Prof. Antonio MACCHIARULO
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Italy

Untangling the Complexity of a Moonlight Enzyme: A Biophysical Deep Dive into IDO1

Related publications:
•    Jeffery CJ. Moonlighting proteins. Trends Biochem. Sci. 1999. doi: 10.1016/s0968-0004(98)01335-8 
•    Pallotta MT, et al. Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme. FEBS J. 2022. doi: 10.1111/febs.16086 
•    Coletti A. Ligand-induced conformations and dynamic allosteric motions of IDO1 affecting the recruitment of a protein signaling partner. Commun Chem. 2025. doi: 10.1038/s42004-025-01648-2

Info: raphael.frederick@uclouvain.be