Randy BUZISA MBUKU – TFAR FACM/NMSK (IREC)Therapeutic innovation in PJI: A biofilm-disrupting and drug-delivering hydrogel incorporating an enzymatic cocktailPromotor: Prof. Olivier CornuCo-promotor: Prof. Françoise Van BambekeRelated publications :•    Buzisa Mbuku, R, Poilvache H, Maigret L, Vanbever R, Van Bambeke F, Cornu O.

Amandine BASTIN – CMFA/FATHBeyond metabolism: Disrupting PHGDH protein–protein interactions as a therapeutic strategy in colorectal cancerRachel DUBOIS – CMFA Design, synthesis and in vitro pharmacological evaluation of new inhibitors of the CX- system, the cystine/gutamate exchangerDavid NAVARRO SANAGUSTIN – REMA/BPBLImpact of obesity on the metastatic potential of ovarian cancer toward the

Barbara MATHIEU – REMA/FATH (IREC)Deciphering the role of mitochondrial ROS in radiation therapy through their direct detection in vivoPromotor: Prof. Bernard GallezCo-promotor: Prof. Pierre Sonveaux Related publications :•    d’Hose, D.#, Mathieu, B.#, Mignion, L., Hardy, M., Ouari, O., Jordan, BF., Sonveaux, P., & Gallez, B. (2022).

Yasmine BOUIDIDA - IREC-FATH-TUMETABOUnderstanding and targeting tissue-specific metastasis in human pancreatic cancerPromotor: Prof. Pierre SonveauxYasmine VANDENSANDE - REMA and IREC/FATHInduction of a mitochondrial oxidative stress in cholangiocarcinoma to boost the sensitivity to targeted therapyPromotor: Prof. Bernard Gallez, copromotor:  Prof.

Dr Tiffany BELLANGER - Postdoctoral researcherCellular and molecular Pharmacology (TFAR FACM)Characterization of environmental stress resistance in Oenococcus oeni and Staphylococcus aureus via membrane analysis Related publications:Bellanger T, Eicher C, Graces F, Cresson A, Grandvalet C, Alexandre H, Weidmann S (under review, Sci Rep) Impact of N-terminal domain on the s

Giuditta Leone – ADDB/CMFADevelopment of PEG-treprostinil conjugates for sustained local delivery in pulmonary arterial hypertensionPromotor: Prof. Rita VanbeverCo-promotor: Prof. Raphaël FrédérickRelated publications :•    Leone, G., Ucakar, B., Perros, F., Frédérick, R., & Vanbever, R. (2025).

Dr Benjamin ZAGIEL - Postdoctoral researcher - Medicinal Chemistry - CMFATarget-directed Dynamic Combinatorial Chemistry on peptide scaffolds : allowing "undruggable" targets to assemble their own binders for protein-protein interactionsRelated publications:Zagiel Benjamin+, Peker Taleen+, Marquant Rodrigue, Cazals Guillaume, Webb Gabriel, Miclet Emeric, Bich Claudia, Sachon Emmanuelle, Moumné Rob

Prof. Guido BOMMER - de Duve Institute (DDUV/BCHM)Rare metabolites matter: novel players and helpersRelated publications:A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia' Jacobs J, et al in Nature. 2025 Oct;646(8083):218-226.A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis' Wilson et al in Cell.

Thesis public defense of Floriane DEBUISSON – ADDBMesenchymal stem cell spheroids in regenerative medicine, tackling cell survival limitations as a delivery challengePromotor : Prof. Anne des RieuxRelated publications :•    Debuisson F., Ucakar B., Vanvarenberg K., Delongie K-A., Haufroid V., Mwema A., des Rieux A.

Dr Frédéric PERROS  Directeur de Recherches à Lyon University, CarMeN laboratoryTransgenic rat models of Pulmonary Hypertension Related publications:•    Marie Piecyk, Carole Ferraro-Peyret, David Laville, Frederic Perros and Cedric Chaveroux. Novel insights into the GCN2 pathway and its targeting.