Publications

Moens de Hase, Emilie ; Petitfils, Camille ; Al Houayek, Mireille ; Depommier, Clara ; Le Faouder, Pauline ; Delzenne, Nathalie M. ; Van Hul, Matthias ; Muccioli, Giulio ; Cenac, Nicolas ; Cani, Patrice D..

Dysosmobacter welbionis effects on glucose, lipid, and energy metabolism are associated with specific bioactive lipids. In: Journal of lipid research, Vol. 64, no. 10, p. 100437 [1-14] (2023). doi:10.1016/j.jlr.2023.100437.

Roumain, Martin ; Guillemot-Legris, Owein ; Ameraoui, Hafsa ; Al Houayek, Mireille ; Muccioli, Giulio.

Identification and in vivo detection of side-chain hydroxylated metabolites of 4β-hydroxycholesterol. In: The Journal of Steroid Biochemistry and Molecular Biology, Vol. 234, p. 106376 (2023). doi:10.1016/j.jsbmb.2023.106376.

Mwema, Ariane ; Bottemanne, Pauline ; Paquot, Adrien ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Al Houayek, Mireille ; Muccioli, Giulio ; des Rieux, Anne.

Lipid nanocapsules for the nose-to-brain delivery of the anti-inflammatory bioactive lipid PGD-G.. In: Nanomedicine : nanotechnology, biology, and medicine, Vol. 48, p. 102633 (2023). doi:10.1016/j.nano.2022.102633.

Abdul Khaliq, Hafiz ; Al Houayek, Mireille ; Quetin-Leclercq, Joëlle ; Muccioli, Giulio.

5'AMP-activated protein kinase: an emerging target of phytochemicals to treat chronic inflammatory diseases.. In: Critical reviews in food science and nutrition, , p. [1-26] (2022). doi:10.1080/10408398.2022.2145264 (Accepté/Sous presse).

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle.

Dereplication and Quantification of Major Compounds of L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages.. In: Molecules (Basel, Switzerland), Vol. 27, no.3, p. 963 [1-19] (2022). doi:10.3390/molecules27030963.

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Neyts, Tanguy ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle.

Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents. In: Toxicology Reports, Vol. 9, p. 1742-1753 (2022). doi:10.1016/j.toxrep.2022.09.004.

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio.

25-Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice.. In: FASEB journal, Vol. 35, no.4, p. e21514 [1-19] (2021). doi:10.1096/fj.202002555R.

Al Houayek, Mireille ; Ameraoui, Hafsa ; Muccioli, Giulio.

Bioactive lipids in inflammatory bowel diseases - From pathophysiological alterations to therapeutic opportunities.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1866, no.2, p. 158854 [1-18] (2021). doi:10.1016/j.bbalip.2020.158854.

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Ben Kouidar, Youssef ; Paquot, Adrien ; Muccioli, Giulio ; Al Houayek, Mireille.

Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.. In: The FASEB Journal, Vol. 35, no. 4, p. e21411 [1-16] (2021). doi:10.1096/fj.202002468R.

Bottemanne, Pauline ; Guillemot-Legris, Owein ; Paquot, Adrien ; Masquelier, Julien ; Malamas, Michael ; Makriyannis, Alexandros ; Al Houayek, Mireille ; Muccioli, Giulio.

N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.. In: Neurotherapeutics, , p. [1-19] (2021). doi:10.1007/s13311-021-01074-x (Accepté/Sous presse).

Al Houayek, Mireille ; Bannenberg, Gerard ; Muccioli, Giulio ; Norel, Xavier ; Yao, Chengcan ; Schebb, Nils Helge.

Editorial-Special issue of the 7 European workshop on lipid mediators.. In: Prostaglandins & other lipid mediators, Vol. 148, p. 106421 [1-3] (2020). doi:10.1016/j.prostaglandins.2020.106421.

Al Houayek, Mireille ; Stafberg, Linda ; Karlsson, Jessica ; Bergström, Sofia Halin ; Fowler, Christopher J.

Effects of orthotopic implantation of rat prostate tumour cells upon components of the N-acylethanolamine and monoacylglycerol signalling systems: an mRNA study.. In: Scientific reports, Vol. 10, no. 1, p. 6314 (2020). doi:10.1038/s41598-020-63198-y.

Orefice, Nicola S ; Guillemot-Legris, Owein ; Capasso, Rosanna ; Bottemanne, Pauline ; Hantraye, Philippe ; Caraglia, Michele ; Orefice, Giuseppe ; Al Houayek, Mireille ; Muccioli, Giulio.

miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions.. In: eLife, Vol. 9, p. e56916 [1-25] (2020). doi:10.7554/eLife.56916.

Gillard, Justine ; Roumain, Martin ; Picalausa, Corinne ; Thibaut, Morgane ; Clerbaux, Laure-Alix ; Tailleux, Anne ; Staels, Bart ; Muccioli, Giulio ; Bindels, Laure B. ; Leclercq, Isabelle.

A gut microbiota-independent mechanism shapes the bile acid pool in mice with MASH. In: JHEP Reports, Vol. 6, no. 11, p. 101148 [1-11] (2024). doi:10.1016/j.jhepr.2024.101148 (Accepté/Sous presse).

Marotti, Valentina ; Xu, Yiqing ; Bohns Michalowski, Cecilia ; Zhang, Wunan ; Ladeiro Domingues, Inês ; Ameraoui, Hafsa ; Moreels, Tom ; Baatsen, Pieter ; Van Hul, Matthias ; Muccioli, Giulio ; Cani, Patrice D. ; Al Houayek, Mireille ; Malfanti, Alessio ; Beloqui Garcia, Ana.

A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment. In: Bioactive Materials, Vol. 32, p. 206-221 (2024). doi:10.1016/j.bioactmat.2023.09.014.

Muccioli, Giulio ; Bannenberg, Gerard.

Editorial – Special issue of the 8th European Workshop on Lipid Mediators. In: Prostaglandins & Other Lipid Mediators, Vol. 172, no., p. 106835 (2024). doi:10.1016/j.prostaglandins.2024.106835.

Paone, Paola ; Latousakis, Dimitris ; Terrasi, Romano ; Vertommen, Didier ; Jian, Ching ; Borlandelli, Valentina ; Suriano, Francesco ; Johansson, Malin E V ; Puel, Anthony ; Bouzin, Caroline ; Delzenne, Nathalie M. ; Salonen, Anne ; Juge, Nathalie ; Florea, Bogdan I ; Muccioli, Giulio ; Overkleeft, Herman ; Van Hul, Matthias ; Cani, Patrice D..

Human milk oligosaccharide 2'-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and faecal proteome profiles in mice.. In: Gut, Vol. X, no.1, p. 18 (2024). doi:10.1136/gutjnl-2023-330301.

Mwema, Ariane ; Gratpain, Viridiane ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Perdaens, Océane ; Van Pesch, Vincent ; Muccioli, Giulio ; des Rieux, Anne.

Impact of calcitriol and PGD2-G-loaded lipid nanocapsules on oligodendrocyte progenitor cell differentiation and remyelination. In: Drug Delivery and Translational Research, (2024). doi:10.1007/s13346-024-01535-8.

Gratpain, Viridiane ; Loriot, Axelle ; Bottemanne, Pauline ; d'Auria, Ludovic ; Terrasi, Romano ; Payen, Valéry L ; Van Pesch, Vincent ; Muccioli, Giulio ; des Rieux, Anne.

Influence of a pro-inflammatory stimulus on the miRNA and lipid content of human dental stem cell-derived extracellular vesicles and their impact on microglial activation.. In: Heliyon, Vol. 10, no.5, p. e27025 (2024). doi:10.1016/j.heliyon.2024.e27025.

Labrak, Y ; Al Houayek, Mireille ; Mwema, Ariane ; d'Auria, L ; Ucakar, Bernard ; Van Pesch, Vincent ; Muccioli, Giulio ; des Rieux, Anne.

The combined administration of LNC-encapsulated retinoic acid and calcitriol stimulates oligodendrocyte progenitor cell differentiation in vitro and in vivo after intranasal administration.. In: International journal of pharmaceutics, Vol. 659, p. 124237 (2024). doi:10.1016/j.ijpharm.2024.124237 (Accepté/Sous presse).

Romano, Adele ; Friuli, Marzia ; Eramo, Barbara ; Gallelli, Cristina Anna ; Koczwara, Justyna Barbara ; Azari, Elnaz Karimian ; Paquot, Adrien ; Arnold, Myrtha ; Langhans, Wolfgang ; Muccioli, Giulio ; Lutz, Thomas Alexander ; Gaetani, Silvana.

"To brain or not to brain": evaluating the possible direct effects of the satiety factor oleoylethanolamide in the central nervous system.. In: Frontiers in endocrinology, Vol. 14, p. 1158287 [1-12] (2023). doi:10.3389/fendo.2023.1158287.

van Dijk, Myrthe J ; van Oirschot, Brigitte A ; Harrison, Alexander N ; Recktenwald, Steffen M ; Qiao, Min ; Stommen, Amaury ; Cloos, Anne-Sophie ; Vanderroost, Juliette ; Terrasi, Romano ; Dey, Kuntal ; Bos, Jennifer ; Rab, Minke A E ; Bogdanova, Anna ; Minetti, Giampaolo ; Muccioli, Giulio ; Tyteca, Donatienne ; Egée, Stéphane ; Kaestner, Lars ; Molday, Robert S ; van Beers, Eduard J ; van Wijk, Richard.

A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia.. In: American journal of hematology, Vol. 98, no. 12, p. 1877-1887 (2023). doi:10.1002/ajh.27088.

Moens de Hase, Emilie ; Petitfils, Camille ; Al Houayek, Mireille ; Depommier, Clara ; Le Faouder, Pauline ; Delzenne, Nathalie M. ; Van Hul, Matthias ; Muccioli, Giulio ; Cenac, Nicolas ; Cani, Patrice D..

Dysosmobacter welbionis effects on glucose, lipid, and energy metabolism are associated with specific bioactive lipids. In: Journal of lipid research, Vol. 64, no. 10, p. 100437 [1-14] (2023). doi:10.1016/j.jlr.2023.100437.

Ruiz, Florian ; Peter, Benjamin ; Rebeaud, Jessica ; Vigne, Solenne ; Bressoud, Valentine ; Roumain, Martin ; Wyss, Tania ; Yersin, Yannick ; Wagner, Ingrid ; Kreutzfeldt, Mario ; Pimentel Mendes, Marisa ; Kowalski, Camille ; Boivin, Gael ; Roth, Leonard ; Schwaninger, Markus ; Merkler, Doron ; Muccioli, Giulio ; Hugues, Stephanie ; Petrova, Tatiana V ; Pot, Caroline.

Endothelial cell-derived oxysterol ablation attenuates experimental autoimmune encephalomyelitis.. In: EMBO reports, Vol. 24, no.3, p. e55328 [1-20] (2023). doi:10.15252/embr.202255328.

Hoste, Emilia ; Paquot, Adrien ; Panin, Nadtha ; Horion, Shaleena ; El-Hamdaoui, Halima ; Muccioli, Giulio ; Haufroid, Vincent ; Elens, Laure.

Genetic polymorphisms in SLCO2B1 and ABCC1 conjointly modulate atorvastatin intracellular accumulation in HEK293 recombinant cell lines. In: Therapeutic drug monitoring, Vol. 45, no. 3, p. 400-408 (2023). doi:10.21203/rs.3.rs-1520877/v1.

Roumain, Martin ; Guillemot-Legris, Owein ; Ameraoui, Hafsa ; Al Houayek, Mireille ; Muccioli, Giulio.

Identification and in vivo detection of side-chain hydroxylated metabolites of 4β-hydroxycholesterol. In: The Journal of Steroid Biochemistry and Molecular Biology, Vol. 234, p. 106376 (2023). doi:10.1016/j.jsbmb.2023.106376.

Mwema, Ariane ; Muccioli, Giulio ; des Rieux, Anne.

Innovative drug delivery strategies to the CNS for the treatment of multiple sclerosis.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 364, p. 435-457 (2023). doi:10.1016/j.jconrel.2023.10.052.

Régnier, Marion ; Van Hul, Matthias ; Roumain, Martin ; Paquot, Adrien ; de Wouters d’Oplinter, Alice ; Suriano, Francesco ; Everard, Amandine ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Cani, Patrice D..

Inulin increases the beneficial effects of rhubarb supplementation on high-fat high-sugar diet-induced metabolic disorders in mice: impact on energy expenditure, brown adipose tissue activity, and microbiota. In: Gut microbes, Vol. 15, no. 1, p. 20 [1-19] (2023). doi:10.1080/19490976.2023.2178796.

Mwema, Ariane ; Bottemanne, Pauline ; Paquot, Adrien ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Al Houayek, Mireille ; Muccioli, Giulio ; des Rieux, Anne.

Lipid nanocapsules for the nose-to-brain delivery of the anti-inflammatory bioactive lipid PGD-G.. In: Nanomedicine : nanotechnology, biology, and medicine, Vol. 48, p. 102633 (2023). doi:10.1016/j.nano.2022.102633.

Karemera, Manon ; Verce, Marko ; Roumain, Martin ; Muccioli, Giulio ; Cani, Patrice D. ; Everard, Amandine ; Stéphenne, Xavier ; Sokal, Etienne.

Pediatric Autoimmune or Primary Sclerosing Cholangitis: Metronidazole Effectiveness on Biochemical Data, Bile Acid Profile, and Gut Microbiota: A Pilot Study. In: JPGN reports, Vol. 4, no. 3, p. e334 [1-8] (2023). doi:10.1097/pg9.0000000000000334.

Cloos, Anne-Sophie ; Rab, Minke AE ; Van Der Smissen, Patrick ; van Oirschot, Brigitte A ; Mignolet, Eric ; van der Net, Jeroen B ; Koster, Ad ; Kleinen, Kelly ; Larondelle, Yvan ; Terrasi, Romano ; Muccioli, Giulio ; van Wijk, Richard ; Tyteca, Donatienne.

Red blood cells from patients with sitosterolemia exhibit impaired membrane lipid composition and distribution and decreased deformability. In: Frontiers in Hematology. Red Cells, Iron and Erythropoiesis, Vol. 2, p. 055086 [1-14] (2023). doi:10.3389/frhem.2023.1055086.

van Doorslaer de ten Ryen, Sophie ; Dalle, Sebastiaan ; Terrasi, Romano ; Koppo, Katrien ; Muccioli, Giulio ; Deldicque, Louise.

Regulation of the endocannabinoid system by endurance and resistance exercise in hypoxia in human skeletal muscle.. In: Journal of applied physiology, Vol. 134, no. 3, p. 569-580 (2023). doi:10.1152/japplphysiol.00645.2022.

Paquot, Adrien ; Bestard-Escalas, Juan ; Muccioli, Giulio.

Set up and validation of a sensitive method to quantify prostaglandins, prostaglandin-glycerol esters and prostaglandin-ethanolamides, as well as their respective precursors.. In: Prostaglandins & other lipid mediators, , p. 106763 (2023). doi:10.1016/j.prostaglandins.2023.106763 (Accepté/Sous presse).

Abdul Khaliq, Hafiz ; Al Houayek, Mireille ; Quetin-Leclercq, Joëlle ; Muccioli, Giulio.

5'AMP-activated protein kinase: an emerging target of phytochemicals to treat chronic inflammatory diseases.. In: Critical reviews in food science and nutrition, , p. [1-26] (2022). doi:10.1080/10408398.2022.2145264 (Accepté/Sous presse).

Ranaivo, Harimalala ; Zhang, Zhengxiao ; Alligier, Maud ; Van Den Berghe, Laurie ; Sothier, Monique ; Lambert-Porcheron, Stéphanie ; Feugier, Nathalie ; Cuerq, Charlotte ; Machon, Christelle ; Neyrinck, Audrey M. ; Seethaler, Benjamin ; Rodriguez, Julie ; Roumain, Martin ; Muccioli, Giulio ; Maquet, Véronique ; Laville, Martine ; Bischoff, Stephan C ; Walter, Jens ; Delzenne, Nathalie M. ; Nazare, Julie-Anne.

Chitin-glucan supplementation improved postprandial metabolism and altered gut microbiota in subjects at cardiometabolic risk in a randomized trial.. In: Scientific reports, Vol. 12, no.1, p. 8830 [1-14] (2022). doi:10.1038/s41598-022-12920-z.

Mozaheb, Negar ; Van Der Smissen, Patrick ; Opsomer, Tomas ; Mignolet, Eric ; Terrasi, Romano ; Paquot, Adrien ; Larondelle, Yvan ; Dehaen, Wim ; Muccioli, Giulio ; Mingeot-Leclercq, Marie-Paule.

Contribution of Membrane Vesicle to Reprogramming of Bacterial Membrane Fluidity in Pseudomonas aeruginosa.. In: mSphere, Vol. 7, no. 3, p. e0018722 [1-13] (2022). doi:10.1128/msphere.00187-22.

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle.

Dereplication and Quantification of Major Compounds of L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages.. In: Molecules (Basel, Switzerland), Vol. 27, no.3, p. 963 [1-19] (2022). doi:10.3390/molecules27030963.

Bozzato, Elia ; Tsakiris, Nikolaos ; Paquot, Adrien ; Muccioli, Giulio ; Bastiancich, Chiara ; Préat, Véronique.

Dual-drug loaded nanomedicine hydrogel as a therapeutic platform to target both residual glioblastoma and glioma stem cells.. In: International journal of pharmaceutics, Vol. 628, p. 122341 [1-12] (2022). doi:10.1016/j.ijpharm.2022.122341.

Le Roy, Tiphaine ; Moens De Hase, Emilie ; Van Hul, Matthias ; Paquot, Adrien ; Pelicaen, Rudy ; Régnier, Marion ; Depommier, Clara ; Druart, Céline ; Everard, Amandine ; Maiter, Dominique ; Delzenne, Nathalie M. ; Bindels, Laure B. ; de Barsy, Marie ; Loumaye, Audrey ; Hermans, Michel ; Thissen, Jean-Paul ; Vieira-Silva, Sara ; Falony, Gwen ; Raes, Jeroen ; Muccioli, Giulio ; Cani, Patrice D..

Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice. In: Gut, Vol. 71, p. 534–543 (2022). doi:10.1136/gutjnl-2020-323778.

Copperi, Francesca ; Schleis, Inna ; Roumain, Martin ; Muccioli, Giulio ; Casola, Stefano ; Klingenspor, Martin ; Pfeifer, Alexander ; Gnad, Thorsten.

EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes.. In: Communications biology, Vol. 5, no.1, p. 280 [1-9] (2022). doi:10.1038/s42003-022-03201-6.

Abdul Khaliq, Hafiz ; Ortiz Aguirre, Sergio Enrique ; Al Houayek, Mireille ; Neyts, Tanguy ; Muccioli, Giulio ; Quetin-Leclercq, Joëlle.

Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents. In: Toxicology Reports, Vol. 9, p. 1742-1753 (2022). doi:10.1016/j.toxrep.2022.09.004.

Barington, Line ; Christensen, Liv von Voss ; Pedersen, Kristian Kåber ; Niss Arfelt, Kristine ; Roumain, Martin ; Jensen, Kristian Høj Reveles ; Kjær, Viktoria Madeline Skovgaard ; Daugvilaite, Viktorija ; Kearney, John F ; Christensen, Jan Pravsgaard ; Hjortø, Gertrud Malene ; Muccioli, Giulio ; Holst, Peter Johannes ; Rosenkilde, Mette Marie.

GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity.. In: Cells, Vol. 11, no.3, p. 494 [1-18] (2022). doi:10.3390/cells11030494.

Berland, Chloé ; Castel, Julien ; Terrasi, Romano ; Montalban, Enrica ; Foppen, Ewout ; Martin, Claire ; Muccioli, Giulio ; Luquet, Serge ; Gangarossa, Giuseppe.

Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis.. In: Molecular psychiatry, Vol. 27, no.4, p. 2340-2354 (2022). doi:10.1038/s41380-021-01428-z.

Labrak, Yasmine ; Heurtault, Béatrice ; Frisch, Benoît ; Saulnier, Patrick ; Lepeltier, Elise ; Miron, Veronique E ; Muccioli, Giulio ; des Rieux, Anne.

Impact of anti-PDGFRα antibody surface functionalization on LNC uptake by oligodendrocyte progenitor cells.. In: International journal of pharmaceutics, Vol. 618, p. 121623 (2022). doi:10.1016/j.ijpharm.2022.121623.

Valderrama, Jaime A. ; Pérez-Herrera, Andrea ; Muccioli, Giulio ; Venegas-Casanova, Edmundo A. ; Jara-Aguilar, Rafael ; Calderon, Pedro Buc ; Benites, Julio ; Mitu, Liviu.

On the Reaction of 2-Alkanoylnaphthohydroquinones with Hydroxylamine: Access to Cytotoxic 2-(Hydroxyamino)-1,4-naphthoquinone and Their 3-(Hydroxyimino)alkyl Analogous. In: Journal of Chemistry, Vol. 2022, p. 1-8 (2022). doi:10.1155/2022/7664037.

De Berdt, Pauline ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Bouzin, Caroline ; Paquot, Adrien ; Gratpain, Viridiane ; Loriot, Axelle ; Payen, Valery ; Bearzatto, Bertrand ; Muccioli, Giulio ; Gatto, Laurent ; Diogenes, A ; des Rieux, Anne.

The human dental apical papilla promotes spinal cord repair through a paracrine mechanism.. In: Cellular and molecular life sciences : CMLS, Vol. 79, no.5, p. 252 (2022). doi:10.1007/s00018-022-04210-8.

Yelek, Caner ; Mignion, Lionel ; Paquot, Adrien ; Bouzin, Caroline ; Corbet, Cyril ; Muccioli, Giulio ; Cani, Patrice D. ; Jordan, Bénédicte.

Tumor Metabolism Is Affected by Obesity in Preclinical Models of Triple-Negative Breast Cancer. In: Cancers, Vol. 14, no. 3, p. 562 [1-16] (2022). doi:10.3390/cancers14030562.

Bottemanne, Pauline ; Paquot, Adrien ; Ameraoui, Hafsa ; Guillemot-Legris, Owein ; Al Houayek, Mireille ; Muccioli, Giulio.

25-Hydroxycholesterol metabolism is altered by lung inflammation, and its local administration modulates lung inflammation in mice.. In: FASEB journal, Vol. 35, no.4, p. e21514 [1-19] (2021). doi:10.1096/fj.202002555R.

Stillemans, Gabriel ; Paquot, Adrien ; Muccioli, Giulio ; Hoste, Emilia ; Panin, Nadtha ; Åsberg, Anders ; Balligand, Jean-Luc ; Haufroid, Vincent ; Elens, Laure.

Atorvastatin population pharmacokinetics in a real‐life setting: Influence of genetic polymorphisms and association with clinical response. In: Clinical and Translational Science, (2021). doi:10.1111/cts.13185.

Thibaut, Morgane ; Gillard, Justine ; Dolly, Adeline ; Roumain, Martin ; Leclercq, Isabelle ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Bindels, Laure B..

Bile Acid Dysregulation Is Intrinsically Related to Cachexia in Tumor-Bearing Mice. In: Cancers, Vol. 13, no.24, p. 6389 [1-17] (2021). doi:10.3390/cancers13246389.

Al Houayek, Mireille ; Ameraoui, Hafsa ; Muccioli, Giulio.

Bioactive lipids in inflammatory bowel diseases - From pathophysiological alterations to therapeutic opportunities.. In: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1866, no.2, p. 158854 [1-18] (2021). doi:10.1016/j.bbalip.2020.158854.

Ange, Marine ; De Poortere, Julien ; Ginion, Audrey ; Battault, Sylvain ; Dechamps, Mélanie ; Muccioli, Giulio ; Roumain, Martin ; Morelle, Johann ; Druart, Sébastien ; Mathivet, Thomas ; Bertrand, Luc ; Castanares Zapatero, Diego ; Horman, Sandrine ; Beauloye, Christophe.

Canagliflozin protects against sepsis capillary leak syndrome by activating endothelial α1AMPK.. In: Scientific reports, Vol. 11, no. 1, p. 13700 [1-13] (2021). doi:10.1038/s41598-021-93156-1.

Van Den Brûle, Sybille ; Rappe, Margaux ; Ambroise, Jérôme ; Bouzin, Caroline ; Dessy, Chantal ; Paquot, Adrien ; Muccioli, Giulio ; Lison, Dominique.

Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice.. In: Particle and fibre toxicology, Vol. 18, no. 1, p. 7 [1-15] (2021). doi:10.1186/s12989-021-00400-7.

Perez, Laeticia ; Scarcello, Eleonora ; Ibouraadaten, Saloua ; Yakoub, Yousof ; Leinardi, Riccardo ; Ambroise, Jérôme ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Paquot, Adrien ; Muccioli, Giulio ; Bouzin, Caroline ; Van Den Brûle, Sybille ; Lison, Dominique.

Dietary nanoparticles alter the composition and function of the gut microbiota in mice at dose levels relevant for human exposure.. In: Food and chemical toxicology, Vol. 154, p. 112352 [1-13] (2021). doi:10.1016/j.fct.2021.112352.

Buisseret, Baptiste ; Guillemot-Legris, Owein ; Ben Kouidar, Youssef ; Paquot, Adrien ; Muccioli, Giulio ; Al Houayek, Mireille.

Effects of R-flurbiprofen and the oxygenated metabolites of endocannabinoids in inflammatory pain mice models.. In: The FASEB Journal, Vol. 35, no. 4, p. e21411 [1-16] (2021). doi:10.1096/fj.202002468R.

Gratpain, Viridiane ; Mwema, Ariane ; Labrak, Yasmine ; Muccioli, Giulio ; Van Pesch, Vincent ; des Rieux, Anne.

Extracellular vesicles for the treatment of central nervous system diseasesExtracellular vesicles for the treatment of central nervous system diseases. In: Advanced drug delivery reviews, Vol. 174, p. 535-552 (2021). doi:10.1016/j.addr.2021.05.006.

Genton, Laurence ; Pruijm, Menno ; Teta, Daniel ; Bassi, Isabelle ; Cani, Patrice D. ; Gaïa, Nadia ; Herrmann, François R ; Marangon, Nicola ; Mareschal, Julie ; Muccioli, Giulio ; Stoermann, Catherine ; Suriano, Francesco ; Wurzner-Ghajarzadeh, Arlene ; Lazarevic, Vladimir ; Schrenzel, Jacques.

Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients.. In: Journal of cachexia, sarcopenia and muscle, , p. [1-13] (2021). doi:10.1002/jcsm.12781 (Accepté/Sous presse).

Abot, Anne ; Wemelle, Eve ; Laurens, Claire ; Paquot, Adrien ; Pomie, Nicolas ; Carper, Deborah ; Bessac, Arnaud ; Mas Orea, Xavier ; Fremez, Christophe ; Fontanie, Maxime ; Lucas, Alexandre ; Lesage, Jean ; Everard, Amandine ; Meunier, Etienne ; Dietrich, Gilles ; Muccioli, Giulio ; Moro, Cedric ; Cani, Patrice D. ; Knauf, Claude.

Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice.. In: Gut, Vol. 70, no. 6, p. 1078-1087 (2021). doi:10.1136/gutjnl-2019-320230.

Cloos, Anne-Sophie ; Daenen, Laura G. M. ; Maja, Mauriane ; Stommen, Amaury ; Vanderroost, Juliette ; Van Der Smissen, Patrick ; Rab, Minke ; Westerink, Jan ; Mignolet, Eric ; Larondelle, Yvan ; Terrasi, Romano ; Muccioli, Giulio ; Dumitru, Andra-Cristina ; Alsteens, David ; van Wijk, Richard ; Tyteca, Donatienne.

Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study. In: Frontiers in Physiology, Vol. 12, no. 2, p. 638027 [1-22] (2021). doi:10.3389/fphys.2021.638027.

Thibaut, Morgane ; Sboarina, Martina ; Roumain, Martin ; Pötgens, Sarah ; Neyrinck, Audrey M. ; Destrée, Florence ; Gillard, Justine ; Leclercq, Isabelle ; Dachy, Guillaume ; Demoulin, Jean-Baptiste ; Tailleux, Anne ; Lestavel, Sophie ; Rastelli, Marialetizia ; Everard, Amandine ; Cani, Patrice D. ; Porporato, Paolo E ; Loumaye, Audrey ; Thissen, Jean-Paul ; Muccioli, Giulio ; Delzenne, Nathalie M. ; Bindels, Laure B..

Inflammation-induced cholestasis in cancer cachexia.. In: Journal of cachexia, sarcopenia and muscle, Vol. 12, no. 1, p. 70-20 (2021). doi:10.1002/jcsm.12652.

Bottemanne, Pauline ; Guillemot-Legris, Owein ; Paquot, Adrien ; Masquelier, Julien ; Malamas, Michael ; Makriyannis, Alexandros ; Al Houayek, Mireille ; Muccioli, Giulio.

N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition, but Not Fatty Acid Amide Hydrolase Inhibition, Prevents the Development of Experimental Autoimmune Encephalomyelitis in Mice.. In: Neurotherapeutics, , p. [1-19] (2021). doi:10.1007/s13311-021-01074-x (Accepté/Sous presse).

Suriano, Francesco ; Vieira-Silva, Sara ; Falony, Gwen ; Roumain, Martin ; Paquot, Adrien ; Pelicaen, Rudy ; Régnier, Marion ; Delzenne, Nathalie M. ; Raes, Jeroen ; Muccioli, Giulio ; Van Hul, Matthias ; Cani, Patrice D..

Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin. In: Microbiome, Vol. 9, no.1, p. 147 (2021). doi:10.1186/s40168-021-01097-8.

Neyrinck, Audrey M. ; Rodriguez, Julie (co-first author) ; Zhang, Zhengxiao ; Seethaler, Benjamin ; Robles Sanchez, Candido ; Roumain, Martin ; Hiel, Sophie ; Bindels, Laure B. ; Cani, Patrice D. ; Paquot, Nicolas ; Cnop, Miriam ; Nazare, Julie-Anne ; Laville, Martine ; Muccioli, Giulio ; Bischoff, Stephan C ; Walter, Jens ; Thissen, Jean-Paul ; Delzenne, Nathalie M..

Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial.. In: European journal of nutrition, Vol. 60, no. 6, p. 3159-3170 (2021). doi:10.1007/s00394-021-02484-5 (Accepté/Sous presse).

Buya, Aristote ; Terrasi, Romano ; Mbinze, Jérémie K ; Muccioli, Giulio ; Beloqui Garcia, Ana ; Memvanga, Patrick B ; Préat, Véronique.

Quality-by-Design-Based Development of a Voxelotor Self-Nanoemulsifying Drug-Delivery System with Improved Biopharmaceutical Attributes.. In: Pharmaceutics, Vol. 13, no.9, p. 1388 [1-20] (2021). doi:10.3390/pharmaceutics13091388.

Lison, Dominique ; Ambroise, Jérôme ; Leinardi, Riccardo ; Ibouraadaten, Saloua ; Yakoub, Yousof ; Deumer, Gladys ; Haufroid, Vincent ; Paquot, Adrien ; Muccioli, Giulio ; Van Den Brûle, Sybille.

Systemic effects and impact on the gut microbiota upon subacute oral exposure to silver acetate in rats.. In: Archives of toxicology, Vol. 95, no. 4, p. 1251-1266 (2021). doi:10.1007/s00204-021-02998-1.

Guillemot-Legris, Owein ; Muccioli, Giulio.

The oxysterome and its receptors as pharmacological targets in inflammatory diseases.. In: British journal of pharmacology, (2021). doi:10.1111/bph.15479 (Accepté/Sous presse).

Pollet, Hélène ; Cloos, Anne-Sophie (co-first author) ; Stommen, Amaury ; Vanderroost, Juliette ; Conrard, Louise ; Paquot, Adrien ; Ghodsi, Marine ; Carquin, Mélanie ; Léonard, Anne-Catherine ; Guthmann, Manuel ; Lingurski, Maxime ; Vermylen, Christiane ; Killian, Theodore ; Gatto, Laurent ; Rider, Mark H. ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Vikkula, Miikka ; Brouillard, Pascal ; Van Der Smissen, Patrick ; Muccioli, Giulio ; Tyteca, Donatienne.

Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis. In: Biomolecules, Vol. 10, no. 8, p. 1120 [1-25] (2020). doi:10.3390/biom10081120.

Yelek, Caner ; Mignion, Lionel ; Joudiou, Nicolas ; Terrasi, Romano ; Gourgue, Florian ; Van Hul, Matthias ; Delzenne, Nathalie M. ; Gallez, Bernard ; Corbet, Cyril ; Muccioli, Giulio ; Feron, Olivier ; Cani, Patrice D. ; Jordan, Bénédicte.

Acetate: Friend or foe against breast tumour growth in the context of obesity?. In: Journal of Cellular and Molecular Medicine, Vol. 24, no. 24, p. 14195-14204 (2020). doi:10.1111/jcmm.16034.

Phung, Austin S. ; Bannenberg, Gerard ; Vigor, Claire ; Reversat, Guillaume ; Oger, Camille ; Roumain, Martin ; Galano, Jean-Marie ; Durand, Thierry ; Muccioli, Giulio ; Ismail, Adam ; Wang, Selina C..

Chemical Compositional Changes in Over-Oxidized Fish Oils. In: Foods, Vol. 9, no.10, p. 1501 (2020). doi:10.3390/foods9101501.

Tsakiris, Nikolaos ; Fauvet, Frédérique ; Ruby, Samia ; Puisieux, Alain ; Paquot, Adrien ; Muccioli, Giulio ; Vigneron, Arnaud M ; Préat, Véronique.

Combined nanomedicines targeting colorectal cancer stem cells and cancer cells.. In: Journal of controlled release, Vol. 326, p. 387-395 (2020). doi:10.1016/j.jconrel.2020.07.025.

Le Roy, Tiphaine ; Van Der Smissen, Patrick ; Paquot, Adrien ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Collet, Jean-François ; Cani, Patrice D..

Dysosmobacter welbionis gen. nov., sp. nov., isolated from human faeces and emended description of the genus Oscillibacter.. In: International journal of systematic and evolutionary microbiology, Vol. 70, no. 9, p. 4851-4858 (2020). doi:10.1099/ijsem.0.003547.

Al Houayek, Mireille ; Bannenberg, Gerard ; Muccioli, Giulio ; Norel, Xavier ; Yao, Chengcan ; Schebb, Nils Helge.

Editorial-Special issue of the 7 European workshop on lipid mediators.. In: Prostaglandins & other lipid mediators, Vol. 148, p. 106421 [1-3] (2020). doi:10.1016/j.prostaglandins.2020.106421.

Van Hul, Matthias ; Le Roy, Tiphaine ; Prifti, Edi ; Dao, Maria Carlota ; Paquot, Adrien ; Zucker, Jean-Daniel ; Delzenne, Nathalie M. ; Muccioli, Giulio ; Clément, Karine ; Cani, Patrice D..

From correlation to causality: the case of Subdoligranulum. In: Gut Microbes, Vol. 12, no.1, p. 1-13 (2020). doi:10.1080/19490976.2020.1849998.

Manca, Claudia ; Boubertakh, Besma ; Leblanc, Nadine ; Deschênes, Thomas ; Lacroix, Sebastien ; Martin, Cyril ; Houde, Alain ; Veilleux, Alain ; Flamand, Nicolas ; Muccioli, Giulio ; Raymond, Frédéric ; Cani, Patrice D. ; Di Marzo, Vincenzo ; Silvestri, Cristoforo.

Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling.. In: Journal of lipid research, Vol. 61, no.1, p. 70-85 (2020). doi:10.1194/jlr.RA119000424.

Briand-Mésange, Fabienne ; Pons, Véronique ; Allart, Sophie ; Masquelier, Julien ; Chicanne, Gaëtan ; Beton, Nicolas ; Payrastre, Bernard ; Muccioli, Giulio ; Ausseil, Jérôme ; Davignon, Jean-Luc ; Salles, Jean-Pierre ; Chap, Hugues.

Glycerophosphodiesterase 3 (GDE3) is a lysophosphatidylinositol-specific ectophospholipase C acting as an endocannabinoid signaling switch.. In: The Journal of biological chemistry, Vol. 295, no.46, p. 15767-15781 (2020). doi:10.1074/jbc.RA120.015278.

Lefort, Charlotte ; Roumain, Martin ; Van Hul, Matthias ; Rastelli, Marialetizia ; Manco, Rita ; Leclercq, Isabelle ; Delzenne, Nathalie M. ; Di Marzo, Vincenzo ; Flamand, Nicolas ; Luquet, Serge ; Silvestri, Cristoforo ; Muccioli, Giulio ; Cani, Patrice D..

Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism. In: Cells, Vol. 9, no. 5, p. 1247 [1-23] (2020). doi:10.3390/cells9051247.

Demaret, Tanguy ; Evraerts, Jonathan ; Ravau, Joachim ; Roumain, Martin ; Muccioli, Giulio ; Najimi, Mustapha ; Sokal, Etienne.

High Dose Versus Low Dose Syngeneic Hepatocyte Transplantation in -G844D NMRI Mouse Model is Safe but Does Not Achieve Long Term Engraftment.. In: Cells, Vol. 10, no. 1, p. 40 [1-12] (2020). doi:10.3390/cells10010040.

Valderrama, Jaime A. ; Ríos, David ; Muccioli, Giulio ; Buc Calderon, Pedro ; Benites, Julio.

In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study. In: Molecules, Vol. 25, no.4, p. 953 (2020). doi:10.3390/molecules25040953 (Accepté/Sous presse).

Cloos, Anne-Sophie ; Ghodsi, Marine ; Stommen, Amaury ; Vanderroost, Juliette ; Dauguet, Nicolas ; Pollet, Hélène ; D'Auria, Ludovic ; Mignolet, Eric ; Larondelle, Yvan ; Terrasi, Romano ; Muccioli, Giulio ; Van Der Smissen, Patrick ; Tyteca, Donatienne.

Interplay Between Plasma Membrane Lipid Alteration, Oxidative Stress and Calcium-Based Mechanism for Extracellular Vesicle Biogenesis From Erythrocytes During Blood Storage.. In: Frontiers in Physiology, Vol. 11, p. 712 [1-23] (2020). doi:10.3389/fphys.2020.00712.

Rastelli, Marialetizia ; Van Hul, Matthias ; Terrasi, Romano ; Lefort, Charlotte ; Régnier, Marion ; Beiroa, Daniel ; Delzenne, Nathalie M. ; Everard, Amandine ; Nogueiras, Rubén ; Luquet, Serge ; Muccioli, Giulio ; Cani, Patrice D..

Intestinal NAPE-PLD contributes to short-term regulation of food intake via gut-to-brain axis.. In: American journal of physiology. Endocrinology and metabolism, Vol. 319, no.3, p. E647-E657 (2020). doi:10.1152/ajpendo.00146.2020.

Demaret, Tanguy ; Roumain, Martin ; Ambroise, Jérôme ; Evraerts, Jonathan ; Ravau, Joachim ; Bouzin, Caroline ; Bearzatto, Bertrand ; Gala, Jean-Luc ; Stepman, Hedwig ; Marie, Sandrine ; Vincent, Marie-Françoise ; Muccioli, Giulio ; Najimi, Mustapha ; Sokal, Etienne.

Longitudinal study of Pex1-G844D NMRI mouse model: A robust pre-clinical model for mild Zellweger spectrum disorder. In: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Vol. 1866, no. 11, p. 165900 [1-18] (2020). doi:10.1016/j.bbadis.2020.165900.

Rodriguez, Julie ; Neyrinck, Audrey M. ; Zhang, Zhengxiao ; Seethaler, Benjamin ; Nazare, Julie-Anne ; Robles Sanchez, Candido ; Roumain, Martin ; Muccioli, Giulio ; Bindels, Laure B. ; Cani, Patrice D. ; Maquet, Véronique ; Laville, Martine ; Bischoff, Stephan C ; Walter, Jens ; Delzenne, Nathalie M..

Metabolite profiling reveals the interaction of chitin-glucan with the gut microbiota.. In: Gut microbes, Vol. 12, no. 1, p. 1810530 [1-15] (2020). doi:10.1080/19490976.2020.1810530.

Ríos, David ; Valderrama, Jaime A ; Cautin, Miriam ; Tapia, Milko ; Salas, Felipe ; Guerrero-Castilla, Angélica ; Muccioli, Giulio ; Buc Calderon, Pedro ; Benites, Julio.

New 2-Acetyl-3-aminophenyl-1,4-naphthoquinones: Synthesis and Antiproliferative Activities on Breast and Prostate Human Cancer Cells.. In: Oxidative medicine and cellular longevity, Vol. 2020, p. 8939716 [1-11] (2020). doi:10.1155/2020/8939716.

Diermeier, Theresa ; Meredith, Sean J ; Irrgang, James J ; Zaffagnini, Stefano ; Kuroda, Ryosuke ; Hochino, Yuichi ; Samuelsson, Kristian ; Smith, Clair Nicole ; Popchak, Adam ; Musahl, Volker ; Sheean, Andrew ; Burnham, Jeremy M ; Lian, Jayson ; Smith, Clair ; Popchak, Adam ; Herbst, Elmar ; Pfeiffer, Thomas ; Araujo, Paulo ; Oostdyk, Alicia ; Guenther, Daniel ; Ohashi, Bruno ; Irrgang, James J ; Fu, Freddie H ; Nagamune, Kouki ; Kurosaka, Masahiro ; Kuroda, Ryosuke ; Hochino, Yuichi ; Grassi, Alberto ; Muccioli, Giulio ; Lopomo, Nicola ; Signorelli, Cecilia ; Raggi, Federico ; Zaffagnini, Stefano ; Horvath, Alexandra ; Svantesson, Eleonor ; Senorski, Eric Hamrin ; Sundemo, David ; Bjoernsson, Haukur ; Ahlden, Mattias ; Desai, Neel ; Samuelsson, Kristian ; Karlsson, Jon.

Patient-Reported and Quantitative Outcomes of Anatomic Anterior Cruciate Ligament Reconstruction With Hamstring Tendon Autografts., collab. PIVOT Study Group. In: Orthopaedic journal of sports medicine, Vol. 8, no.7, p. [1-7] (2020). doi:10.1177/2325967120926159 (Accepté/Sous presse).

Orefice, Nicola S ; Guillemot-Legris, Owein ; Capasso, Rosanna ; Bottemanne, Pauline ; Hantraye, Philippe ; Caraglia, Michele ; Orefice, Giuseppe ; Al Houayek, Mireille ; Muccioli, Giulio.

miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions.. In: eLife, Vol. 9, p. e56916 [1-25] (2020). doi:10.7554/eLife.56916.

Morelle, Axel ; Caruano, Joséphine ; Feledziak, Marion ; Michaux, Catherine ; Perpète, Eric ; Muccioli, Giulio ; Marchand-Brynaert, Jacqueline ; Robiette, Raphaël.

β-lactams to act on the endocannabinoid system. In: Chimie Nouvelle, Vol. 134, p. 41 (2020).