NANOBASH
uclouvain |
Human-based methodologies to study toxicity of food nanoparticles on fatty liver diseases via the microbiota-bile acid axis
Every day, people unknowingly consume nanoparticles, tiny particles added to food to preserve it and kill bacteria. What they do to the bacteria in our gut remains largely unknown. Of particular concern is their effect on bile acid metabolism, which influences liver health and could worsen chronic fatty liver disease. The ERC-funded nanoBASH project aims to investigate how food nanoparticles interact with the microbiota–bile acid–liver axis. By combining detailed mechanistic studies with human-relevant testing, the project aims to reveal potential drivers of fatty liver disease and provide tools for precision toxicology and preventive strategies to safeguard health.
This project has received funding from the European Research Council (ERC) under the European Union's Horizon Europe research and innovation programme under the grant agreement number 101221133.