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Greet Kerckhofs
Professeure

SST/EPL Louvain School of Engineering (EPL)

SST/IMMC Institute of Mechanics, Materials and Civil Engineering (iMMC)

SSS/IREC Institut de recherche expérimentale et clinique (IREC)

SST/IMMC/MEED Mechatronic, Electrical Energy, and Dynamic Systems (MEED)

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Hanne, Nicholas J. ; Steward, Andrew J. ; Geeroms, Carla ; Easter, Elizabeth D. ; Gensch, Hannah T. ; Kerckhofs, Greet ; Parac-Vogt, Tatjana N. ; Sheng, Huaxin ; Cole, Jacqueline H.. Ischemic stroke reduces bone perfusion and alters osteovascular structure. In: Bone Reports, Vol. 24, no.-, p. 101824 (2025). doi:10.1016/j.bonr.2025.101824.

Leyssens, Lisa ; El Aazmani, Walid ; Balcaen, Tim ; Jacques, Pascal ; Horman, Sandrine ; Goldman, Jeremy ; Kerckhofs, Greet. MicroCT and contrast-enhanced microCT to study the in vivo degradation behavior and biocompatibility of candidate metallic intravascular stent materials. In: Acta Biomaterialia, Vol. 191, no.-, p. 53-65 (2025). doi:10.1016/j.actbio.2024.11.017.

Morath, Lea ; Rahim, Shebeer A. ; Baker, Cole ; Anderson, Deirdre E.J. ; Hinds, Monica T. ; Sikora-Jasinska, Malgorzata ; Oujiri, Lindy ; Leyssens, Lisa ; Kerckhofs, Greet ; Pyka, Grzegorz ; Oliver, Alexander A. ; Drelich, Jaroslaw W. ; Goldman, Jeremy. The biological effects of copper alloying in Zn-based biodegradable arterial implants. In: Biomaterials Advances, Vol. 167, no.-, p. 214112 (2025). doi:10.1016/j.bioadv.2024.214112.

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Manon, Julie ; Gallant, Laurie ; Gérard, Paul ; Fievé, Lies ; Schneidewind, Pierre ; Pyka, Grzegorz ; Kerckhofs, Greet ; Lengelé, Benoît ; Cornu, Olivier ; Behets Wydemans, Catherine. 2D and 3D microstructural analysis of the iliotibial tract. In: Journal of anatomy, Vol. 245, no. 5, p. 725-739 (2024). doi:10.1111/joa.14125.

Davis, Sarah ; Karali, Aikaterina ; Balcaen, Tim ; Zekonyte, Jurgita ; Pétré, Maïté ; Roldo, Marta ; Kerckhofs, Greet ; Blunn, Gordon. Comparison of two contrast-enhancing staining agents for use in X-ray imaging and digital volume correlation measurements across the cartilage-bone interface. In: Journal of the Mechanical Behavior of Biomedical Materials, Vol. 152, no.-, p. 106414 (2024). doi:10.1016/j.jmbbm.2024.106414.

Lang, Annemarie ; Benn, Andreas ; Collins, Joseph M. ; Wolter, Angelique ; Balcaen, Tim ; Kerckhofs, Greet ; Zwijsen, An ; Boerckel, Joel D.. Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone. In: Communications Biology, Vol. 7, no.1, p. - (2024). doi:10.1038/s42003-024-05915-1.

Balcaen, Tim ; Benova, Andrea ; de Jong, Flip ; de Oliveira Silva, Rodrigo ; Cajka, Tomas ; Sakellariou, Dimitrios ; Tencerova, Michaela ; Kerckhofs, Greet ; De Borggraeve, Wim M.. Exploring contrast-enhancing staining agents for studying adipose tissue through contrast-enhanced computed tomography. In: Journal of Lipid Research, Vol. 65, no.7, p. 100572 (2024). doi:10.1016/j.jlr.2024.100572.

Leyssens, Lisa ; Lapraille, Noémie ; Pyka, Grzegorz ; Jacques, Pascal ; Horman, Sandrine ; Goldman, Jeremy ; Kerckhofs, Greet. Exploring the biodegradability of candidate metallic intravascular stent materials using X-ray microfocus computed tomography: An in vitro study. In: Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 112, no.8, p. e35452 (2024). doi:http://dx.doi.org/10.1002/jbm.b.35452. doi:10.1002/jbm.b.35452.

Muylle, Ewout ; Maes, Arne ; De Hertogh, Gert ; Van De Winkel, Nele ; Kerckhofs, Greet ; Dubois, Antoine ; Vandecaveye, Vincent ; Thorrez, Lieven ; Hennion, Ina ; Emonds, Marie-Paule ; Pans, Steven ; Deferm, Nathalie P. ; Monbaliu, Diethard ; Canovai, Emilio ; Vanuytsel, Tim ; Pirenne, Jacques ; Ceulemans, Laurens J.. Multilevel Analysis of the Neovascularization and Integration Process of a Nonvascularized Rectus Fascia Transplantation. In: Transplantation Direct, Vol. 10, no.6, p. e1624 (2024). doi:10.1097/txd.0000000000001624.

Saraiva Rocha da Silva, Fernando ; Georgiadis, Christos ; Van Droogenbroek, Kevin ; Delmelle, Renaud ; Pinon, Xavier ; Pyka, Grzegorz ; Kerckhofs, Greet ; Egert, Franz ; Razmjooei, Fatemeh ; Ansar, Syed-Asif ; Mitsushima, Shigenori ; Proost, Joris. Proton exchange membrane-like alkaline water electrolysis using flow-engineered three-dimensional electrodes. In: Nature Communications, Vol. 15, p. 7444 (2024).

Docter, Daniël ; Timmerman, Melanie ; Dawood, Yousif ; Hagoort, Jaco ; Lobe, Nick ; van Heurn, Ernst ; Gorter, Ramon ; Jacobs, Karl ; Pyka, Grzegorz ; Kerckhofs, Greet ; van den Hoff, Maurice J.B. ; de Bakker, Bernadette. Scaling up contrast-enhanced micro-CT imaging: Optimizing contrast and acquisition for large ex-vivo human samples. In: Forensic Imaging, Vol. 37, no.-, p. 200596 (2024). doi:10.1016/j.fri.2024.200596.

Pétré, Maïté ; Balcaen, Tim ; Schneidewind, Pierre ; Mazy, Lara ; Pyka, Grzegorz ; Fehervary, Heleen ; Famaey, Nele ; Kerckhofs, Greet. Screening staining agents for contrast-enhanced microCT of vascular tissues: Assessing the effect on microstructural and mechanical properties. In: Tomography of Materials and Structures, Vol. 6, no.100038, p. 100038 (2024). doi:10.1016/j.tmater.2024.100038.

Xie, Meng ; Kaiser, Markéta ; Gershtein, Yaakov ; Schnyder, Daniela ; Deviatiiarov, Ruslan ; Gazizova, Guzel ; Shagimardanova, Elena ; Zikmund, Tomáš ; Kerckhofs, Greet ; Ivashkin, Evgeny ; Batkovskyte, Dominyka ; Newton, Phillip T ; Andersson, Olov ; Fried, Kaj ; Gusev, Oleg ; Zeberg, Hugo ; Kaiser, Jozef ; Adameyko, Igor ; Chagin, Andrei S. The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling. In: Nat Commun, Vol. 15, no.1, p. 2367 (2024). doi:10.1038/s41467-024-46030-3.

Maes, Arne ; Borgel, Onno ; Braconnier, Clara ; Balcaen, Tim ; Wevers, Martine ; Halbgebauer, Rebecca ; Huber-Lang, Markus ; Kerckhofs, Greet. X-Ray-Based 3D Histopathology of the Kidney Using Cryogenic Contrast-Enhanced MicroCT. In: International Journal of Biomedical Imaging, Vol. 2024, p. 3924036 (2024). doi:10.1155/2024/3924036.

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Pestiaux, Camille ; Pyka, Grzegorz ; Quirynen, Louise ; De Azevedo Coutinho Pereira, David ; Vanoverschelde, Jean-Louis ; Lengelé, Benoît ; Vancraeynest, David ; Beauloye, Christophe ; Kerckhofs, Greet. 3D histopathology of stenotic aortic valve cusps using ex vivo microfocus computed tomography. In: Frontiers in cardiovascular medicine, Vol. 10, p. 1129990 [1-15] (2023). doi:10.3389/fcvm.2023.1129990.

Sadeghian Dehkord, Ehsan ; Kerckhofs, Greet ; Compère, Philippe ; Lambert, France ; Geris, Liesbet. An Empirical Model Linking Physico-Chemical Biomaterial Characteristics to Intra-Oral Bone Formation. In: Journal of functional biomaterials, Vol. 14, no. 7, p. 388 [1-16] (2023). doi:10.3390/jfb14070388.

Starovoyt, Anastasiya ; Shaheen, Eman ; Putzeys, Tristan ; Kerckhofs, Greet ; Politis, Constantinus ; Wouters, Jan ; Verhaert, Nicolas. Anatomically and mechanically accurate scala tympani model for electrode insertion studies. In: Hearing research, Vol. 430, p. 108707 [1-11] (2023). doi:10.1016/j.heares.2023.108707.

Starovoyt, Anastasiya ; Pyka, Grzegorz ; Putzeys, Tristan ; Balcaen, Tim ; Wouters, Jan ; Kerckhofs, Greet ; Verhaert, Nicolas. Human cochlear microstructures at risk of electrode insertion trauma, elucidated in 3D with contrast-enhanced microCT. In: Scientific Reports, Vol. 13, no.1, p. - (2023). doi:10.1038/s41598-023-29401-6.

Leyssens, Lisa ; Balcaen, Tim ; Pétré, Maïté ; Bejar Ayllon, Natalia ; El Aazmani, Walid ; de Pierpont, Alix ; Pyka, Grzegorz ; Lacroix, Valérie ; Kerckhofs, Greet. Non-destructive 3D characterization of the blood vessel wall microstructure in different species and blood vessel types using contrast-enhanced microCT and comparison with synthetic vascular grafts. In: Acta biomaterialia, Vol. 164, p. 303-316 (2023). doi:10.1016/j.actbio.2023.04.013.

Benova, Andrea ; Ferencakova, Michaela ; Bardova, Kristina ; Funda, Jiri ; Prochazka, Jan ; Spoutil, Frantisek ; Cajka, Tomas ; Dzubanova, Martina ; Balcaen, Tim ; Kerckhofs, Greet ; Willekens, Wouter ; van Lenthe, G. Harry ; Charyyeva, Arzuv ; Alquicer, Glenda ; Pecinova, Alena ; Mracek, Tomas ; Horakova, Olga ; Coupeau, Roman ; Hansen, Morten Svarer ; Rossmeisl, Martin ; Kopecky, Jan ; Tencerova, Michaela. Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity. In: Communications Biology, Vol. 6, no.1, p. - (2023). doi:10.1038/s42003-023-05407-8.

Salmon, Phil L. ; Monzem, Samuel ; Javaheri, Behzad ; Oste, Line ; Kerckhofs, Greet ; Pitsillides, Andrew A.. Resolving trabecular metaphyseal bone profiles downstream of the growth plate adds value to bone histomorphometry in mouse models. In: Frontiers in endocrinology, Vol. 14, p. 1158099 [1-17] (2023). doi:10.3389/fendo.2023.1158099.

Balcaen, Tim ; Piens, Catherine ; Mwema, Ariane ; Chourrout, Matthieu ; Vandebroek, Laurens ; des Rieux, Anne ; Chauveau, Fabien ; De Borggraeve, Wim M. ; Hoffmann, Delia ; Kerckhofs, Greet. Revealing the three-dimensional murine brain microstructure by contrast-enhanced computed tomography. In: Frontiers in neuroscience, Vol. 17, p. 1141615 [1-15] (2023). doi:10.3389/fnins.2023.1141615.

Pestiaux, Camille ; Marino, Alice ; Simal, Lauriane ; Horman, Sandrine ; Capoulade, Romain ; Kerckhofs, Greet. X-ray-Based 3D Histology of Murine Hearts Using Contrast-Enhanced Microfocus Computed Tomography (CECT) and Cryo-CECT. In: Hearts, Vol. 5, no.1, p. 14-28 (2023). doi:10.3390/hearts5010002.

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Starovoyt, Anastasiya ; Quirk, Bryden C. ; Putzeys, Tristan ; Kerckhofs, Greet ; Nuyts, Johan ; Wouters, Jan ; McLaughlin, Robert A. ; Verhaert, Nicolas. An optically-guided cochlear implant sheath for real-time monitoring of electrode insertion into the human cochlea. In: Scientific Reports, Vol. 12, no.1, p. 19234 (2022). doi:10.1038/s41598-022-23653-4.

Maes, Arne ; Pestiaux, Camille ; Marino, Alice ; Balcaen, Tim ; Leyssens, Lisa ; Vangrunderbeeck, Sarah ; Pyka, Grzegorz ; De Borggraeve, Wim M. ; Bertrand, Luc ; Beauloye, Christophe ; Horman, Sandrine ; Wevers, Martine ; Kerckhofs, Greet. Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues. In: Nature communications, Vol. 13, no. 1, p. 6207 [1-14] (2022). doi:10.1038/s41467-022-34048-4.

Léger, Jean ; Leyssens, Lisa ; Kerckhofs, Greet ; De Vleeschouwer, Christophe. Ensemble learning and test-time augmentation for the segmentation of mineralized cartilage versus bone in high-resolution microCT images. In: Computers in Biology and Medicine, Vol. 148, no.-, p. 105932 (2022). doi:10.1016/j.compbiomed.2022.105932.

Ali, Dalia ; Figeac, Florence ; Caci, Atenisa ; Ditzel, Nicholas ; Schmal, Clarissa ; Kerckhofs, Greet ; Havelund, Jesper ; Færgeman, Nils ; Rauch, Alexander ; Tencerova, Michaela ; Kassem, Moustapha. High‐fat diet‐induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice. In: Aging Cell, Vol. -, no.-, p. - (2022). doi:10.1111/acel.13726.

Figeac, Florence ; Tencerova, Michaela ; Ali, Dalia ; Andersen, Thomas L ; Appadoo, Dan Rémi Christiansen ; Kerckhofs, Greet ; Ditzel, Nicholas ; Kowal, Justyna M ; Rauch, Alexander ; Kassem, Moustapha. Impaired bone fracture healing in type 2 diabetes is caused by defective functions of skeletal progenitor cells. In: Stem Cells, Vol. -, no.-, p. - (2022). doi:10.1093/stmcls/sxab011.

Benova, Andrea ; Ferencakova, Michaela ; Bardova, Kristina ; Funda, Jiri ; Prochazka, Jan ; Spoutil, Frantisek ; Cajka, Tomas ; Dzubanova, Martina ; Balcaen, Tim ; Kerckhofs, Greet ; Willekens, Wouter ; van Lenthe, G. Harry ; Alquicer, Glenda ; Pecinova, Alena ; Mracek, Tomas ; Horakova, Olga ; Rossmeisl, Martin ; Kopecky, Jan ; Tencerova, Michaela. Novel thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones. In: Molecular Metabolism, Vol. 65, no.-, p. 101598 (2022). doi:10.1016/j.molmet.2022.101598 (Accepté/Sous presse).

Frangi, Giulia ; Guicheteau, Marie ; Jacquot, Frederic ; Pyka, Grzegorz ; Kerckhofs, Greet ; Feyeux, Magalie ; Veziers, Joëlle ; Guihard, Pierre ; Halgand, Boris ; Sourice, Sophie ; Guicheux, Jérôme ; Prieur, Xavier ; Beck, Laurent ; Beck-Cormier, Sarah. PiT2 deficiency prevents increase of bone marrow adipose tissue during skeletal maturation but not in OVX-induced osteoporosis. In: Frontiers in Endocrinology, Vol. 13, p. 1-11 (2022). doi:10.3389/fendo.2022.921073.

Pascart, Tristan ; Falgayrac, Guillaume ; Cortet, Bernard ; Paccou, Julien ; Bleuse, Maverick ; Coursier, Raphaël ; Putman, Sophie ; Quinchon, Jean-François ; Bertheaume, Nicolas ; Delattre, Jerome ; Marchandise, Pierre ; Cultot, Aurélie ; Norberciak, Laurène ; Kerckhofs, Greet ; Budzik, Jean-François. Subchondral involvement in osteonecrosis of the femoral head: insight on local composition, microstructure and vascularization.. In: Osteoarthritis and cartilage, Vol. 30, no. 8, p. 1103-1115 (2022). doi:10.1016/j.joca.2022.05.003.

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Leyssens, Lisa ; Pestiaux, Camille ; Kerckhofs, Greet. A Review of Ex Vivo X-ray Microfocus Computed Tomography-Based Characterization of the Cardiovascular System. In: International Journal of Molecular Sciences, Vol. 22, no.6, p. 3263 (2021). doi:10.3390/ijms22063263.

Tam, Wai Long ; Freitas Mendes, Luís ; Chen, Xike ; Lesage, Raphaëlle ; Van Hoven, Inge ; Leysen, Elke ; Kerckhofs, Greet ; Bosmans, Kathleen ; Chai, Yoke Chin ; Yamashita, Akihiro ; Tsumaki, Noriyuki ; Geris, Liesbet ; Roberts, Scott J. ; Luyten, Frank P.. Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects. In: Stem Cell Research & Therapy, Vol. 12, no.1 (2021). doi:10.1186/s13287-021-02580-7.

Marin, Carlos ; Tuts, Jolien ; Luyten, Frank P. ; Vandamme, Katleen ; Kerckhofs, Greet. Impaired soft and hard callus formation during fracture healing in diet-induced obese mice as revealed by 3D contrast-enhanced computed tomography imaging. In: Bone, Vol. 150, no.-, p. 116008 (2021). doi:10.1016/j.bone.2021.116008.

de Bournonville, Sébastien ; Geris, Liesbet ; Kerckhofs, Greet. Micro computed tomography with and without contrast enhancement for the characterization of microcarriers in dry and wet state. In: Scientific Reports, Vol. 11, no. 1 (2021). doi:10.1038/s41598-021-81998-8.

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Colsoul, Nicolas ; Marin, Carlos ; Corbeels, Katrien ; Kerckhofs, Greet ; Van der Schueren, Bart ; Vandamme, Katleen. Alteration of the Condylar Oral Bone in Obese and Gastric Bypass Mice. In: Calcified Tissue International, Vol. 107, no.4, p. 371-380 (2020). doi:10.1007/s00223-020-00732-0.

Kamperman, Tom ; Teixeira, Liliana Moreira ; Salehi, Seyedeh Sarah ; Kerckhofs, Greet ; Guyot, Yann ; Geven, Mike ; Geris, Liesbet ; Grijpma, Dirk ; Blanquer, Sebastien ; Leijten, Jeroen. Engineering 3D parallelized microfluidic droplet generators with equal flow profiles by computational fluid dynamics and stereolithographic printing. In: Lab on a Chip, Vol. 20, no. 3, p. 490-495 (2020). doi:10.1039/c9lc00980a.

de Bournonville, Sébastien ; Vangrunderbeeck, Sarah ; Ly, Hong Giang T. ; Geeroms, Carla ; De Borggraeve, Wim M. ; Parac-Vogt, Tatjana N. ; Kerckhofs, Greet. Exploring polyoxometalates as non-destructive staining agents for contrast-enhanced microfocus computed tomography of biological tissues. In: Acta Biomaterialia, Vol. 105, p. 253-262 (2020). doi:10.1016/j.actbio.2020.01.038.

Tratwal, Josefine ; Labella, Rossella ; Bravenboer, Nathalie ; Kerckhofs, Greet ; Douni, Eleni ; Scheller, Erica L. ; Badr, Sammy ; Karampinos, Dimitrios C. ; Beck-Cormier, Sarah ; Palmisano, Biagio ; Poloni, Antonella ; Moreno-Aliaga, Maria J. ; Fretz, Jackie ; Rodeheffer, Matthew S. ; Boroumand, Parastoo ; Rosen, Clifford J. ; Horowitz, Mark C. ; van der Eerden, Bram C. J. ; Veldhuis-Vlug, Annegreet G. ; Naveiras, Olaia. Reporting Guidelines, Review of Methodological Standards, and Challenges Toward Harmonization in Bone Marrow Adiposity Research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society. In: Frontiers in Endocrinology, Vol. 11, p. 65 [1-36] (2020). doi:10.3389/fendo.2020.00065.

Pascart, Tristan ; Paccou, Julien ; Colard, Thomas ; Norberciak, Laurène ; Girard, Julien ; Delattre, Jerôme ; Marchandise, Pierre ; Legrand, Julie ; Penel, Guillaume ; Coursier, Raphaël ; Putman, Sophie ; Cortet, Bernard ; Kerckhofs, Greet ; Budzik, Jean-François. T1-weighted MRI images accurately represent the volume and surface of architectural mineral damage of osteonecrosis of the femoral head: Comparison with high-resolution computed tomography. In: Bone, Vol. 130, p. 115099 (2020). doi:10.1016/j.bone.2019.115099.

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Penel, Guillaume ; Kerckhofs, Greet ; Chauveau, Christophe. Brief Report From the 4th International Meeting on Bone Marrow Adiposity (BMA2018). In: Frontiers in Endocrinology, Vol. 10 (2019). doi:10.3389/fendo.2019.00691.

de Bournonville, Sébastien ; Vangrunderbeeck, Sarah ; Kerckhofs, Greet. Contrast-Enhanced MicroCT for Virtual 3D Anatomical Pathology of Biological Tissues: A Literature Review. In: Contrast Media & Molecular Imaging, Vol. 2019, no.-, p. 1-9 (2019). doi:10.1155/2019/8617406.

Zhao, Lv ; Ding, Lipeng ; Soete, Jeroen ; Idrissi, Hosni ; Kerckhofs, Greet ; Simar, Aude. Fostering crack deviation via local internal stresses in Al/NiTi composites and its correlation with fracture toughness. In: Composites Part A: Applied Science and Manufacturing, Vol. 126, p. 105617 (2019). doi:10.1016/j.compositesa.2019.105617.

De Clercq, Katrien ; Persoons, Eleonora ; Napso, Tina ; Luyten, Catherine ; Parac-Vogt, Tatjana N. ; Sferruzzi-Perri, Amanda N. ; Kerckhofs, Greet ; Vriens, Joris. High-resolution contrast-enhanced microCT reveals the true three-dimensional morphology of the murine placenta. In: Proceedings of the National Academy of Sciences, Vol. -, no.-, p. 201902688 (2019). doi:10.1073/pnas.1902688116.

Bolette, Adrien ; Lecloux, Geoffrey ; Rompen, Eric ; Albert, Adelin ; Kerckhofs, Greet ; Lambert, France. Influence of induced infection in medication-related osteonecrosis of the jaw development after tooth extraction: a study in rats. In: Journal of Cranio-Maxillofacial Surgery, Vol. 47, no. 2, p. 349-356 (2019). doi:10.1016/j.jcms.2018.08.011.

Coutel, Xavier ; Delattre, Jérôme ; Marchandise, Pierre ; Falgayrac, Guillaume ; Béhal, Hélène ; Kerckhofs, Greet ; Penel, Guillaume ; Olejnik, Cécile. Mandibular bone is protected against microarchitectural alterations and bone marrow adipose conversion in ovariectomized rats. In: Bone, Vol. 127, p. 343-352 (2019). doi:10.1016/j.bone.2019.06.031.

Beekman, Kerensa M. ; Zwaagstra, Marleen ; Veldhuis-Vlug, Annegreet G. ; van Essen, Huib W. ; den Heijer, Martin ; Maas, Mario ; Kerckhofs, Greet ; Parac-Vogt, Tatjana N. ; Bisschop, Peter H. ; Bravenboer, Nathalie. Ovariectomy increases RANKL protein expression in bone marrow adipocytes of C3H/HeJ mice. In: American Journal of Physiology-Endocrinology and Metabolism, Vol. 317, no.6, p. E1050-E1054 (2019). doi:10.1152/ajpendo.00142.2019.

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Coutel, Xavier ; Olejnik, Cécile ; Marchandise, Pierre ; Delattre, Jérôme ; Béhal, Hélène ; Kerckhofs, Greet ; Penel, Guillaume. A Novel microCT Method for Bone and Marrow Adipose Tissue Alignment Identifies Key Differences Between Mandible and Tibia in Rats.. In: Calcified tissue international, Vol. 103, no. 2, p. 189-197 (2018). doi:10.1007/s00223-018-0397-1.

Cao, Wenchao ; Sun, Tao ; Kerckhofs, Greet ; Fardell, Gemma ; Price, Ben ; Dewulf, Wim. A simulation-based study on the influence of the x-ray spectrum on the performance of multi-material beam hardening correction algorithms. In: Measurement Science and Technology, Vol. 29, no. 9, p. 095002 (2018). doi:10.1088/1361-6501/aacba0.

Ji, Wei ; Kerckhofs, Greet ; Geeroms, Carla ; Marechal, Marina ; Geris, Liesbet ; Luyten, Frank P. Deciphering the combined effect of bone morphogenetic protein 6 and calcium phosphate on bone formation capacity of periosteum derived cells-based tissue engineering constructs.. In: Acta biomaterialia, Vol. 80, p. 97-107 (2018). doi:10.1016/j.actbio.2018.09.046.

Kerckhofs, Greet ; Stegen, Steve ; van Gastel, Nick ; Sap, Annelies ; Falgayrac, Guillaume ; Penel, Guillaume ; Durand, Marjorie ; Luyten, Frank ; Geris, Liesbet ; Vandamme, Katleen ; Parac-Vogt, Tatjana ; Carmeliet, Geert. Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure. In: Biomaterials, Vol. 159, no.-, p. 1-12 (2018). doi:10.1016/j.biomaterials.2017.12.016.

Beekman, Kerensa M. ; Veldhuis-Vlug, Annegreet G. ; van der Veen, Albert ; den Heijer, Martin ; Maas, Mario ; Kerckhofs, Greet ; Parac-Vogt, Tatjana N. ; Bisschop, Peter H ; Bravenboer, Nathalie. The effect of PPARγ inhibition on bone marrow adipose tissue and bone in C3H/HeJ mice.. In: American Journal of Physiology-Endocrinology and Metabolism, Vol. 316, no. 1, p. E96-E105 (2019). doi:10.1152/ajpendo.00265.2018.

Marin, Carlos ; Luyten, Frank ; Van Der Schueren, Bart ; Kerckhofs, Greet ; Vandamme, Katleen. The impact of type 2 diabetes on bone fracture healing. In: Frontiers in Endocrinology, Vol. 9, no. 6 (2018). doi:10.3389/fendo.2018.00006.

Marin, Carlos ; Papantonakis, Georgios ; Sels, Kathleen ; van Lenthe, G Harry ; Falgayrac, Guillaume ; Vangoitsenhoven, Roman ; Van der Schueren, Bart ; Penel, Guillaume ; Luyten, Frank ; Vandamme, Katleen ; Kerckhofs, Greet. Unraveling the compromised biomechanical performance of type 2 diabetes- and Roux-en-Y gastric bypass bone by linking mechanical-structural and physico-chemical properties.. In: Scientific Reports, Vol. 8, no.1, p. 5881 (2018). doi:10.1038/s41598-018-24229-x.

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Wevers, Martine ; Nicolai, Bart ; Verboven, Pieter ; Swennen, Rudy ; Roels, Staf ; Verstrynge, Els ; Lomov, Stepan Vladimirovitch ; Kerckhofs, Greet ; Van Meerbeek, Bart ; Mavridou, Athina ; Bergmans, Lars ; Lambrechts, Paul ; Soete, Jeroen ; Claes, Steven ; Claes, Hannes. Applications of CT for non-destructive testing and materials characterization. In: Carmignato, Simone ; Dewulf, Wim ; Leach, Richard, Industrial X-Ray Computed Tomography, Springer, 2018, p. 267-331. 978-3-319-59571-9.

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Manhas, Varun ; Guyot, Yann ; Kerckhofs, Greet ; Chai, Yoke Chin ; Geris, Liesbet. Computational modelling of local calcium ions release from calcium phosphate-based scaffolds. In: Biomechanics and Modeling in Mechanobiology, Vol. 16, no.2, p. 425-438 (2017). doi:10.1007/s10237-016-0827-9.

Guns, Laura-An ; Monteagudo, Silvia ; Kvasnytsia, Maryna ; Kerckhofs, Greet ; Vandooren, Jennifer ; Opdenakker, Ghislain ; Lories, Rik ; Cailotto, Frederic. Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo. In: RMD Open, Vol. 3, no.2, p. e000604 (2017). doi:10.1136/rmdopen-2017-000604.

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Mavridou, Athina ; Pyka, G ; Kerckhofs, Greet ; Wevers, Martine ; Bergmans, Lars ; Gunst, Veerle ; Huybrechts, Bart ; Schepers, Evert ; Hauben, Esther ; Lambrechts, Paul. A novel multimodular methodology to investigate external cervical tooth resorption. In: International Endodontic Journal, Vol. 49, no.3, p. 287-300 (2016). doi:10.1111/iej.12450.

Kerckhofs, Greet ; Durand, Marjorie ; Vangoitsenhoven, Roman ; Marin, Carlos ; Van Der Schueren, Bart ; Carmeliet, Geert ; Luyten, Frank ; Geris, Liesbet ; Vandamme, Katleen. Changes in bone macro- and microstructure in diabetic obese mice revealed by high resolution microfocus X-ray computed tomography. In: Scientific Reports, Vol. 6, no.35517, p. - (2016). doi:10.1038/srep35517.

Kerckhofs, Greet ; Chai, Y C ; Luyten, F P ; Geris, Liesbet. Combining microCT-based characterization with empirical modelling as a robust screening approach for the design of optimized CaP-containing scaffolds for progenitor cell-mediated bone formation. In: Acta Biomaterialia, Vol. 35, no.-, p. 330-340 (2016). doi:10.1016/j.actbio.2016.02.037.

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Sonnaert, Maarten ; Kerckhofs, Greet ; Papantoniou, Ioannis ; Van Vlierberghe, Sandra ; Boterberg, Veerle ; Dubruel, Peter ; Luyten, Frank ; Schrooten, Jan ; Geris, Liesbet. Multifactorial Optimization of Contrast-Enhanced Nanofocus Computed Tomography for Quantitative Analysis of Neo-Tissue Formation in Tissue Engineering Constructs. In: PLoS One, Vol. 10, no.6, p. 1-17 (2015). doi:10.1371/journal.pone.0130227.

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Kerckhofs, Greet ; Sainz, Julie ; Marechal, Marina ; Wevers, Martine ; Van de Putte, Tom ; Geris, Liesbet ; Schrooten, Jan. Contrast-enhanced nanofocus X-ray computed tomography allows virtual three-dimensional histopathology and morphometric analysis of osteoarthritis in small animal models. In: Cartilage, Vol. 5, no.1, p. 55-65 (2014). doi:10.1177/1947603513501175.

Sonnaert, Maarten ; Papantoniou, Ioannis ; Bloemen, Veerle ; Kerckhofs, Greet ; Luyten, Frank ; Schrooten, Jan. Human periosteal-derived cell expansion in a perfusion bioreactor system: proliferation, differentiation and extracellular matrix formation. In: Journal of Tissue Engineering and Regenerative Medicine, Vol. 11, no.2, p. 519-530 (2014). doi:10.1002/term.1951.

Lambrechts, Dennis ; Roeffaers, Maarten ; Kerckhofs, Greet ; Hofkens, Johan ; Van de Putte, tom ; Schrooten, Jan ; Van Oosterwyck, Hans. Reporter cell activity within hydrogel constructs quantified from oxygen-independent bioluminescence. In: Biomaterials, Vol. 35, no.28, p. 8065-8077 (2014). doi:10.1016/j.biomaterials.2014.06.002.

Papantoniou, Ioannis ; Guyot, Yann ; Sonnaert, Maarten ; Kerckhofs, Greet ; Luyten, Frank ; Geris, Liesbet ; Schrooten, Jan. Spatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes. In: Biotechnology and Bioengineering, Vol. 111, no.12, p. 2560-70 (2014). doi:10.1002/bit.25303.

Pyka, Grzegorz ; Kerckhofs, Greet ; Schrooten, Jan ; Wevers, Martine. The effect of spatial micro-CT image resolution and surface complexity on the morphological 3D analysis of open porous structures. In: Materials Characterization, Vol. 87, p. 104-115 (2014). doi:10.1016/j.matchar.2013.11.004.

Papantoniou, Ioannis ; Sonnaert, Maarten ; Geris, Liesbet ; Luyten, Frank ; Schrooten, Jan ; Kerckhofs, Greet. Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography. In: Tissue Engineering Part C, Methods, Vol. 20, no.3, p. 177-187 (2014).

journalArticle

Kerckhofs, Greet ; Sainz, Julie ; Wevers, Martine ; Van de Putte, Tom ; Schrooten, Jan. Contrast-enhanced nanofocus computed tomography images the cartilage subtissue architecture in three dimensions. In: European Cells & Materials, Vol. 25, no.-, p. 179-189 (2013).

Lambrechts, Dennis ; Roeffaers, Maarten ; Kerckhofs, Greet ; Roberts, Scott ; Hofkens, Johan ; Van de Putte, Tom ; Van Oosterwyck, Hans ; Schrooten, Jan. Fluorescent oxygen sensitive microbead incorporation for measuring oxygen tension in cell aggregates. In: Biomaterials, Vol. 34, no. 4, p. 922-929 (2013).

Kerckhofs, Greet ; Pyka, Grzegorz ; Moesen, Maarten ; Van Bael, Simon ; Schrooten, Jan ; Wevers, Martine. High-resolution microfocus X-ray computed tomography for 3D surface roughness measurements of additive manufactured porous materials. In: Advanced Engineering Materials, Vol. 15, no.3, p. 153-158 (2013). doi:10.1002/adem.201200156.

Pyka, Grzegorz ; Kerckhofs, Greet ; Papantoniou, Ioannis ; Speirs, Mathew ; Schrooten, Jan ; Wevers, Martine. Surface roughness and morphology customization of additive manufactured open porous Ti6Al4V structures. In: Materials, Vol. 6, no.-, p. 4737-4757 (2013). doi:10.3390/ma6104737.

Karunratanakul, Kavin ; Kerckhofs, Greet ; Lammens, Johan ; Vanlauwe, Johan ; Schrooten, Jan ; Van Oosterwyck, Hans. Validation of a finite element model of a unilateral external fixator in a rabbit tibia defect model. In: Medical Engineering & Physics, Vol. 35, no.7, p. 1037-1043 (2013). doi:10.1016/j.medengphy.2012.10.006.

journalArticle

Chai, Yoke Chin ; Kerckhofs, Greet ; Roberts, Scott ; Van Bael, Simon ; Schepers, Evert ; Vleugels, Jef ; Luyten, Frank ; Schrooten, Jan. Ectopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition. In: Biomaterials, Vol. 33, no. 16, p. 4044-4058 (2012).

Pfeiffer, Helge ; Heer, Peter ; Pitropakis, Ioannis ; Pyka, Grzegorz ; Kerckhofs, Greet ; Patitsa, Maria ; Wevers, Martine. Liquid detection in confined aircraft structures based on lyotropic percolation thresholds. In: Sensors and Actuators B, Chemical, Vol. 161, no.1, p. 791-798 (2012).

Chai, Yoke Chin ; Roberts, Scott J ; Desmet, Eline ; Kerckhofs, Greet ; van Gastel, Nick ; Geris, Liesbet ; Carmeliet, Geert ; Schrooten, Jan ; Luyten, Frank. Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers. In: Biomaterials, Vol. 33, no. 11, p. 3127-3142 (2012). doi:10.1016/j.biomaterials.2012.01.015.

Alam, Khurshid ; Kerckhofs, Greet ; Mitrofanov, Alexander ; Lomov, Stepan Vladimirovitch ; Wevers, Martine ; Silberschmidt, Viladimir Vadim. On-line analysis of cracking in cortical bone under wedge penetration. In: Proceedings of the Institution of Mechanical Engineers H, Journal of Engineering in Medicine, Vol. 226, no.H9, p. 709-717 (2012).

Truscello, Silvia ; Kerckhofs, Greet ; Van Bael, Simon ; Pyka, Grzegorz ; Schrooten, Jan ; Van Oosterwyck, Hans. Prediction of permeability of regular scaffolds for skeletal tissue engineering: A combined computational and experimental study. In: Acta Biomaterialia, Vol. 8, no.4, p. 1648-1658 (2012). doi:10.1016/j.actbio.2011.12.021.

Pyka, Grzegorz ; Burakowski, Andrzej ; Kerckhofs, Greet ; Moesen, Maarten ; Van Bael, Simon ; Schrooten, Jan ; Wevers, Martine. Surface modification of Ti6Al4V open porous structures produced by additive manufacturing. In: Advanced Engineering Materials, Vol. 14, no.6, p. 363-370 (2012). doi:10.1002/adem.201100344.

Van Bael, Simon ; Chai, Yoke Chin ; Truscello, Silvia ; Moesen, Maarten ; Kerckhofs, Greet ; Van Oosterwyck, Hans ; Kruth, Jean-Pierre ; Schrooten, Jan. The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser melted Ti6Al4V bone scaffolds. In: Acta Biomaterialia, Vol. 8, no.7, p. 2824-2834 (2012). doi:10.1016/j.actbio.2012.04.001.

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Van Bael, Simon ; Kerckhofs, Greet ; Moesen, Maarten ; Pyka, Grzegorz ; Schrooten, Jan ; Kruth, Jean-Pierre. Micro-CT-based improvement of geometrical and mechanical controllability of selective laser melted Ti6Al4V porous structures. In: Materials Science and Engineering A, Structural Materials: Properties, Microstructure and Processing, Vol. 528, no.24, p. 7423-7431 (2011).

Roberts, Scott ; Geris, Liesbet ; Kerckhofs, Greet ; Desmet, Eline ; Schrooten, Jan ; Luyten, Frank. The combined bone forming capacity of human periosteal derived cells and calcium phosphates. In: Biomaterials, Vol. 32, no.19, p. 4393-4405 (2011).

bookChapter

Verboven, P. ; Ho, Q. ; Herremans, E. ; Mebatsion, H. ; Nicolai, B. ; Kerckhofs, Greet ; Wevers, M. ; Cloetens, P.. Fruit Microstructure Evaluation Using Synchrotron X-Ray Computed Tomography. In: Aguilera J., Barbosa-Canovas G., Simpson R., Welti-Chanes J., Berludez-Aguirre D. (Eds.), Food Engineering Interfaces, Springer: New York, 2011, p. Chapter 24. 978-1-4419-7475-4.

journalArticle

Wilderjans, Edith ; Kerckhofs, Greet ; Lagrain, Bert ; Brijs, Kristof ; Wevers, Martine ; Delcour, Jan. Baking gradients cause heterogeneity in starch and proteins in pound cake. In: Cereal Chemistry, Vol. 87, no. 5, p. 475-480 (2010).

Neirinck, Bram ; Kerckhofs, Greet ; Wevers, Martine ; Van der Biest, Omer ; Vleugels, Jef. Morphological analysis of slip-cast emulsion-templated alumina foams by microfocus computer tomography. In: Journal of the American Ceramic Society, Vol. 93, no.11, p. 3921-3928 (2010).

Mendoza, Fernando ; Verboven, Pieter ; Tri Ho, Quang ; Kerckhofs, Greet ; Wevers, Martine ; Nicolai, Bart. Multifractal properties of pore-size distribution in apple tissue using X-ray imaging. In: Journal of Food Engineering, Vol. 99, no.-, p. 206-215 (2010).

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Pareyt, Bram ; Talhaoui, Faisal ; Kerckhofs, Greet ; Brijs, Kristof ; Goesaert, Hans ; Wevers, Martine ; Delcour, Jan. The role of sugar and fat in sugar-snap cookies: Structural and textural properties. In: Journal of food engineering, Vol. 90, no.3, p. 400-408 (2009). doi:10.1016/j.jfoodeng.2008.07.010.

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Léonard, Angélique ; Calberg, Cedric ; Kerckhofs, Greet ; Wevers, Martine ; Jérôme, Robert ; Pirard, Jean-Paul ; Germain, Albert ; Blacher, Silvia. Characterization of the porous structure of biodegradable scaffolds obtained with supercritical CO2 as foaming agent. In: Journal of porous materials, Vol. 15, no.4, p. 397-403 (2008).

Verboven, Pieter ; Kerckhofs, Greet ; Mebatsion, Hibru ; Ho, Quang Tri ; Temst, Kristiaan ; Wevers, Martine ; Cloetens, Peter ; Nicolai, Bart. Three-dimensional gas exchange pathways in pome fruit characterized by synchrotron X-ray computed tomography. In: Plant Physiology, Vol. 147, no.2, p. 518-527 (2008).

Kerckhofs, Greet ; Schrooten, Jan ; Van Cleynenbreugel, T ; Lomov, Stepan Vladimirovitch ; Wevers, Martine. Validation of x-ray microfocus computed tomography as an imaging tool for porous structures. In: Review of scientific instruments, Vol. 79, no.1, p. 013711-1-013711-9 (2008).

journalArticle

Mendoza, Fernando ; Verboven, Pieter ; Mebatsion, Hibru Kelemu ; Kerckhofs, Greet ; Wevers, Martine ; Nicolai, Bart. Three-dimensional pore space quantification of apple tissue using X-ray computed microtomography. In: Planta, Vol. 226, no.3, p. 559-570 (2007).

journalArticle

Blacher, S. ; Calberg, C. ; Kerckhofs, Greet ; Leonard, A. ; Wevers, Martine ; Jerôme, R. ; Rirard, J.-P.. The porous structure of biodegradable scaffolds obtained with supercritical CO2 as foaming agent. In: Studies in Surface Science and Catalysis, Vol. 160, no.-, p. 681-688 (2006).

  • LGBIO1113 - Systems anatomy and physiology / Anatomie et physiologie des systèmes (FR)
  • LGBIO2040 - Biomechanics (ENG)
  • LGBIO2050 - Medical Imaging (ENG)
  • LGBIO2071 - Tissue Engineering (ENG)
  • LMECA2355 - Mechanical design in biomedical engineering (ENG)

Learning units for 2024

Label Code
Introduction to biomedical engineering LGBIO1112
Systems Anatomy and Physiology LGBIO1113
Biomechanics LGBIO2040
Medical Imaging LGBIO2050
Tissue Engineering LGBIO2071
Mechanical design in biomedical engineering LMECA2355