1016/j.colsurfb.2016.03.038.

http://hdl.handle.net/2078.1/174760

Ibacache, Juana Andrea ; Valderrama, Jaime A ; Arancibia, Verónica ; Theoduloz, Cristina ; Muccioli, Giulio ; Benites, Julio. Antiproliferative activity of new 6-bromine derivatives of 7-anilino-1-arylisoquinolinequinones. In: Journal of the Chilean Chemical Sociaty, Vol. 61, no. 4, p. 3191-3194 (2016). doi:10.4067/S0717-97072016000400008.

http://hdl.handle.net/2078.1/186002

Caruano, Joséphine ; Muccioli, Giulio ; Robiette, Raphaël. Biologically active γ-lactams: synthesis and natural sources. In: Organic & Biomolecular Chemistry, Vol. 14, no.43, p. 10134-10156 (2016). doi:10.1039/C6OB01349J.

http://hdl.handle.net/2078.1/178217

Guada ramirez, Melissa ; Beloqui Garcia, Ana ; Al Houayek, Mireille ; Muccioli, Giulio ; Dios-Viéitez, Maria del Carmen ; Préat, Véronique ; Blanco-Prieto, Maria J.. Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease. In: International Journal of Pharmaceutics, Vol. 503, no. 1-2, p. 196-198 (2016). doi:10.1016/j.ijpharm.2016.03.012.

http://hdl.handle.net/2078.1/175320

Masquelier, Julien ; Muccioli, Giulio. Development and validation of a specific and sensitive HPLC-ESI-MS method for quantification of lysophosphatidylinositols and evaluation of their levels in mice tissues. In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 126, no.1, p. 132-140 (2016). doi:10.1016/j.jpba.2016.04.011.

http://hdl.handle.net/2078.1/175318

Mutemberezi, Valentin ; Masquelier, Julien ; Guillemot-Legris, Owein ; Muccioli, Giulio. Development and validation of an HPLC-MS method for the simultaneous quantification of key oxysterols, endocannabinoids, and ceramides: variations in metabolic syndrome. In: Analytical and Bioanalytical Chemistry, Vol. 408, no. 3, p. 733-745 (2016). doi:10.1007/s00216-015-9150-z.

http://hdl.handle.net/2078.1/173256

Guillemot-Legris, Owein ; Masquelier, Julien ; Everard, Amandine ; Cani, Patrice D. ; Al Houayek, Mireille ; Muccioli, Giulio. High-fat diet feeding differentially affects the development of inflammation in the central nervous system. In: Journal of Neuroinflammation, Vol. 13, no.1, p. 206 [1-11] (2016). doi:10.1186/s12974-016-0666-8.

http://hdl.handle.net/2078.1/180713

Gerin, Isabelle ; Ury, Benoît ; Breloy, Isabelle ; Bouchet-Seraphin, Céline ; Bolsée, Jennifer ; Halbout, Mathias ; Graff, Julie ; Vertommen, Didier ; Muccioli, Giulio ; Seta, Nathalie ; Cuisset, Jean-Marie ; Dabaj, Ivana ; Quijano-Roy, Susana ; Grahn, Ammi ; Van Schaftingen, Emile ; Bommer, Guido. ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan. In: Nature Communications, Vol. 7, no. 1, p. 11534 [1-15] (2016). doi:10.1038/ncomms11534.

http://hdl.handle.net/2078.1/175322

Mignion, Lionel ; Danhier, Pierre ; Magat, Julie ; Porporato, Paolo ; Masquelier, Julien ; Grégoire, Vincent ; Muccioli, Giulio ; Sonveaux, Pierre ; Gallez, Bernard ; Jordan, Bénédicte. Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.. In: International Journal of Cancer, Vol. 138, no. 8, p. 2043-2049 (2016). doi:10.1002/ijc.29932.

http://hdl.handle.net/2078.1/167746

Guillemot-Legris, Owein ; Mutemberezi, Valentin ; Cani, Patrice D. ; Muccioli, Giulio. Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma.. In: Scientific Reports, Vol. 6, p. 19694 [1-11] (2016). doi:10.1038/srep19694.

http://hdl.handle.net/2078.1/175108

Orefice, Nicola S. ; Al Houayek, Mireille ; Carotenuto, Antonio ; Montella, Silvana ; Barbato, Franscesco ; Comelli, Albert ; Calignano, Antonio ; Muccioli, Giulio ; Orefice, Giuseppe. Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis. In: Neurotherapeutics, Vol. 13, no. 2, p. 428-438 (2016). doi:10.1007/s13311-016-0420-z.

http://hdl.handle.net/2078.1/175321

Guillemot-Legris, Owein ; Mutemberezi, Valentin ; Muccioli, Giulio. Oxysterols in Metabolic Syndrome: From Bystander Molecules to Bioactive Lipids. In: Trends in Molecular Medicine, Vol. 22, no. 7, p. 594-614 (2016). doi:10.1016/j.molmed.2016.05.006.

http://hdl.handle.net/2078.1/175314

Mutemberezi, Valentin ; Guillemot-Legris, Owein ; Muccioli, Giulio. Oxysterols: From cholesterol metabolites to key mediators. In: Progress in Lipid Research, Vol. 64, p. 152-169 (2016). doi:10.1016/j.plipres.2016.09.002.

http://hdl.handle.net/2078.1/180714

Luo, Tian ; Loira Pastoriza, Cristina ; Patil, Harshad Padmanabh ; Ucakar, Bernard ; Muccioli, Giulio ; Bosquillon, Cynthia ; Vanbever, Rita. PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma.. In: Journal of Controlled Release, Vol. 239, p. 62-71 (2016). doi:10.1016/j.jconrel.2016.08.008.

http://hdl.handle.net/2078.1/176904

Lepannetier, Sophie ; Zanou, Bidossessi Nadège ; Yerna, Xavier ; Emeriau, Noémie ; Dufour, Inès ; Masquelier, Julien ; Muccioli, Giulio ; Tajeddine, Nicolas ; Gailly, Philippe. Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells.. In: Cell Calcium, Vol. 60, no. 6, p. 373-383 (2016). doi:10.1016/j.ceca.2016.09.002.

http://hdl.handle.net/2078.1/181507

Valderrama, Jaime ; Delgado, Virginia ; Sepúlveda, Sandra ; Benites, Julio ; Theoduloz, Cristina ; Buc Calderon, Pedro ; Muccioli, Giulio. Synthesis and Cytotoxic Activity on Human Cancer Cells of Novel Isoquinolinequinone–Amino Acid Derivatives. In: Molecules : a journal of synthetic organic and natural product chemistry, Vol. 21, no. 9, p. 1199 [1-14] (2016). doi:10.3390/molecules21091199.

http://hdl.handle.net/2078.1/181915

Geurts, Lucie ; Everard, Amandine ; Van Hul, Matthias ; Essaghir, Ahmed ; Duparc, Thibaut ; Matamoros, Sébastien ; Plovier, Hubert ; Castel, Julien ; Denis, Raphael G P ; Bergiers, Marie ; Druart, Céline ; Al Houayek, Mireille ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Demoulin, Jean-Baptiste ; Luquet, Serge ; Cani, Patrice D.. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. In: Nature Communications, Vol. 6, p. 6495 [1-15] (2015). doi:10.1038/ncomms7495.

http://hdl.handle.net/2078.1/162016

El Bakali, Jamal ; Muccioli, Giulio ; Body-Malapel, Mathilde ; Djouina, Madjid ; Klupsch, Frédérique ; Ghinet, Alina ; Barczyk, Amélie ; Renault, Nicolas ; Chavatte, Philippe ; Desreumaux, Pierre ; Lambert, Didier ; Millet, Régis. Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis. In: ACS Medicinal Chemistry Letters, Vol. 6, no.2, p. 198-203 (2015). doi:10.1021/ml500439x.

http://hdl.handle.net/2078.1/157082

Izzo, Angelo A ; Muccioli, Giulio ; Ruggieri, Michael R ; Schicho, Rudolf. Endocannabinoids and the Digestive Tract and Bladder in Health and Disease.. In: Handbook of Experimental Pharmacology, Vol. 231, p. 423-447 (2015). doi:10.1007/978-3-319-20825-1_15.

http://hdl.handle.net/2078.1/167582

Valderrama, Jaime A. ; Ríos, David ; Muccioli, Giulio ; Buc Calderon, Pedro ; Brito, Iván ; Benites, Julio. Hetero-annulation reaction between 2-acylnaphthoquinones and 2-aminobenzothiazoles. A new synthetic route to antiproliferative benzo[g]benzothiazolo[2,3-b]quinazoline-7,12-quinones. In: Tetrahedron Letters, Vol. 56, no.36, p. 5103-5105 (2015). doi:10.1016/j.tetlet.2015.07.034.

http://hdl.handle.net/2078.1/167598

Bosier, Barbara ; Doyen, Pierre ; Brolet, Amandine ; Muccioli, Giulio ; Ahmed, Eman ; Desmet, Nathalie ; Hermans, Emmanuel ; Deumens, Ronald. Inhibition of the regulator of G protein signalling RGS4 in the spinal cord decreases neuropathic hyperalgesia and restores cannabinoid CB1 receptor signalling.. In: British Journal of Pharmacology, Vol. 172, no.22, p. 5333-5346 (2015). doi:10.1111/bph.13324.

http://hdl.handle.net/2078.1/172491

Vandevelde, Nathalie ; Tulkens, Paul M. ; Muccioli, Giulio ; Van Bambeke, Françoise. Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms. In: Journal of Antimicrobial Chemotherapy, Vol. 70, no. 6, p. 1713-1726 (2015). doi:10.1093/jac/dkv032.

http://hdl.handle.net/2078.1/159375

Al Houayek, Mireille ; Bottemanne, Pauline ; Subramanian, Kumar V ; Lambert, Didier ; Makriyannis, Alexandros ; Cani, Patrice D. ; Muccioli, Giulio. N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis. In: The FASEB Journal, Vol. 29, no.2, p. 650-661 (2015). doi:10.1096/fj.14-255208.

http://hdl.handle.net/2078.1/157086

Bindels, Laure B. ; Neyrinck, Audrey M. ; Salazar Garzo, Nuria ; Taminiau, Bernard ; Druart, Céline ; Muccioli, Giulio ; François, Emmanuelle ; Blecker, Christophe ; Richel, Aurore ; Daube, Georges ; Mahillon, Jacques ; de Los Reyes-Gavilán, Clara G ; Cani, Patrice D. ; Delzenne, Nathalie M.. Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice. In: PLoS One, Vol. 10, no. 6, p. e0131009 [1-16] (2015). doi:10.1371/journal.pone.0131009.

http://hdl.handle.net/2078.1/162011

Caruano, Joséphine ; Feledziak, Marion ; Labar, Geoffray ; Michaux, Catherine ; Perpete, Eric ; Muccioli, Giulio ; Robiette, Raphaël ; Marchand-Brynaert, Jacqueline. (S)-1-(Pent-4’-enoyl)-4-(hydroxymethyl)-azetidin-2-one derivatives as inhibitors of human fatty acid amide hydrolase (hFAAH): synthesis, biological evaluation and molecular modelling. In: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 29, no. /, p. 654-662 (2014). doi:10.3109/14756366.2013.837900.

http://hdl.handle.net/2078.1/137070

Al Houayek, Mireille ; Muccioli, Giulio. COX-2-derived endocannabinoid metabolites as novel inflammatory mediators. In: Trends in Pharmacological Sciences, Vol. 35, no.6, p. 284-292 (2014). doi:10.1016/j.tips.2014.03.001.

http://hdl.handle.net/2078.1/145133

Al Houayek, Mireille ; Masquelier, Julien ; Muccioli, Giulio. Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy. In: Drug Discovery Today, Vol. 19, no. 3, p. 295-304 (2014). doi:10.1016/j.drudis.2013.07.009.

http://hdl.handle.net/2078.1/141045

Reychler, Gregory ; Aubriot, Anne-Sophie ; Masquelier, Julien ; Muccioli, Giulio ; Liistro, Giuseppe. Effect of drug-targeting nebulization on lung delivery. In: Archivos de Bronconeumologia, Vol. 50, no. 3, p. 500-501 (2014). doi:10.1016/j.arbres.2013.10.014.

http://hdl.handle.net/2078.1/141050

Al Houayek, Mireille ; Muccioli, Giulio. Harnessing the anti-inflammatory potential of palmitoylethanolamide.. In: Drug discovery today, , no.1-8 (2014). doi:10.1016/j.drudis.2014.06.007 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/145135

Everard, Amandine ; Geurts, Lucie ; Caesar, Robert ; Van Hul, Matthias ; Matamoros, Sébastien ; Duparc, Thibaut ; Denis, Raphael G P ; Cochez, Perrine ; Pierard, Florian ; Castel, Julien ; Bindels, Laure B. ; Plovier, Hubert ; Robine, Sylvie ; Muccioli, Giulio ; Renauld, Jean-Christophe ; Dumoutier, Laure ; Delzenne, Nathalie M. ; Luquet, Serge ; Bäckhed, Fredrik ; Cani, Patrice D.. Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status. In: Nature Communications, Vol. 5, no. 1, p. 5648 [1-12] (2014). doi:10.1038/ncomms6648.

http://hdl.handle.net/2078.1/156590

Ibacache, Juana Andrea ; Delgado, Virginia ; Benites, Julio ; Theoduloz, Cristina ; Arancibia, Verónica ; Muccioli, Giulio ; Valderrama, Jaime A. Synthesis, half-wave potentials and antiproliferative activity of 1-aryl-substituted aminoisoquinolinequinones.. In: Molecules (Basel, Switzerland), Vol. 19, no.1, p. 726-39 (2014). doi:10.3390/molecules19010726.

http://hdl.handle.net/2078.1/141047

Tourteau, Aurélien ; Andrzejak, Virginie ; Body-Malapel, Mathilde ; Lemaire, Lucas ; Lemoine, Amélie ; Mansouri, Roxane ; Djouina, Madjid ; Renault, Nicolas ; El Bakali, Jamal ; Desreumaux, Pierre ; Muccioli, Giulio ; Lambert, Didier M ; Chavatte, Philippe ; Rigo, Benoît ; Leleu-Chavain, Natascha ; Millet, Régis. 3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.. In: Bioorganic & medicinal chemistry, Vol. 21, no. 17, p. 5383-94 (2013). doi:10.1016/j.bmc.2013.06.010.

http://hdl.handle.net/2078.1/141051

Beloqui Garcia, Ana ; Coco, Régis ; Al Houayek, Mireille ; Solinís, María Ángeles ; Rodríguez-Gascón, Alicia ; Muccioli, Giulio ; Préat, Véronique. Budesonide-loaded nanostructured lipid carriers reduce inflammation in murine DSS-induced colitis. In: International Journal of Pharmaceutics, Vol. 454, no. 2, p. 775-783 (2013). doi:10.1016/j.ijpharm.2013.05.017.

http://hdl.handle.net/2078.1/131923

Geurts, Lucie ; Muccioli, Giulio ; Delzenne, Nathalie M. ; Cani, Patrice D.. Chronic endocannabinoid system stimulation induces muscle macrophage and lipid accumulation in type 2 diabetic mice independently of metabolic endotoxaemia. In: PLoS One, Vol. 8, no.2, p. e55963 [1-10] (2013). doi:10.1371/journal.pone.0055963.

http://hdl.handle.net/2078.1/131551

Everard, Amandine ; Belzer, Clara ; Geurts, Lucie ; Ouwerkerk, Janneke P ; Druart, Céline ; Bindels, Laure B. ; Guiot, Yves ; Derrien, Muriel ; Muccioli, Giulio ; Delzenne, Nathalie M. ; de Vos, Willem M ; Cani, Patrice D.. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. In: Proceedings of the National academy of sciences of the United States of America, Vol. 110, no.22, p. 9066-9071 (2013). doi:10.1073/pnas.1219451110.

http://hdl.handle.net/2078.1/131542

Arenas, Paola ; Peña, Andrés ; Ríos, David ; Benites, Julio ; Muccioli, Giulio ; Buc Calderon, Pedro ; Valderrama, Jaime A. Eco-friendly synthesis and antiproliferative evaluation of some oxygen substituted diaryl ketones. In: Molecules, Vol. 18, no. 8, p. 9818-9832 (2013). doi:10.3390/molecules18089818.

http://hdl.handle.net/2078.1/145225

Al Houayek, Mireille ; Masquelier, Julien ; Cani, Patrice D. ; Lambert, Didier M. ; Muccioli, Giulio. Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. In: Proceedings of the National academy of sciences of the United States of America, Vol. 110, no.43, p. 17558-17563 (2013). doi:10.1073/pnas.1314017110.

http://hdl.handle.net/2078.1/134706

Bosier, Barbara ; Muccioli, Giulio ; Lambert, Didier. The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB(1) and FAAH-independent mechanisms. In: British Journal of Pharmacology, Vol. 169, no. 4, p. 794-807 (2013). doi:10.1111/j.1476-5381.2012.02208.x.

http://hdl.handle.net/2078.1/119601

El Bakali, Jamal ; Gilleron, Pauline ; Body-Malapel, Mathilde ; Mansouri, Roxane ; Muccioli, Giulio ; Djouina, Madjid ; Barczyk, Amélie ; Klupsch, Frédérique ; Andrzejak, Virginie ; Lipka, Emmanuelle ; Furman, Christophe ; Lambert, Didier ; Chavatte, Philippe ; Desreumaux, Pierre ; Millet, Régis. 4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis. In: Journal of Medicinal Chemistry, Vol. 55, no. 20, p. 8948-8952 (2012). doi:10.1021/jm3008568.

http://hdl.handle.net/2078.1/141066

Bosier, Barbara ; Muccioli, Giulio ; Mertens, Birgit ; Sarre, Sophie ; Michotte, Yvette ; Lambert, Didier M ; Hermans, Emmanuel. Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.. In: Neuropharmacology, Vol. 62, no. 7, p. 2328-2336 (2012). doi:10.1016/j.neuropharm.2012.02.003.

http://hdl.handle.net/2078.1/119604

Matuszak, Nicolas ; Hamtiaux, Laurie ; Baldeyroux, Brigitte ; Muccioli, Giulio ; Poupaert, Jacques H ; Lansiaux, Amélie ; Lambert, Didier M. Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth.. In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 45, no. 3, p. 263-71 (2012). doi:10.1016/j.ejps.2011.11.011.

http://hdl.handle.net/2078.1/141071

Bindels, Laure B. ; Porporato, Paolo ; Dewulf, Evelyne ; Verrax, Julien ; Neyrinck, Audrey M. ; Martin, J C ; Scott, K P ; Buc Calderon, Pedro ; Feron, Olivier ; Muccioli, Giulio ; Sonveaux, Pierre ; Cani, Patrice D. ; Delzenne, Nathalie M.. Gut microbiota-derived propionate reduces cancer cell proliferation in the liver. In: The British journal of cancer, Vol. 107, no. 8, p. 1337-1344 (2012). doi:10.1038/bjc.2012.409.

http://hdl.handle.net/2078.1/118969

Feledziak, Marion ; Lambert, Didier, M. ; Marchand-Brynaert, Jacqueline ; Muccioli, Giulio. Inhibitors of the Endocannabinoid-Degrading Enzymes, or how to Increase Endocannabinoid's Activity by Preventing their Hydrolysis. In: Recent Patents on C N S Drug Discovery, Vol. 7, no.1, p. 49-70 (2012). doi:10.2174/157488912798842223.

http://hdl.handle.net/2078.1/125508

Kapanda, Coco N ; Masquelier, Julien ; Labar, Geoffray ; Muccioli, Giulio ; Poupaert, Jacques H ; Lambert, Didier M. Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.. In: Journal of medicinal chemistry, Vol. 55, no. 12, p. 5774-83 (2012). doi:10.1021/jm3006004.

http://hdl.handle.net/2078.1/141068

Hamtiaux, Laurie ; Masquelier, Julien ; Muccioli, Giulio ; Bouzin, Caroline ; Feron, Olivier ; Gallez, Bernard ; Lambert, Didier. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action. In: BMC Cancer, Vol. 12, p. 92 [1-12] (2012). doi:10.1186/1471-2407-12-92.

http://hdl.handle.net/2078/119829

Al Houayek, Mireille ; Muccioli, Giulio. The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. In: Trends in Molecular Medicine, Vol. 18, no. 10, p. 615-625 (2012). doi:10.1016/j.molmed.2012.07.009.

http://hdl.handle.net/2078.1/141217

Geurts, Lucie ; Lazarevic, Vladimir ; Derrien, Muriel ; Everard, Amandine ; Van Roye, Marie ; Knauf, Claude ; Valet, Philippe ; Girard, Myriam ; Muccioli, Giulio ; François, Patrice ; de Vos, Willem M. ; Schrenzel, Jacques ; Delzenne, Nathalie M. ; Cani, Patrice D.. Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice : impact on apelin regulation in adipose tissue.. In: Frontiers in Microbiology, Vol. 2, p. [1-17] (2011). doi:10.3389/fmicb.2011.00149.

http://hdl.handle.net/2078.1/104558

Marrs, William R. ; Horne, Eric A. ; Ortega-Gutierrez, Silvia ; Cisneros, Jose Antonio ; Xu, Cong ; Lin, Yi Hsing ; Muccioli, Giulio ; Lopez-Rodriguez, Maria L. ; Stella, Nephi. Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. In: Journal of Biological Chemistry, Vol. 286, no. 33, p. 28723-8 (2011). doi:10.1074/jbc.M110.202853.

http://hdl.handle.net/2078.1/105983

Pachikian, Barbara D. ; Essaghir, Ahmed ; Demoulin, Jean-Baptiste ; Neyrinck, Audrey M. ; Catry, Emilie ; De Backer, Fabienne ; Dejeans, Nicolas ; Dewulf, Evelyne ; Sohet, Florence ; Portois, Laurence ; Deldicque, Louise ; Molendi-Coste, Olivier ; Leclercq, Isabelle ; Francaux, Marc ; Carpentier, Yvon A ; Foufelle, Fabienne ; Muccioli, Giulio ; Cani, Patrice D. ; Delzenne, Nathalie M.. Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice : genomic analysis of cellular targets.. In: PLoS One, Vol. 6, no. 8, p. e23365 (2011). doi:10.1371/journal.pone.0023365.

http://hdl.handle.net/2078.1/95891

Hamtiaux, Laurie ; Hansoulle, Laurie ; Dauguet, Nicolas ; Muccioli, Giulio ; Gallez, Bernard ; Lambert, Didier. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. In: PLoS One, Vol. 6, no. 10, p. [1-14] (2011). doi:10.1371/journal.pone.0026823.

http://hdl.handle.net/2078.1/105968

Al Houayek, Mireille ; Lambert, Didier ; Delzenne, Nathalie M. ; Cani, Patrice D. ; Muccioli, Giulio. Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. In: The FASEB Journal, Vol. 25, no. 8, p. 2711-2721 (2011). doi:10.1096/fj.10-176602.

http://hdl.handle.net/2078.1/104024

Dewulf, Evelyne ; Cani, Patrice D. ; Neyrinck, Audrey M. ; Possemiers, Sam ; Van Holle, Ann ; Muccioli, Giulio ; Deldicque, Louise ; Bindels, Laure B. ; Pachikian, Barbara D. ; Sohet, Florence ; Mignolet, Eric ; Francaux, Marc ; Larondelle, Yvan ; Delzenne, Nathalie M.. Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice.. In: The Journal of Nutritional Biochemistry, Vol. 22, no. 8, p. 712-722 (2011). doi:10.1016/j.jnutbio.2010.05.009.

http://hdl.handle.net/2078.1/68589

Duparc, Thibaut ; Naslain, Damien ; Colom, André ; Muccioli, Giulio ; Massaly, Nicolas ; Delzenne, Nathalie M. ; Valet, Philippe ; Cani, Patrice D. ; Knauf, Claude. Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus.. In: Antioxidants & Redox Signaling, Vol. 14, no. 3, p. 415-423 (2011). doi:10.1089/ars.2010.3330.

http://hdl.handle.net/2078.1/104258

Thabuis, Clémentine ; Destaillats, Frédéric ; Lambert, Didier ; Muccioli, Giulio ; Maillot, Matthieu ; Harach, Touafiq ; Tissot-Favre, Delphine ; Martin, Jean-Charles. Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice. In: Journal of Lipid Research, Vol. 52, no. 7, p. 1373-82 (2011). doi:10.1194/jlr.M013391.

http://hdl.handle.net/2078.1/106001

Sexton, Michelle ; Woodruff, Grace ; Horne, Eric A. ; Lin, Yi Hsing ; Muccioli, Giulio ; Bai, Mingfeng ; Stern, Eric ; Bornhop, Darryl J. ; Stella, Nephi. NIR-mbc94, a fluorescent ligand that binds to endogenous CB(2) receptors and is amenable to high-throughput screening. In: Chemistry & Biology, Vol. 18, no. 5, p. 563-568 (2011). doi:10.1016/j.chembiol.2011.02.016.

http://hdl.handle.net/2078.1/105997

Andrzejak, Virginie ; Muccioli, Giulio ; Body-Malapel, Mathilde ; El Bakali, Jamal ; Djouina, Madjid ; Renault, Nicolas ; Chavatte, Philippe ; Desreumaux, Pierre ; Lambert, Didier ; Millet, Régis. New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis. In: Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 19, no. 12, p. 3777-3786 (2011). doi:10.1016/j.bmc.2011.04.057.

http://hdl.handle.net/2078.1/105699

Everard, Amandine ; Lazarevic, Vladimir ; Derrien, Muriel ; Girard, Myriam ; Muccioli, Giulio ; Neyrinck, Audrey M. ; Possemiers, Sam ; Van Holle, Ann ; François, Patrice ; de Vos, Willem M ; Delzenne, Nathalie M. ; Schrenzel, Jacques ; Cani, Patrice D.. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. In: Diabetes, Vol. 60, no. 11, p. 2775-2786 (2011). doi:10.2337/db11-0227.

http://hdl.handle.net/2078.1/104554

Feledziak, Marion ; Muccioli, Giulio ; Lambert, Didier ; Marchand-Brynaert, Jacqueline. SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH) : evidence of a nonhydrolytic process. In: Journal of Medicinal Chemistry, Vol. 54, no. 19, p. 6812-6823 (2011). doi:10.1021/jm200723m.

http://hdl.handle.net/2078.1/105950

Evens, Nele ; Vandeputte, Caroline ; Muccioli, Giulio ; Lambert, Didier ; Baekelandt, Veerle ; Verbruggen, Alfons M. ; Debyser, Zeger ; Van Laere, Koen ; Bormans, Guy M.. Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging. In: Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 19, no. 15, p. 4499-4505 (2011). doi:10.1016/j.bmc.2011.06.033.

http://hdl.handle.net/2078.1/105757

El Bakali, Jamal ; Muccioli, Giulio ; Renault, Nicolas ; Pradal, Delphine ; Body-Malapel, Mathilde ; Djouina, Madjid ; Hamtiaux, Laurie ; Andrzejak, Virginie ; Desreumaux, Pierre ; Chavatte, Philippe ; Lambert, Didier ; Millet, Régis. 4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands : structural insights into the design of a novel inverse agonist series.. In: Journal of Medicinal Chemistry, Vol. 53, no. 22, p. 7918-7931 (2010). doi:10.1021/jm100286k.

http://hdl.handle.net/2078.1/106428

De Wael, Frédéric ; Muccioli, Giulio ; Lambert, Didier ; Sergent, Thérèse ; Schneider, Yves-Jacques ; Rees, Jean-François ; Marchand-Brynaert, Jacqueline. Chemistry around imidazopyrazine and ibuprofen : discovery of novel fatty acid amide hydrolase (FAAH) inhibitors. In: European Journal of Medicinal Chemistry, Vol. 45, no. 9, p. 3564-3574 (2010). doi:10.1016/j.ejmech.2010.04.040.

http://hdl.handle.net/2078.1/32578

Muccioli, Giulio. Endocannabinoid biosynthesis and inactivation, from simple to complex.. In: Drug Discovery Today, Vol. 15, no. 11-12, p. 474-483 (2010). doi:10.1016/j.drudis.2010.03.007.

http://hdl.handle.net/2078.1/30702

Bosier, Barbara ; Muccioli, Giulio ; Hermans, Emmanuel ; Lambert, Didier. Functionally selective cannabinoid receptor signalling : therapeutic implications and opportunities. In: Biochemical Pharmacology, Vol. 80, no. 1, p. 1-12 (2010). doi:10.1016/j.bcp.2010.02.013.

http://hdl.handle.net/2078.1/33886

Collard, François ; Stroobant, Vincent ; Lamosa, Pedro ; Kapanda Nankwa, Coco ; Lambert, Didier ; Muccioli, Giulio ; Poupaert, Jacques ; Opperdoes, Frederik ; Van Schaftingen, Emile. Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.. In: Journal of Biological Chemistry, Vol. 285, no. 39, p. 29826-29833 (2010). doi:10.1074/jbc.M110.152629.

http://hdl.handle.net/2078.1/33133

Wyffels, Leonie ; Muccioli, Giulio ; Kapanda Nankwa, Coco ; Labar, Geoffray ; De Bruyne, Sylvie ; De Vos, Filip ; Lambert, Didier. PET imaging of fatty acid amide hydrolase in the brain : synthesis and biological evaluation of an C-11-labelled URB597 analogue. In: Nuclear Medicine and Biology, Vol. 37, no. 5, p. 665-75 (2010). doi:10.1016/j.nucmedbio.2010.03.009.

http://hdl.handle.net/2078.1/33726

Muccioli, Giulio ; Naslain, Damien ; Bäckhed, Fredrik ; Reigstad, Christopher S. ; Lambert, Didier ; Delzenne, Nathalie M. ; Cani, Patrice D.. The endocannabinoid system links gut microbiota to adipogenesis. In: Molecular Systems Biology, Vol. 6, p. 392 [1-15] (2010). doi:10.1038/msb.2010.46.

http://hdl.handle.net/2078.1/33126

Marrs, William R. ; Blankman, Jacqueline L. ; Horne, Eric A. ; Thomazeau, Aurore ; Lin, Yi Hsing ; Coy, Jonathan ; Bodor, Agnes L. ; Muccioli, Giulio ; Hu, Sherry Shu-Jung ; Woodruff, Grace ; Fung, Susan ; Lafourcade, Mathieu ; Alexander, Jessica P. ; Long, Jonathan Z. ; Li, Weiwei ; Xu, Cong ; Moeller, Thomas ; Mackie, Ken ; Manzoni, Olivier J. ; Cravatt, Benjamin F. ; Stella, Nephi. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. In: Nature Neuroscience, Vol. 13, no. 8, p. 951-7 (2010). doi:10.1038/nn.2601.

http://hdl.handle.net/2078.1/33628

Feledziak, Marion ; Michaux, Catherine ; Urbach, Allan ; Labar, Geoffray ; Muccioli, Giulio ; Lambert, Didier ; Marchand-Brynaert, Jacqueline. Beta-lactams derived from a carbapenem chiron are selective inhibitors of human fatty acid amide hydrolase versus human monoacylglycerol lipase. In: Journal of Medicinal Chemistry, Vol. 52, no. 22, p. 7054-7068 (2009). doi:10.1021/jm9008532.

http://hdl.handle.net/2078.1/28546

Kapanda, Coco N. ; Muccioli, Giulio ; Labar, Geoffray ; Poupaert, Jacques ; Lambert, Didier. Bis(dialkylaminethiocarbonyl)disulfides as Potent and Selective Monoglyceride Lipase Inhibitors. In: Journal of Medicinal Chemistry, Vol. 52, no. 22, p. 7310-7314 (2009). doi:10.1021/jm901323s.

http://hdl.handle.net/2078.1/28544

Cani, Patrice D. ; Possemiers, S. ; Van de Wiele, T. ; Guiot, Yves ; Everard, Amandine ; Rottier, O. ; Geurts, Lucie ; Naslain, Damien ; Neyrinck, Audrey M. ; Lambert, Didier ; Muccioli, Giulio ; Delzenne, Nathalie M.. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. In: Gut, Vol. 58, no. 8, p. 1091-1103 (2009). doi:10.1136/gut.2008.165886.

http://hdl.handle.net/2078.1/27380

Muccioli, Giulio ; Sia, Angela ; Muchowski, Paul J. ; Stella, Nephi. Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae.. In: PLoS One, Vol. 4, no. 6, p. e5942 (2009). doi:10.1371/journal.pone.0005942.

http://hdl.handle.net/2078.1/106608

Kapanda Nankwa, Coco ; Muccioli, Giulio ; Labar, Geoffray ; Draoui, Nihed ; Lambert, Didier ; Poupaert, Jacques. Search for monoglyceride lipase inhibitors : synthesis and screening of arylthioamides derivatives. In: Medicinal Chemistry Research, Vol. 18, no. 4, p. 243-254 (2009). doi:10.1007/s00044-008-9123-2.

http://hdl.handle.net/2078.1/35613

Evens, Nele ; Muccioli, Giulio ; Houbrechts, Nele ; Lambert, Didier ; Verbruggen, Alfons M. ; Van Laere, Koen ; Bormans, Guy M.. Synthesis and biological evaluation of carbon-11-and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging. In: Nuclear Medicine and Biology, Vol. 36, no. 4, p. 455-465 (2009). doi:10.1016/j.nucmedbio.2009.01.009.

http://hdl.handle.net/2078.1/35555

Matuszak, Nicolas ; Muccioli, Giulio ; Labar, Geoffray ; Lambert, Didier. Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. In: Journal of Medicinal Chemistry, Vol. 52, no. 23, p. 7410-7420 (2009). doi:10.1021/jm900461w.

http://hdl.handle.net/2078.1/22828

Wyffels, Leonie ; Muccioli, Giulio ; De Bruyne, Sylvie ; Moerman, Lieselotte ; Sambre, Johan ; Lambert, Didier ; De Vos, Filip. Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. In: Journal of Medicinal Chemistry, Vol. 52, no. 15, p. 4613-4622 (2009). doi:10.1021/jm900324e.

http://hdl.handle.net/2078.1/35421

Urbach, Allan ; Muccioli, Giulio ; Stern, Eric ; Lambert, Didier ; Marchand-Brynaert, Jacqueline. 3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitors.. In: Bioorganic & Medicinal Chemistry Letters, Vol. 18, no. 14, p. 4163-4167 (2008). doi:10.1016/j.bmcl.2008.05.081.

http://hdl.handle.net/2078.1/12696

Muccioli, Giulio ; Stella, Nephi. An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. In: Analytical Biochemistry, Vol. 373, no.2, p. 220-228 (2008). doi:10.1016/j.ab.2007.09.030.

http://hdl.handle.net/2078.1/157083

Muccioli, Giulio ; Labar, Geoffray ; Lambert, Didier. CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. In: ChemBioChem : a European journal of chemical biology, Vol. 9, no. 16, p. 2704-2710 (2008). doi:10.1002/cbic.200800428.

http://hdl.handle.net/2078.1/19641

Gallienne, Estelle ; Muccioli, Giulio ; Lambert, Didier ; Shipman, Michael. Microwave-assisted four-component reaction for the synthesis of a monothiohydantoin inhibitor of a fatty acid amide hydrolase. In: Tetrahedron Letters, Vol. 49, no. 46, p. 6495-6497 (2008). doi:10.1016/j.tetlet.2008.08.100.

http://hdl.handle.net/2078.1/37107

Hoet, Sara ; Pieters, Luc ; Muccioli, Giulio ; Habib Jiwan, Jean-Louis ; Opperdoes, Frederik ; Quetin-Leclercq, Joëlle. Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.. In: Journal of Natural Products, Vol. 70, no. 8, p. 1360-1363 (2007). doi:10.1021/np070038q.

http://hdl.handle.net/2078.1/11035

Muccioli, Giulio. Blocking the cannabinoid receptors: Drug candidates and therapeutic promises. In: Chemistry & Biodiversity, Vol. 4, no. 8, p. 1805-1827 (2007). doi:10.1002/cbdv.200790153.

http://hdl.handle.net/2078.1/37358

Labar, Geoffray ; Bauvois, Cedric ; Muccioli, Giulio ; Wouters, Johan ; Lambert, Didier. Disulfiram is an inhibitor of human purified monoacylglycerol lipase, the enzyme regulating 2-arachidonoylglycerol signaling. In: ChemBioChem, Vol. 8, no. 11, p. 1293-1297 (2007). doi:10.1002/cbic.200700139.

http://hdl.handle.net/2078.1/11009

Lambert, Didier ; Muccioli, Giulio. Endocannabinoids and related N-acylethanolamines in the control of appetite and energy metabolism: emergence of new molecular players.. In: Current opinion in clinical nutrition and metabolic care, Vol. 10, no. 6, p. 735-744 (2007). doi:10.1097/MCO.0b013e3282f00061.

http://hdl.handle.net/2078.1/11229

Muccioli, Giulio ; Xu, Cong ; Odah, Emma ; Cudaback, Eiron ; Antonio Cisneros, Jose ; Lambert, Didier ; Lopez Rodriguez, Maria Luz ; Bajjalieh, Sandra ; Stella, Nephi. Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells. In: The Journal of Neuroscience, Vol. 27, no. 11, p. 2883-9 (2007). doi:10.1523/JNEUROSCI.4830-06.2007.

http://hdl.handle.net/2078.1/37698

Stern, Eric ; Muccioli, Giulio ; Bosier, Barbara ; Hamtiaux, Laurie ; Millet, Regis ; Poupaert, Jacques ; Henichart, Jean-Pierre ; Depreux, Patrick ; Goossens, Jean-Francois ; Lambert, Didier. Pharmacomodulations around the 4-oxo-1,4-dihydroquinoline-3-carboxamides, a class of potent CB2-selective cannabinoid receptor ligands: Consequences in receptor affinity and functionality. In: Journal of Medicinal Chemistry, Vol. 50, no. 22, p. 5471-84 (2007). doi:10.1021/jm070387h.

http://hdl.handle.net/2078.1/37270

Philip, Ashok E. ; Poupaert, Jacques ; Cheve, Gwenael ; Muccioli, Giulio ; Lambert, Didier ; McCurdy, Christopher R.. Structure-activity relationship of phenytoinergic antiepileptic drugs related to ameltolide. In: Medicinal Chemistry Research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Vol. 16, no. 3, p. 130-135 (2007). doi:10.1007/s00044-007-9016-9.

http://hdl.handle.net/2078.1/36853

Michaux, Catherine ; Muccioli, Giulio ; Lambert, Didier ; Wouters, Johan. Binding mode of new (thio)hydantoin inhibitors of fatty acid amide hydrolase: comparison with two original compounds, OL-92 and JP104. In: Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 16, no. 18, p. 4772-4776 (2006). doi:10.1016/j.bmcl.2006.06.087.

http://hdl.handle.net/2078.1/141075

Muccioli, Giulio ; Lambert, Didier. Latest advances in cannabinoid receptor antagonists and inverse agonists. In: Expert Opinion on Therapeutic Patents, Vol. 16, no. 10, p. 1405-1423 (2006). doi:10.1517/13543776.16.10.1405.

http://hdl.handle.net/2078.1/38222

Stern, Eric ; Muccioli, Giulio ; Millet, R ; Goossens, JF ; Farce, A ; Chavatte, P ; Poupaert, Jacques ; Lambert, Didier ; Depreux, P. ; Hénichart, Jean-Pierre. Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: Synthesis, pharmacological properties and molecular modeling. In: Journal of Medicinal Chemistry, Vol. 49, no. 1, p. 70-79 (2006). doi:10.1021/jm050467q.

http://hdl.handle.net/2078.1/38710

Muccioli, Giulio ; Fazio, Nicola ; Scriba, Gerhard K E ; Poppitz, Wolfgang ; Cannata, Fabio ; Poupaert, Jacques ; Wouters, Johan ; Lambert, Didier. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates.. In: Journal of Medicinal Chemistry, Vol. 49, no. 1, p. 417-425 (2006). doi:10.1021/jm050977k.

http://hdl.handle.net/2078.1/10442

Muccioli, Giulio ; Wouters, Johan ; Charlier, Caroline ; Scriba, Gerhard K E ; Pizza, Teresa ; Di Pace, Pierluigi ; De Martino, Paolo ; Poppitz, Wolfgang ; Poupaert, Jacques ; Lambert, Didier. Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: characterization of new CB1 cannabinoid receptor inverse agonists/antagonists.. In: Journal of medicinal chemistry, Vol. 49, no. 3, p. 872-82 (2006). doi:10.1021/jm050484f.

http://hdl.handle.net/2078.1/10469

Muccioli, Giulio ; Wouters, Johan ; Scriba, Gerhard K E ; Poppitz, Wolfgang ; Poupaert, Jacques ; Lambert, Didier. 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.. In: Journal of medicinal chemistry, Vol. 48, no. 23, p. 7486-90 (2005). doi:10.1021/jm0503906.

http://hdl.handle.net/2078.1/10384

Muccioli, Giulio ; Lambert, Didier. Current knowledge on the antagonists and inverse agonists of cannabinoid receptors.. In: Current medicinal chemistry, Vol. 12, no. 12, p. 1361-94 (2005). doi:10.2174/0929867054020891.

http://hdl.handle.net/2078.1/10233

Gbaguidi, F. ; Muccioli, Giulio ; Accrombessi, Georges C. ; Moudachirou, M. ; Quetin-Leclercq, Joëlle. Densitometric HPTLC quantification of 2-azaanthraquinone isolated from Mitracarpus scaber and antimicrobial activity against Dermatophilus congolensis. In: Journal of Planar Chromatography - Modern TLC, Vol. 18, no. 105, p. 377-379 (2005). doi:10.1556/JPC.18.2005.5.8.

http://hdl.handle.net/2078.1/38997

Muccioli, Giulio ; Martin, Diana ; Scriba, Gerhard K E ; Poppitz, Wolfgang ; Poupaert, Jacques ; Wouters, Johan ; Lambert, Didier. Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation.. In: Journal of medicinal chemistry, Vol. 48, no. 7, p. 2509-17 (2005). doi:10.1021/jm049263k.

http://hdl.handle.net/2078.1/10150

Govaerts, Sophie ; Muccioli, Giulio ; Hermans, Emmanuel ; Lambert, Didier. Characterization of the pharmacology of imidazolidinedione derivatives at cannabinoid CB1 and CB2 receptors.. In: European Journal of Pharmacology, Vol. 495, no. 1, p. 43-53 (2004). doi:10.1016/j.ejphar.2004.05.023.

http://hdl.handle.net/2078.1/9888

Muccioli, Giulio ; Poupaert, Jacques ; Wouters, Johan ; Norberg, Bernadette ; Poppitz, Wolfgang ; Scriba, Gerhard K. E. ; Lambert, Didier. A rapid and efficient microwave-assisted synthesis of hydantoins and thiohydantoins. In: Tetrahedron, Vol. 59, no. 8, p. 1301-1307 (2003). doi:10.1016/S0040-4020(03)00033-4.

http://hdl.handle.net/2078.1/41451

Muccioli, Giulio ; Wouters, Johan ; Poupaert, Jacques ; Norberg, Bernadette ; Poppitz, Wolfgang ; Scriba, Gerhard K E ; Lambert, Didier. Versatile access to benzhydryl-phenylureas through an unexpected rearrangement during microwave-enhanced synthesis of hydantoins.. In: Organic letters, Vol. 5, no. 20, p. 3599-602 (2003). doi:10.1021/ol035282x.

http://hdl.handle.net/2078.1/9632

Al Houayek, Mireille ; Muccioli, Giulio. Pharmacological Aspects of Anandamide and 2-Arachidonoyglycerol as Bioactive Lipids. In: Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment, Elsevier, 2017, 616–629. 978-012800827-0;978-012800756-3. doi:10.1016/B978-0-12-800756-3.00074-0.

http://hdl.handle.net/2078.1/185914

Muccioli, Giulio. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as modulators of the endocannabinoid system, prom. : Lambert, Didier, 2005.

https://hdl.handle.net/2078.1/247928

Abdul Khaliq, Hafiz ; Al Houayek, Mireille ; Quetin-Leclercq, Joëlle ; Muccioli, Giulio. 5'AMP-activated protein kinase: an emerging target of phytochemicals to treat chronic inflammatory diseases.. In: Critical reviews in food science and nutrition, , p. [1-26] (2022). doi:10.1080/10408398.2022.2145264 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/270953

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle. Dereplication and Quantification of Major Compounds of L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages.. In: Molecules (Basel, Switzerland), Vol. 27, no.3, p. 963 [1-19] (2022). doi:10.3390/molecules27030963.

http://hdl.handle.net/2078.1/258760

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Neyts, Tanguy ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle. Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents. In: Toxicology Reports, Vol. 9, p. 1742-1753 (2022). doi:10.1016/j.toxrep.2022.09.004.

http://hdl.handle.net/2078.1/265887

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio. 25-Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice.. In: FASEB journal, Vol. 35, no.4, p. e21514 [1-19] (2021). doi:10.1096/fj.202002555R.

http://hdl.handle.net/2078.1/245667

Al Houayek, Mireille ; Ameraoui, Hafsa ; Muccioli, Giulio. Bioactive lipids in inflammatory bowel diseases - From pathophysiological alterations to therapeutic opportunities.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1866, no.2, p. 158854 [1-18] (2021). doi:10.1016/j.bbalip.2020.158854.

http://hdl.handle.net/2078.1/238828

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Ben Kouidar, Youssef ; Paquot, Adrien ; Muccioli, Giulio ; Al Houayek, Mireille. Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.. In: The FASEB Journal, Vol. 35, no. 4, p. e21411 [1-16] (2021). doi:10.1096/fj.202002468R.

http://hdl.handle.net/2078.1/241768

Bottemanne, Pauline ; Guillemot-Legris, Owein ; Paquot, Adrien ; Masquelier, Julien ; Malamas, Michael ; Makriyannis, Alexandros ; Al Houayek, Mireille ; Muccioli, Giulio. N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.. In: Neurotherapeutics, , p. [1-19] (2021). doi:10.1007/s13311-021-01074-x (Accepté/Sous presse).

http://hdl.handle.net/2078.1/252337

Al Houayek, Mireille ; Bannenberg, Gerard ; Muccioli, Giulio ; Norel, Xavier ; Yao, Chengcan ; Schebb, Nils Helge. Editorial-Special issue of the 7 European workshop on lipid mediators.. In: Prostaglandins & other lipid mediators, Vol. 148, p. 106421 [1-3] (2020). doi:10.1016/j.prostaglandins.2020.106421.

http://hdl.handle.net/2078.1/241764

Al Houayek, Mireille ; Stafberg, Linda ; Karlsson, Jessica ; Bergström, Sofia Halin ; Fowler, Christopher J. Effects of orthotopic implantation of rat prostate tumour cells upon components of the N-acylethanolamine and monoacylglycerol signalling systems: an mRNA study.. In: Scientific reports, Vol. 10, no. 1, p. 6314 (2020). doi:10.1038/s41598-020-63198-y.

http://hdl.handle.net/2078.1/241766

Orefice, Nicola S ; Guillemot-Legris, Owein ; Capasso, Rosanna ; Bottemanne, Pauline ; Hantraye, Philippe ; Caraglia, Michele ; Orefice, Giuseppe ; Al Houayek, Mireille ; Muccioli, Giulio. miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions.. In: eLife, Vol. 9, p. e56916 [1-25] (2020). doi:10.7554/eLife.56916.

http://hdl.handle.net/2078.1/238833

Al Houayek, Mireille ; Boldrup, Linda ; Fowler, Christopher J.. Altered mRNA Expression of Genes Involved in Endocannabinoid Signalling in Squamous Cell Carcinoma of the Oral Tongue. In: Cancer Investigation, Vol. 37, no. 8, p. 327-338 (2019). doi:10.1080/07357907.2019.1638394.

http://hdl.handle.net/2078.1/225643

Guillemot-Legris, Owein ; Mutemberezi, Valentin ; Buisseret, Baptiste ; Paquot, Adrien ; Palmieri, Vittoria ; Bottemanne, Pauline ; Lemaire, Julien ; Rahier, Jean-François ; Al Houayek, Mireille ; Muccioli, Giulio. Colitis alters oxysterol metabolism and is affected by 4β-hydroxycholesterol administration.. In: Journal of Crohn's & colitis, Vol. 13, no. 2, p. 218-229 (2019). doi:10.1093/ecco-jcc/jjy157.

http://hdl.handle.net/2078.1/204079

Buisseret, Baptiste ; Al Houayek, Mireille ; Guillemot-Legris, Owein ; Muccioli, Giulio. Endocannabinoid and Prostanoid Crosstalk in Pain. In: Trends in Molecular Medicine, Vol. 25, p. 882-896 (2019). doi:10.1016/j.molmed.2019.04.009.

http://hdl.handle.net/2078.1/217090

Al Houayek, Mireille ; Rankin, Linda ; Gouveia-Figueira, Sandra ; Fowler, Christopher J. Interferon γ treatment increases endocannabinoid and related N -acylethanolamine levels in T84 human colon carcinoma cells : NAEs in IFNγ-treated T84 cells. In: British Journal of Pharmacology, Vol. 176, p. 1470-1480 (2019). doi:10.1111/bph.14135 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/210202

Szeremeta, Janis ; Karlsson, Jessica ; Al Houayek, Mireille ; Fowler, Christopher J.. Low mRNA expression and activity of monoacylglycerol lipase in human SH-SY5Y neuroblastoma cells. In: Prostaglandins & Other Lipid Mediators, Vol. 142, p. 59-67 (2019). doi:10.1016/j.prostaglandins.2019.04.003 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/225646

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Muccioli, Giulio ; Al Houayek, Mireille. Prostaglandin D2-glycerol ester decreases carrageenan-induced inflammation and hyperalgesia in mice. In: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, Vol. 1864, p. 609-619 (2019).

http://hdl.handle.net/2078.1/211917

Al Houayek, Mireille ; Sorti, René ; Gilthorpe, Jonathan D. ; Fowler, Christopher J.. Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells. In: Scientific Reports, Vol. 9, no. 1 (2019) (2019). doi:10.1038/s41598-019-44057-x (Accepté/Sous presse).

http://hdl.handle.net/2078.1/225645

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Al Houayek, Mireille ; Muccioli, Giulio. The α/β–hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids. In: The FASEB Journal, Vol. 33, no. 6, p. 7635-7646 (2019). doi:10.1096/fj.201802259r.

http://hdl.handle.net/2078.1/217091

Cheng, Ran ; Mori, Wakana ; Ma, Longle ; Al Houayek, Mireille ; Hatori, Akiko ; Zhang, Yiding ; Ogasawara, Daisuke ; Yuan, Gengyang ; Chen, Zhen ; Zhang, Xiaofei ; Shi, Hang ; Yamasaki, Tomoteru ; Xie, Lin ; Kumata, Katsushi ; Fujinaga, Masayuki ; Nagai, Yuji ; Minamimoto, Takafumi ; Svensson, Mona ; Wang, Lu ; Du, Yunfei ; Ondrechen, Mary Jo ; Vasdev, Neil ; Cravatt, Benjamin F. ; Fowler, Christopher ; Zhang, Ming-Rong ; Liang, Steven H.. In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies. In: Journal of Medicinal Chemistry, Vol. 61, no.6, p. 2278-2291 (2018). doi:10.1021/acs.jmedchem.7b01400 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/210200

Al Houayek, Mireille ; Gouveia-Figueira, Sandra ; Hammarström, Marie-Louise ; Fowler, Christopher J. Involvement of CYP1B1 in interferon γ-induced alterations of epithelial barrier integrity.. In: British Journal of Pharmacology, Vol. 175, no.6, p. 877-890 (2018). doi:10.1111/bph.14122.

http://hdl.handle.net/2078.1/196210

Masquelier, Julien ; Al Houayek, Mireille ; Terrasi, Romano ; Bottemanne, Pauline ; Paquot, Adrien ; Muccioli, Giulio. Lysophosphatidylinositols in inflammation and macrophage activation: Altered levels and anti-inflammatory effects.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1863, no.12, p. 1458-1468 (2018). doi:10.1016/j.bbalip.2018.09.003.

http://hdl.handle.net/2078.1/204354

Al Houayek, Mireille ; Masquelier, Julien ; Muccioli, Giulio. Lysophosphatidylinositols, from Cell Membrane Constituents to GPR55 Ligands. In: Trends in Pharmacological Sciences, Vol. 39, no.6, p. 586-604 (2018). doi:10.1016/j.tips.2018.02.011.

http://hdl.handle.net/2078.1/199630

Bottemanne, Pauline ; Muccioli, Giulio ; Al Houayek, Mireille. N -acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities. In: Drug Discovery Today, Vol. 23, no. 8, p. 1520-1529 (2018). doi:10.1016/j.drudis.2018.03.007.

http://hdl.handle.net/2078.1/199632

Mutemberezi, Valentin ; Buisseret, Baptiste ; Masquelier, Julien ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio. Oxysterol levels and metabolism in the course of neuroinflammation: insights from in vitro and in vivo models. In: Journal of Neuroinflammation, Vol. 15, no.1, p. 1-10 (2018). doi:10.1186/s12974-018-1114-8.

http://hdl.handle.net/2078.1/199633

Guillemot-Legris, Owein ; Buisseret, Baptiste ; Mutemberezi, Valentin ; Hermans, Emmanuel ; Deumens, Ronald ; Al Houayek, Mireille ; Muccioli, Giulio. Post-operative pain in mice is prolonged by diet-induced obesity and rescued by dietary intervention.. In: Brain, Behavior, and Immunity, (2018). doi:10.1016/j.bbi.2018.07.022.

http://hdl.handle.net/2078.1/204362

Xu, Yining ; Carradori, Dario ; Al Houayek, Mireille ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique ; Beloqui Garcia, Ana. Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.. In: Molecular pharmaceutics, Vol. 15, no. 1, p. 108-115 (2018). doi:10.1021/acs.molpharmaceut.7b00742.

http://hdl.handle.net/2078.1/204371

De Berdt, Pauline ; Bottemanne, Pauline ; Bianco, John ; Al Houayek, Mireille ; Diogenes, Anibal ; Llyod, Amy ; Gerardo-Nava, Jose ; Brook, Gary A. ; Miron, Véronique ; Muccioli, Giulio ; des Rieux, Anne. Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion. In: Cellular and Molecular Life Sciences, Vol. 75, p. 2843-2856 (2018). doi:10.1007/s00018-018-2764-5.

http://hdl.handle.net/2078.1/199631

Al Houayek, Mireille ; Buisseret, Baptiste ; Paquot, Adrien ; Guillemot-Legris, Owein ; Muccioli, Giulio. The endogenous bioactive lipid prostaglandin D2-glycerol ester reduces murine colitis via DP1 and PPARγ receptors. In: The FASEB Journal, , p. fj.201701205R (2018). doi:10.1096/fj.201701205r (Accepté/Sous presse).

http://hdl.handle.net/2078.1/199628

Karlsson, Jessica ; Gouveia-Figueira, Sandra ; Al Houayek, Mireille ; Fowler, Christopher J.. Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. In: PLOS ONE, Vol. 12, no.9, p. e0185011 (2017). doi:10.1371/journal.pone.0185011.

http://hdl.handle.net/2078.2/210204

Newson, Justine ; Motwani, Madhur P. ; Kendall, Alexandra C. ; Nicolaou, Anna ; Muccioli, Giulio ; Al Houayek, Mireille ; Bennett, Melanie ; Van De Merwe, Rachel ; James, Sarah ; De Maeyer, Roel P.H. ; Gilroy, Derek W.. Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E 2. In: Cell Reports, Vol. 20, no. 13, p. 3162-3175 (2017). doi:10.1016/j.celrep.2017.08.098.

http://hdl.handle.net/2078.1/193464

Al Houayek, Mireille ; Bottemanne, Pauline ; Makriyannis, Alexandros ; Muccioli, Giulio. N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation. In: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, Vol. 1862, no. 5, p. 474-484 (2017). doi:10.1016/j.bbalip.2017.01.001.

http://hdl.handle.net/2078.1/181908

Hashemian, Sanaz ; Al Houayek, Mireille ; Fowler, Christopher J. TLR4 receptor expression and function in F11 dorsal root ganglion × neuroblastoma hybrid cells. In: Innate Immunity, Vol. 23, no.8, p. 687-696 (2017). doi:10.1177/1753425917732824.

http://hdl.handle.net/2078.1/210203

Gabrielsson, Linda ; Gouveia-Figueira, Sandra ; Häggström, Jenny ; Al Houayek, Mireille ; Fowler, Christopher J.. The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line. In: Pharmacology Research & Perspectives, Vol. 5, no. 2, p. e00300 (2017). doi:10.1002/prp2.300.

http://hdl.handle.net/2078.1/210205

Gabrielsson, Linda ; Gouveia-Figueira, Sandra ; Häggström, Jenny ; Al Houayek, Mireille ; Fowler, Christopher J. The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line.. In: Pharmacology research & perspectives, Vol. 5, no.2, p. e00300 (2017). doi:10.1002/prp2.300 (Soumis).

http://hdl.handle.net/2078.1/225752

Beloqui Garcia, Ana ; Al Houayek, Mireille ; Carradori, Dario ; Vanvarenberg, Kevin ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique. A Mechanistic Study on Nanoparticle-Mediated Glucagon-Like Peptide-1 (GLP-1) Secretion from Enteroendocrine L Cells.. In: Molecular Pharmaceutics, Vol. 13, no.12, p. 4222-4230 (2016). doi:10.1021/acs.molpharmaceut.6b00871.

http://hdl.handle.net/2078.1/178983

Beloqui Garcia, Ana ; Memvanga Bondo, Patrick ; Coco, Régis ; Reimondez-Troitiño, Sonia ; Al Houayek, Mireille ; Muccioli, Giulio ; Alonso, María José ; Csaba, Noemi ; de la Fuente, María ; Préat, Véronique. A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease.. In: Colloids and Surfaces B: Biointerfaces, Vol. 143, p. 327-335 (2016). doi:10.1016/j.colsurfb.2016.03.038.

http://hdl.handle.net/2078.1/174760

Guada ramirez, Melissa ; Beloqui Garcia, Ana ; Al Houayek, Mireille ; Muccioli, Giulio ; Dios-Viéitez, Maria del Carmen ; Préat, Véronique ; Blanco-Prieto, Maria J.. Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease. In: International Journal of Pharmaceutics, Vol. 503, no. 1-2, p. 196-198 (2016). doi:10.1016/j.ijpharm.2016.03.012.

http://hdl.handle.net/2078.1/175320

Guillemot-Legris, Owein ; Masquelier, Julien ; Everard, Amandine ; Cani, Patrice D. ; Al Houayek, Mireille ; Muccioli, Giulio. High-fat diet feeding differentially affects the development of inflammation in the central nervous system. In: Journal of Neuroinflammation, Vol. 13, no.1, p. 206 [1-11] (2016). doi:10.1186/s12974-016-0666-8.

http://hdl.handle.net/2078.1/180713

Orefice, Nicola S. ; Al Houayek, Mireille ; Carotenuto, Antonio ; Montella, Silvana ; Barbato, Franscesco ; Comelli, Albert ; Calignano, Antonio ; Muccioli, Giulio ; Orefice, Giuseppe. Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis. In: Neurotherapeutics, Vol. 13, no. 2, p. 428-438 (2016). doi:10.1007/s13311-016-0420-z.

http://hdl.handle.net/2078.1/175321

Geurts, Lucie ; Everard, Amandine ; Van Hul, Matthias ; Essaghir, Ahmed ; Duparc, Thibaut ; Matamoros, Sébastien ; Plovier, Hubert ; Castel, Julien ; Denis, Raphael G P ; Bergiers, Marie ; Druart, Céline ; Al Houayek, Mireille ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Demoulin, Jean-Baptiste ; Luquet, Serge ; Cani, Patrice D.. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. In: Nature Communications, Vol. 6, p. 6495 [1-15] (2015). doi:10.1038/ncomms7495.

http://hdl.handle.net/2078.1/162016

Al Houayek, Mireille ; Bottemanne, Pauline ; Subramanian, Kumar V ; Lambert, Didier ; Makriyannis, Alexandros ; Cani, Patrice D. ; Muccioli, Giulio. N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis. In: The FASEB Journal, Vol. 29, no.2, p. 650-661 (2015). doi:10.1096/fj.14-255208.

http://hdl.handle.net/2078.1/157086

Al Houayek, Mireille ; Muccioli, Giulio. COX-2-derived endocannabinoid metabolites as novel inflammatory mediators. In: Trends in Pharmacological Sciences, Vol. 35, no.6, p. 284-292 (2014). doi:10.1016/j.tips.2014.03.001.

http://hdl.handle.net/2078.1/145133

Al Houayek, Mireille ; Masquelier, Julien ; Muccioli, Giulio. Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy. In: Drug Discovery Today, Vol. 19, no. 3, p. 295-304 (2014). doi:10.1016/j.drudis.2013.07.009.

http://hdl.handle.net/2078.1/141045

Al Houayek, Mireille ; Muccioli, Giulio. Harnessing the anti-inflammatory potential of palmitoylethanolamide.. In: Drug discovery today, , no.1-8 (2014). doi:10.1016/j.drudis.2014.06.007 (Accepté/Sous presse).

http://hdl.handle.net/2078.1/145135

Beloqui Garcia, Ana ; Coco, Régis ; Al Houayek, Mireille ; Solinís, María Ángeles ; Rodríguez-Gascón, Alicia ; Muccioli, Giulio ; Préat, Véronique. Budesonide-loaded nanostructured lipid carriers reduce inflammation in murine DSS-induced colitis. In: International Journal of Pharmaceutics, Vol. 454, no. 2, p. 775-783 (2013). doi:10.1016/j.ijpharm.2013.05.017.

http://hdl.handle.net/2078.1/131923

Al Houayek, Mireille ; Masquelier, Julien ; Cani, Patrice D. ; Lambert, Didier M. ; Muccioli, Giulio. Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. In: Proceedings of the National academy of sciences of the United States of America, Vol. 110, no.43, p. 17558-17563 (2013). doi:10.1073/pnas.1314017110.

http://hdl.handle.net/2078.1/134706

Al Houayek, Mireille ; Muccioli, Giulio. The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. In: Trends in Molecular Medicine, Vol. 18, no. 10, p. 615-625 (2012). doi:10.1016/j.molmed.2012.07.009.

http://hdl.handle.net/2078.1/141217

Al Houayek, Mireille ; Muccioli, Giulio. Pharmacological Aspects of Anandamide and 2-Arachidonoyglycerol as Bioactive Lipids. In: Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment, Elsevier, 2017, 616–629. 978-012800827-0;978-012800756-3. doi:10.1016/B978-0-12-800756-3.00074-0.

http://hdl.handle.net/2078.1/185914