Journal article
Marino, A., Cumps, J., Guilbert, L., Geiser, A., Baufays, C., Ginion, A., Ferté, L., Battault, S., De Matos, F., Ambroise, J., Zuurbier, C. J., Lezoualch, F., Pestiaux, C., Pyka, G., Kerckhofs, G., Roderick, H. L., Bertrand, L., Horman, S., & Beauloye, C. (2026). Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice. Cardiovascular Research. Published. https://doi.org/10.1093/cvr/cvag040 (Original work published 2026)
Journal article
Hoffmann, D., Balcaen, T., Vangrunderbeeck, S., Puigdevall Mata, L., Maes, A., Pyka, G., Dumoutier, L., Behets, C., De Borggraeve, W., & Kerckhofs, G. (2025). 3D Histological Analysis of Soft Tissues by Contrast-Enhanced X-Ray Microfocus Computed Tomography: Screening and Staining Optimization of Contrast-Enhancing Staining Agents. Microscopy and Microanalysis, 31(2). https://doi.org/10.1093/mam/ozaf013 (Original work published 2025)
Mazy, L., & Kerckhofs, G. (2025). A review of in-situ mechanical testing combined with X-ray microfocus computed tomography: Application and current challenges for biological tissues. Tomography of Materials and Structures, 8, 100062. https://doi.org/10.1016/j.tmater.2025.100062 (Original work published 2025)
Pétré, M., Wolfs, H., Lauranne Maes, Kerckhofs, G., & Nele Famaey. (2025). From microstructure to mechanics: A multi-constituent micro-scale computational model of arterial tissue. Computers in Biology and Medicine, 196(110816), Part C. https://doi.org/10.1016/j.compbiomed.2025.110816 (Original work published 2025)
Leyssens, L., El Aazmani, W., Balcaen, T., Jacques, P., Horman, S., Goldman, J., & Kerckhofs, G. (2025). MicroCT and contrast-enhanced microCT to study the in vivo degradation behavior and biocompatibility of candidate metallic intravascular stent materials. Acta Biomaterialia, 191, 53-65. https://doi.org/10.1016/j.actbio.2024.11.017 (Original work published 2025)
Morath, L., Rahim, S. A., Baker, C., Anderson, D. E. J., Hinds, M. T., Sikora-Jasinska, M., Oujiri, L., Leyssens, L., Kerckhofs, G., Pyka, G., Oliver, A. A., Drelich, J. W., & Goldman, J. (2025). The biological effects of copper alloying in Zn-based biodegradable arterial implants. Biomaterials Advances, 167, 214112. https://doi.org/10.1016/j.bioadv.2024.214112 (Original work published 2025)
Hanne, N. J., Steward, A. J., Geeroms, C., Easter, E. D., Gensch, H. T., Kerckhofs, G., Parac-Vogt, T. N., Sheng, H., & Cole, J. H. (2025). Ischemic stroke reduces bone perfusion and alters osteovascular structure. Bone Reports, 24, 101824. https://doi.org/10.1016/j.bonr.2025.101824 (Original work published 2025)
Chen, L., Shi, K., Ditzel, N., Qiu, W., Tencerova, M., Nielsen, L. H. D., Figeac, F., Rauch, A., Liu, Y., Tao, J., Sramkova, V., Rossmeislova, L., Kerckhofs, G., Parac-Vogt, T. N., de Bournonville, S., Andersen, T. L., Rydén, M., & Kassem, M. (2025). KIAA1199 (CEMIP) regulates adipogenesis and whole-body energy metabolism. Bone Research, 13(1). https://doi.org/10.1038/s41413-025-00415-2 (Original work published 2025)
Manon, J., Gillerot, E., Delandmeeter, F., Van den Broeck, L., Schneidewind, P., Coche, E., Pyka, G., Cornu, O., Behets, C., Kerckhofs, G., & Lengelé, B. (2025). Beneath the perforators: Unravelling fascia lata intrinsic vascular architecture using microfocus X-ray computed tomography. Annals of Anatomy, 259, 152386. https://doi.org/10.1016/j.aanat.2025.152386 (Original work published 2025)
Journal article
Pétré, M., Balcaen, T., Schneidewind, P., Mazy, L., Pyka, G., Fehervary, H., Famaey, N., & Kerckhofs, G. (2024). Screening staining agents for contrast-enhanced microCT of vascular tissues: Assessing the effect on microstructural and mechanical properties. Tomography of Materials and Structures, 6(100038), 100038. https://doi.org/10.1016/j.tmater.2024.100038 (Original work published 2024)
Balcaen, T., Benova, A., de Jong, F., de Oliveira Silva, R., Cajka, T., Sakellariou, D., Tencerova, M., Kerckhofs, G., & De Borggraeve, W. M. (2024). Exploring contrast-enhancing staining agents for studying adipose tissue through contrast-enhanced computed tomography. Journal of Lipid Research, 65(7), 100572. https://doi.org/10.1016/j.jlr.2024.100572 (Original work published 2024)
Xie, M., Kaiser, M., Gershtein, Y., Schnyder, D., Deviatiiarov, R., Gazizova, G., Shagimardanova, E., Zikmund, T., Kerckhofs, G., Ivashkin, E., Batkovskyte, D., Newton, P. T., Andersson, O., Fried, K., Gusev, O., Zeberg, H., Kaiser, J., Adameyko, I., & Chagin, A. S. (2024). The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling. Nat Commun, 15(1), 2367. https://doi.org/10.1038/s41467-024-46030-3 (Original work published 2024)
Docter, D., Timmerman, M., Dawood, Y., Hagoort, J., Lobe, N., van Heurn, E., Gorter, R., Jacobs, K., Pyka, G., Kerckhofs, G., van den Hoff, M. J. B., & de Bakker, B. (2024). Scaling up contrast-enhanced micro-CT imaging: Optimizing contrast and acquisition for large ex-vivo human samples. Forensic Imaging, 37, 200596 [1-8]. https://doi.org/10.1016/j.fri.2024.200596 (Original work published 2024)
Saraiva Rocha da Silva, F., Georgiadis, C., Van Droogenbroek, K., Delmelle, R., Pinon, X., Pyka, G., Kerckhofs, G., Egert, F., Razmjooei, F., Ansar, S.-A., Mitsushima, S., & Proost, J. (2024). Proton exchange membrane-like alkaline water electrolysis using flow-engineered three-dimensional electrodes. Nature Communications, 15, 7444. https://hdl.handle.net/2078.5/241068 (Original work published 2024)
Muylle, E., Maes, A., De Hertogh, G., Van De Winkel, N., Kerckhofs, G., Dubois, A., Vandecaveye, V., Thorrez, L., Hennion, I., Emonds, M.-P., Pans, S., Deferm, N. P., Monbaliu, D., Canovai, E., Vanuytsel, T., Pirenne, J., & Ceulemans, L. J. (2024). Multilevel Analysis of the Neovascularization and Integration Process of a Nonvascularized Rectus Fascia Transplantation. Transplantation Direct, 10(6), e1624. https://doi.org/10.1097/txd.0000000000001624 (Original work published 2024)
Davis, S., Karali, A., Balcaen, T., Zekonyte, J., Pétré, M., Roldo, M., Kerckhofs, G., & Blunn, G. (2024). Comparison of two contrast-enhancing staining agents for use in X-ray imaging and digital volume correlation measurements across the cartilage-bone interface. Journal of the Mechanical Behavior of Biomedical Materials, 152, 106414. https://doi.org/10.1016/j.jmbbm.2024.106414 (Original work published 2024)
Maes, A., Borgel, O., Braconnier, C., Balcaen, T., Wevers, M., Halbgebauer, R., Huber-Lang, M., & Kerckhofs, G. (2024). X-Ray-Based 3D Histopathology of the Kidney Using Cryogenic Contrast-Enhanced MicroCT. International Journal of Biomedical Imaging, 2024, 3924036. https://doi.org/10.1155/2024/3924036 (Original work published 2024)
Lang, A., Benn, A., Collins, J. M., Wolter, A., Balcaen, T., Kerckhofs, G., Zwijsen, A., & Boerckel, J. D. (2024). Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone. Communications biology, 7(1), 315 [1-13]. https://doi.org/10.1038/s42003-024-05915-1 (Original work published 2024)
Manon, J., Gallant, L., Gérard, P., Fievé, L., Schneidewind, P., Pyka, G., Kerckhofs, G., Lengelé, B., Cornu, O., & Behets Wydemans, C. (2024). 2D and 3D microstructural analysis of the iliotibial tract. Journal of anatomy, 245(5), 725-739. https://doi.org/10.1111/joa.14125 (Original work published 2024)
Leyssens, L., Lapraille, N., Pyka, G., Jacques, P., Horman, S., Goldman, J., & Kerckhofs, G. (2024). Exploring the biodegradability of candidate metallic intravascular stent materials using X-ray microfocus computed tomography: An in vitro study. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 112(8), e35452. https://doi.org/10.1002/jbm.b.35452 (Original work published 2024)
Journal article
Sadeghian Dehkord, E., Kerckhofs, G., Compère, P., Lambert, F., & Geris, L. (2023). An Empirical Model Linking Physico-Chemical Biomaterial Characteristics to Intra-Oral Bone Formation. Journal of Functional Biomaterials, 14(7), 388 [1-16]. https://doi.org/10.3390/jfb14070388 (Original work published 2023)
Pestiaux, C., Marino, A., Simal, L., Horman, S., Capoulade, R., & Kerckhofs, G. (2023). X-ray-Based 3D Histology of Murine Hearts Using Contrast-Enhanced Microfocus Computed Tomography (CECT) and Cryo-CECT. Information (Basel), 5(1), 14-28. https://doi.org/10.3390/hearts5010002 (Original work published 2023)
Starovoyt, A., Shaheen, E., Putzeys, T., Kerckhofs, G., Politis, C., Wouters, J., & Verhaert, N. (2023). Anatomically and mechanically accurate scala tympani model for electrode insertion studies. Hearing Research, 430, 108707 [1-11]. https://doi.org/10.1016/j.heares.2023.108707 (Original work published 2023)
Benova, A., Ferencakova, M., Bardova, K., Funda, J., Prochazka, J., Spoutil, F., Cajka, T., Dzubanova, M., Balcaen, T., Kerckhofs, G., Willekens, W., van Lenthe, G. H., Charyyeva, A., Alquicer, G., Pecinova, A., Mracek, T., Horakova, O., Coupeau, R., Hansen, M. S., et al. (2023). Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity. Communications Biology, 6(1). https://doi.org/10.1038/s42003-023-05407-8 (Original work published 2023)
Salmon, P. L., Monzem, S., Javaheri, B., Oste, L., Kerckhofs, G., & Pitsillides, A. A. (2023). Resolving trabecular metaphyseal bone profiles downstream of the growth plate adds value to bone histomorphometry in mouse models. Frontiers in Endocrinology, 14, 1158099 [1-17]. https://doi.org/10.3389/fendo.2023.1158099 (Original work published 2023)
Leyssens, L., Balcaen, T., Pétré, M., Bejar Ayllon, N., El Aazmani, W., de Pierpont, A., Pyka, G., Lacroix, V., Kerckhofs, G., & et al. (2023). Non-destructive 3D characterization of the blood vessel wall microstructure in different species and blood vessel types using contrast-enhanced microCT and comparison with synthetic vascular grafts. Acta Biomaterialia, 164, 303-316. https://doi.org/10.1016/j.actbio.2023.04.013 (Original work published 2023)
Pestiaux, C., Pyka, G., Quirynen, L., De Azevedo Coutinho Pereira, D., Vanoverschelde, J.-L., Lengelé, B., Vancraeynest, D., Beauloye, C., & Kerckhofs, G. (2023). 3D histopathology of stenotic aortic valve cusps using ex vivo microfocus computed tomography. Frontiers in Cardiovascular Medicine, 10, 1129990 [1-15]. https://doi.org/10.3389/fcvm.2023.1129990 (Original work published 2023)
Balcaen, T., Piens, C., Mwema, A., Chourrout, M., Vandebroek, L., des Rieux, A., Chauveau, F., De Borggraeve, W. M., Hoffmann, D., & Kerckhofs, G. (2023). Revealing the three-dimensional murine brain microstructure by contrast-enhanced computed tomography. Frontiers in neuroscience, 17, 1141615 [1-15]. https://doi.org/10.3389/fnins.2023.1141615 (Original work published 2023)
Starovoyt, A., Pyka, G., Putzeys, T., Balcaen, T., Wouters, J., Kerckhofs, G., & Verhaert, N. (2023). Human cochlear microstructures at risk of electrode insertion trauma, elucidated in 3D with contrast-enhanced microCT. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-29401-6 (Original work published 2023)
Journal article
Starovoyt, A., Quirk, B. C., Putzeys, T., Kerckhofs, G., Nuyts, J., Wouters, J., McLaughlin, R. A., & Verhaert, N. (2022). An optically-guided cochlear implant sheath for real-time monitoring of electrode insertion into the human cochlea. Scientific Reports, 12(1), 19234. https://doi.org/10.1038/s41598-022-23653-4 (Original work published 2022)
Maes, A., Pestiaux, C., Marino, A., Balcaen, T., Leyssens, L., Vangrunderbeeck, S., Pyka, G., De Borggraeve, W. M., Bertrand, L., Beauloye, C., Horman, S., Wevers, M., & Kerckhofs, G. (2022). Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues. Nature Communications, 13(1), 6207 [1-14]. https://doi.org/10.1038/s41467-022-34048-4 (Original work published 2022)
Figeac, F., Tencerova, M., Ali, D., Andersen, T. L., Appadoo, D. R. C., Kerckhofs, G., Ditzel, N., Kowal, J. M., Rauch, A., & Kassem, M. (2022). Impaired bone fracture healing in type 2 diabetes is caused by defective functions of skeletal progenitor cells. Stem Cells : the international journal of cell differentiation and proliferation. Published. https://doi.org/10.1093/stmcls/sxab011 (Original work published 2022)
Pascart, T., Falgayrac, G., Cortet, B., Paccou, J., Bleuse, M., Coursier, R., Putman, S., Quinchon, J.-F., Bertheaume, N., Delattre, J., Marchandise, P., Cultot, A., Norberciak, L., Kerckhofs, G., & Budzik, J.-F. (2022). Subchondral involvement in osteonecrosis of the femoral head: insight on local composition, microstructure and vascularization. Osteoarthritis and Cartilage, 30(8), 1103-1115. https://doi.org/10.1016/j.joca.2022.05.003 (Original work published 2022)
Benova, A., Ferencakova, M., Bardova, K., Funda, J., Prochazka, J., Spoutil, F., Cajka, T., Dzubanova, M., Balcaen, T., Kerckhofs, G., Willekens, W., van Lenthe, G. H., Alquicer, G., Pecinova, A., Mracek, T., Horakova, O., Rossmeisl, M., Kopecky, J., & Tencerova, M. (2022). Novel thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones. Molecular Metabolism, 65, 101598. https://doi.org/10.1016/j.molmet.2022.101598 (Original work published 2022)
Frangi, G., Guicheteau, M., Jacquot, F., Pyka, G., Kerckhofs, G., Feyeux, M., Veziers, J., Guihard, P., Halgand, B., Sourice, S., Guicheux, J., Prieur, X., Beck, L., & Beck-Cormier, S. (2022). PiT2 deficiency prevents increase of bone marrow adipose tissue during skeletal maturation but not in OVX-induced osteoporosis. Frontiers in Endocrinology, 13, 1-11. https://doi.org/10.3389/fendo.2022.921073 (Original work published 2022)
Ali, D., Figeac, F., Caci, A., Ditzel, N., Schmal, C., Kerckhofs, G., Havelund, J., Færgeman, N., Rauch, A., Tencerova, M., & Kassem, M. (2022). High‐fat diet‐induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice. Aging Cell. Published. https://doi.org/10.1111/acel.13726 (Original work published 2022)
Léger, J., Leyssens, L., Kerckhofs, G., & De Vleeschouwer, C. (2022). Ensemble learning and test-time augmentation for the segmentation of mineralized cartilage versus bone in high-resolution microCT images. Computers in Biology and Medicine, 148, 105932. https://doi.org/10.1016/j.compbiomed.2022.105932 (Original work published 2022)
Journal article
Marin, C., Tuts, J., Luyten, F. P., Vandamme, K., & Kerckhofs, G. (2021). Impaired soft and hard callus formation during fracture healing in diet-induced obese mice as revealed by 3D contrast-enhanced computed tomography imaging. Bone, 150, 116008. https://doi.org/10.1016/j.bone.2021.116008 (Original work published 2021)
Leyssens, L., Pestiaux, C., & Kerckhofs, G. (2021). A Review of Ex Vivo X-ray Microfocus Computed Tomography-Based Characterization of the Cardiovascular System. International Journal of Molecular Sciences, 22(6), 3263. https://doi.org/10.3390/ijms22063263 (Original work published 2021)
Tam, W. L., Freitas Mendes, L., Chen, X., Lesage, R., Van Hoven, I., Leysen, E., Kerckhofs, G., Bosmans, K., Chai, Y. C., Yamashita, A., Tsumaki, N., Geris, L., Roberts, S. J., & Luyten, F. P. (2021). Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects. Stem Cell Research & Therapy, 12(1). https://doi.org/10.1186/s13287-021-02580-7 (Original work published 2021)
de Bournonville, S., Geris, L., & Kerckhofs, G. (2021). Micro computed tomography with and without contrast enhancement for the characterization of microcarriers in dry and wet state. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-81998-8 (Original work published 2021)
Journal article
Kamperman, T., Teixeira, L. M., Salehi, S. S., Kerckhofs, G., Guyot, Y., Geven, M., Geris, L., Grijpma, D., Blanquer, S., & Leijten, J. (2020). Engineering 3D parallelized microfluidic droplet generators with equal flow profiles by computational fluid dynamics and stereolithographic printing. Lab on a Chip, 20(3), 490-495. https://doi.org/10.1039/c9lc00980a (Original work published 2020)
de Bournonville, S., Vangrunderbeeck, S., Ly, H. G. T., Geeroms, C., De Borggraeve, W. M., Parac-Vogt, T. N., & Kerckhofs, G. (2020). Exploring polyoxometalates as non-destructive staining agents for contrast-enhanced microfocus computed tomography of biological tissues. Acta Biomaterialia, 105, 253-262. https://doi.org/10.1016/j.actbio.2020.01.038 (Original work published 2020)
Tratwal, J., Labella, R., Bravenboer, N., Kerckhofs, G., Douni, E., Scheller, E. L., Badr, S., Karampinos, D. C., Beck-Cormier, S., Palmisano, B., Poloni, A., Moreno-Aliaga, M. J., Fretz, J., Rodeheffer, M. S., Boroumand, P., Rosen, C. J., Horowitz, M. C., van der Eerden, B. C. J., Veldhuis-Vlug, A. G., & Naveiras, O. (2020). Reporting Guidelines, Review of Methodological Standards, and Challenges Toward Harmonization in Bone Marrow Adiposity Research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society. Frontiers in Endocrinology, 11, 65 [1-36]. https://doi.org/10.3389/fendo.2020.00065 (Original work published 2020)
Pascart, T., Paccou, J., Colard, T., Norberciak, L., Girard, J., Delattre, J., Marchandise, P., Legrand, J., Penel, G., Coursier, R., Putman, S., Cortet, B., Kerckhofs, G., & Budzik, J.-F. (2020). T1-weighted MRI images accurately represent the volume and surface of architectural mineral damage of osteonecrosis of the femoral head: Comparison with high-resolution computed tomography. Bone, 130, 115099. https://doi.org/10.1016/j.bone.2019.115099 (Original work published 2020)
Colsoul, N., Marin, C., Corbeels, K., Kerckhofs, G., Van der Schueren, B., & Vandamme, K. (2020). Alteration of the Condylar Oral Bone in Obese and Gastric Bypass Mice. Calcified Tissue International, 107(4), 371-380. https://doi.org/10.1007/s00223-020-00732-0 (Original work published 2020)
Journal article
Beekman, K. M., Zwaagstra, M., Veldhuis-Vlug, A. G., van Essen, H. W., den Heijer, M., Maas, M., Kerckhofs, G., Parac-Vogt, T. N., Bisschop, P. H., & Bravenboer, N. (2019). Ovariectomy increases RANKL protein expression in bone marrow adipocytes of C3H/HeJ mice. American Journal of Physiology-Endocrinology and Metabolism, 317(6), E1050-E1054. https://doi.org/10.1152/ajpendo.00142.2019 (Original work published 2019)
Penel, G., Kerckhofs, G., & Chauveau, C. (2019). Brief Report From the 4th International Meeting on Bone Marrow Adiposity (BMA2018). Frontiers in Endocrinology, 10. https://doi.org/10.3389/fendo.2019.00691 (Original work published 2019)
Zhao, L., Ding, L., Soete, J., Idrissi, H., Kerckhofs, G., & Simar, A. (2019). Fostering crack deviation via local internal stresses in Al/NiTi composites and its correlation with fracture toughness. Composites Part A: Applied Science and Manufacturing, 126, 105617. https://doi.org/10.1016/j.compositesa.2019.105617 (Original work published 2019)
de Bournonville, S., Vangrunderbeeck, S., & Kerckhofs, G. (2019). Contrast-Enhanced MicroCT for Virtual 3D Anatomical Pathology of Biological Tissues: A Literature Review. Contrast Media & Molecular Imaging, 2019, 1-9. https://doi.org/10.1155/2019/8617406 (Original work published 2019)
De Clercq, K., Persoons, E., Napso, T., Luyten, C., Parac-Vogt, T. N., Sferruzzi-Perri, A. N., Kerckhofs, G., & Vriens, J. (2019). High-resolution contrast-enhanced microCT reveals the true three-dimensional morphology of the murine placenta. Proceedings of the National Academy of Sciences, 201902688. https://doi.org/10.1073/pnas.1902688116 (Original work published 2019)
Coutel, X., Delattre, J., Marchandise, P., Falgayrac, G., Béhal, H., Kerckhofs, G., Penel, G., & Olejnik, C. (2019). Mandibular bone is protected against microarchitectural alterations and bone marrow adipose conversion in ovariectomized rats. Bone, 127, 343-352. https://doi.org/10.1016/j.bone.2019.06.031 (Original work published 2019)
Bolette, A., Lecloux, G., Rompen, E., Albert, A., Kerckhofs, G., & Lambert, F. (2019). Influence of induced infection in medication-related osteonecrosis of the jaw development after tooth extraction: a study in rats. Journal of Cranio-Maxillofacial Surgery, 47(2), 349-356. https://doi.org/10.1016/j.jcms.2018.08.011 (Original work published 2019)
Journal article
Ji, W., Kerckhofs, G., Geeroms, C., Marechal, M., Geris, L., & Luyten, F. P. (2018). Deciphering the combined effect of bone morphogenetic protein 6 and calcium phosphate on bone formation capacity of periosteum derived cells-based tissue engineering constructs. Acta Biomaterialia, 80, 97-107. https://doi.org/10.1016/j.actbio.2018.09.046 (Original work published 2018)
Cao, W., Sun, T., Kerckhofs, G., Fardell, G., Price, B., & Dewulf, W. (2018). A simulation-based study on the influence of the x-ray spectrum on the performance of multi-material beam hardening correction algorithms. Measurement Science and Technology, 29(9), 95002. https://doi.org/10.1088/1361-6501/aacba0 (Original work published 2018)
Beekman, K. M., Veldhuis-Vlug, A. G., van der Veen, A., den Heijer, M., Maas, M., Kerckhofs, G., Parac-Vogt, T. N., Bisschop, P. H., & Bravenboer, N. (2018). The effect of PPARγ inhibition on bone marrow adipose tissue and bone in C3H/HeJ mice. American Journal of Physiology-Endocrinology and Metabolism, 316(1), E96-E105. https://doi.org/10.1152/ajpendo.00265.2018 (Original work published 2019)
Marin, C., Luyten, F., Van Der Schueren, B., Kerckhofs, G., & Vandamme, K. (2018). The impact of type 2 diabetes on bone fracture healing. Frontiers in Endocrinology, 9(6). https://doi.org/10.3389/fendo.2018.00006 (Original work published 2018)
Marin, C., Papantonakis, G., Sels, K., van Lenthe, G. H., Falgayrac, G., Vangoitsenhoven, R., Van der Schueren, B., Penel, G., Luyten, F., Vandamme, K., & Kerckhofs, G. (2018). Unraveling the compromised biomechanical performance of type 2 diabetes- and Roux-en-Y gastric bypass bone by linking mechanical-structural and physico-chemical properties. Scientific Reports, 8(1), 5881. https://doi.org/10.1038/s41598-018-24229-x (Original work published 2018)
Kerckhofs, G., Stegen, S., van Gastel, N., Sap, A., Falgayrac, G., Penel, G., Durand, M., Luyten, F., Geris, L., Vandamme, K., Parac-Vogt, T., & Carmeliet, G. (2018). Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure. Biomaterials, 159, 1-12. https://doi.org/10.1016/j.biomaterials.2017.12.016 (Original work published 2018)
Coutel, X., Olejnik, C., Marchandise, P., Delattre, J., Béhal, H., Kerckhofs, G., & Penel, G. (2018). A Novel microCT Method for Bone and Marrow Adipose Tissue Alignment Identifies Key Differences Between Mandible and Tibia in Rats. Calcified Tissue International, 103(2), 189-197. https://doi.org/10.1007/s00223-018-0397-1 (Original work published 2018)
Book chapter
Wevers, M., Nicolai, B., Verboven, P., Swennen, R., Roels, S., Verstrynge, E., Lomov, S. V., Kerckhofs, G., Van Meerbeek, B., Mavridou, A., Bergmans, L., Lambrechts, P., Soete, J., Claes, S., & Claes, H. (2018). Applications of CT for non-destructive testing and materials characterization. In Carmignato, Simone ; Dewulf, Wim ; Leach, Richard (ed.), Industrial X-Ray Computed Tomography (p. p. 267-331). Springer. https://hdl.handle.net/2078.5/236575
Journal article
Guns, L.-A., Monteagudo, S., Kvasnytsia, M., Kerckhofs, G., Vandooren, J., Opdenakker, G., Lories, R., & Cailotto, F. (2017). Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo. R M D Open, 3(2), e000604. https://doi.org/10.1136/rmdopen-2017-000604 (Original work published 2017)
Manhas, V., Guyot, Y., Kerckhofs, G., Chai, Y. C., & Geris, L. (2017). Computational modelling of local calcium ions release from calcium phosphate-based scaffolds. Biomechanics and Modeling in Mechanobiology, 16(2), 425-438. https://doi.org/10.1007/s10237-016-0827-9 (Original work published 2017)
Journal article
Kerckhofs, G., Durand, M., Vangoitsenhoven, R., Marin, C., Van Der Schueren, B., Carmeliet, G., Luyten, F., Geris, L., & Vandamme, K. (2016). Changes in bone macro- and microstructure in diabetic obese mice revealed by high resolution microfocus X-ray computed tomography. Scientific Reports, 6(35517). https://doi.org/10.1038/srep35517 (Original work published 2016)
Mavridou, A., Pyka, G., Kerckhofs, G., Wevers, M., Bergmans, L., Gunst, V., Huybrechts, B., Schepers, E., Hauben, E., & Lambrechts, P. (2016). A novel multimodular methodology to investigate external cervical tooth resorption. International Endodontic Journal, 49(3), 287-300. https://doi.org/10.1111/iej.12450 (Original work published 2016)
Kerckhofs, G., Chai, Y. C., Luyten, F. P., & Geris, L. (2016). Combining microCT-based characterization with empirical modelling as a robust screening approach for the design of optimized CaP-containing scaffolds for progenitor cell-mediated bone formation. Acta Biomaterialia, 35, 330-340. https://doi.org/10.1016/j.actbio.2016.02.037 (Original work published 2016)
Journal article
Sonnaert, M., Kerckhofs, G., Papantoniou, I., Van Vlierberghe, S., Boterberg, V., Dubruel, P., Luyten, F., Schrooten, J., & Geris, L. (2015). Multifactorial Optimization of Contrast-Enhanced Nanofocus Computed Tomography for Quantitative Analysis of Neo-Tissue Formation in Tissue Engineering Constructs. PLoS One, 10(6), 1-17. https://doi.org/10.1371/journal.pone.0130227 (Original work published 2015)
Journal article
Kerckhofs, G., Sainz, J., Marechal, M., Wevers, M., Van de Putte, T., Geris, L., & Schrooten, J. (2014). Contrast-enhanced nanofocus X-ray computed tomography allows virtual three-dimensional histopathology and morphometric analysis of osteoarthritis in small animal models. Cartilage, 5(1), 55-65. https://doi.org/10.1177/1947603513501175 (Original work published 2014)
Papantoniou, I., Guyot, Y., Sonnaert, M., Kerckhofs, G., Luyten, F., Geris, L., & Schrooten, J. (2014). Spatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes. Biotechnology and Bioengineering, 111(12), 2560-2570. https://doi.org/10.1002/bit.25303 (Original work published 2014)
Papantoniou, I., Sonnaert, M., Geris, L., Luyten, F., Schrooten, J., & Kerckhofs, G. (2014). Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography. Tissue Engineering. Part C. Methods, 20(3), 177-187. https://hdl.handle.net/2078.5/236622 (Original work published 2014)
Lambrechts, D., Roeffaers, M., Kerckhofs, G., Hofkens, J., Van de Putte, t., Schrooten, J., & Van Oosterwyck, H. (2014). Reporter cell activity within hydrogel constructs quantified from oxygen-independent bioluminescence. Biomaterials, 35(28), 8065-8077. https://doi.org/10.1016/j.biomaterials.2014.06.002 (Original work published 2014)
Pyka, G. *., Kerckhofs, G., Schrooten, J., & Wevers, M. (2014). The effect of spatial micro-CT image resolution and surface complexity on the morphological 3D analysis of open porous structures. Materials Characterization, 87, 104-115. https://hdl.handle.net/2078.5/90831 (Original work published 2014)
Pyka, G., Kerckhofs, G., Schrooten, J., & Wevers, M. (2014). The effect of spatial micro-CT image resolution and surface complexity on the morphological 3D analysis of open porous structures. Materials Characterization, 87, 104-115. https://doi.org/10.1016/j.matchar.2013.11.004 (Original work published 2014)
Sonnaert, M., Papantoniou, I., Bloemen, V., Kerckhofs, G., Luyten, F., & Schrooten, J. (2014). Human periosteal-derived cell expansion in a perfusion bioreactor system: proliferation, differentiation and extracellular matrix formation. Journal of Tissue Engineering and Regenerative Medicine, 11(2), 519-530. https://doi.org/10.1002/term.1951 (Original work published 2014)
Journal article
Pyka, G., Kerckhofs, G., Papantoniou, I., Speirs, M., Schrooten, J., & Wevers, M. (2013). Surface roughness and morphology customization of additive manufactured open porous Ti6Al4V structures. Materials, 6, 4737-4757. https://doi.org/10.3390/ma6104737 (Original work published 2013)
Karunratanakul, K., Kerckhofs, G., Lammens, J., Vanlauwe, J., Schrooten, J., & Van Oosterwyck, H. (2013). Validation of a finite element model of a unilateral external fixator in a rabbit tibia defect model. Medical Engineering & Physics, 35(7), 1037-1043. https://doi.org/10.1016/j.medengphy.2012.10.006 (Original work published 2013)
Kerckhofs, G., Sainz, J., Wevers, M., Van de Putte, T., & Schrooten, J. (2013). Contrast-enhanced nanofocus computed tomography images the cartilage subtissue architecture in three dimensions. European Cells & Materials, 25, 179-189. https://hdl.handle.net/2078.5/236641 (Original work published 2013)
Lambrechts, D., Roeffaers, M., Kerckhofs, G., Roberts, S., Hofkens, J., Van de Putte, T., Van Oosterwyck, H., & Schrooten, J. (2013). Fluorescent oxygen sensitive microbead incorporation for measuring oxygen tension in cell aggregates. Biomaterials, 34(4), 922-929. https://hdl.handle.net/2078.5/236627 (Original work published 2013)
Kerckhofs, G., Pyka, G., Moesen, M., Van Bael, S., Schrooten, J., & Wevers, M. (2013). High-resolution microfocus X-ray computed tomography for 3D surface roughness measurements of additive manufactured porous materials. Advanced Engineering Materials, 15(3), 153-158. https://doi.org/10.1002/adem.201200156 (Original work published 2013)
Journal article
Van Bael, S., Chai, Y. C., Truscello, S., Moesen, M., Kerckhofs, G., Van Oosterwyck, H., Kruth, J.-P., & Schrooten, J. (2012). The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser melted Ti6Al4V bone scaffolds. Acta Biomaterialia, 8(7), 2824-2834. https://doi.org/10.1016/j.actbio.2012.04.001 (Original work published 2012)
Chai, Y. C., Roberts, S. J., Desmet, E., Kerckhofs, G., van Gastel, N., Geris, L., Carmeliet, G., Schrooten, J., & Luyten, F. (2012). Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers. Biomaterials, 33(11), 3127-3142. https://doi.org/10.1016/j.biomaterials.2012.01.015 (Original work published 2012)
Chai, Y. C., Kerckhofs, G., Roberts, S., Van Bael, S., Schepers, E., Vleugels, J., Luyten, F., & Schrooten, J. (2012). Ectopic bone formation by 3D porous calcium phosphate-Ti6Al4V hybrids produced by perfusion electrodeposition. Biomaterials, 33(16), 4044-4058. https://hdl.handle.net/2078.5/236652 (Original work published 2012)
Pfeiffer, H., Heer, P., Pitropakis, I., Pyka, G., Kerckhofs, G., Patitsa, M., & Wevers, M. (2012). Liquid detection in confined aircraft structures based on lyotropic percolation thresholds. Sensors and Actuators B: Chemical : international journal devoted to research and development of physical and chemical transducers, 161(1), 791-798. https://hdl.handle.net/2078.5/236653 (Original work published 2012)
Truscello, S., Kerckhofs, G., Van Bael, S., Pyka, G., Schrooten, J., & Van Oosterwyck, H. (2012). Prediction of permeability of regular scaffolds for skeletal tissue engineering: A combined computational and experimental study. Acta Biomaterialia, 8(4), 1648-1658. https://doi.org/10.1016/j.actbio.2011.12.021 (Original work published 2012)
Alam, K., Kerckhofs, G., Mitrofanov, A., Lomov, S. V., Wevers, M., & Silberschmidt, V. V. (2012). On-line analysis of cracking in cortical bone under wedge penetration. Institution of Mechanical Engineers. Proceedings. Part H: Journal of Engineering in Medicine, 226(H9), 709-717. https://hdl.handle.net/2078.5/236655 (Original work published 2012)
Pyka, G., Burakowski, A., Kerckhofs, G., Moesen, M., Van Bael, S., Schrooten, J., & Wevers, M. (2012). Surface modification of Ti6Al4V open porous structures produced by additive manufacturing. Advanced Engineering Materials, 14(6), 363-370. https://doi.org/10.1002/adem.201100344 (Original work published 2012)
Journal article
Roberts, S., Geris, L., Kerckhofs, G., Desmet, E., Schrooten, J., & Luyten, F. (2011). The combined bone forming capacity of human periosteal derived cells and calcium phosphates. Biomaterials, 32(19), 4393-4405. https://hdl.handle.net/2078.5/236663 (Original work published 2011)
Van Bael, S., Kerckhofs, G., Moesen, M., Pyka, G., Schrooten, J., & Kruth, J.-P. (2011). Micro-CT-based improvement of geometrical and mechanical controllability of selective laser melted Ti6Al4V porous structures. Materials Science and Engineering A, Structural Materials: Properties, Microstructure and Processing, 528(24), 7423-7431. https://hdl.handle.net/2078.5/236667 (Original work published 2011)
Book chapter
Verboven, P., Ho, Q., Herremans, E., Mebatsion, H., Nicolai, B., Kerckhofs, G., Wevers, M., & Cloetens, P. (2011). Fruit Microstructure Evaluation Using Synchrotron X-Ray Computed Tomography. In Aguilera J., Barbosa-Canovas G., Simpson R., Welti-Chanes J., Berludez-Aguirre D. (Eds.) (ed.), Food Engineering Interfaces (p. p. Chapter 24). Springer. https://hdl.handle.net/2078.5/236666
Journal article
Mendoza, F., Verboven, P., Tri Ho, Q., Kerckhofs, G., Wevers, M., & Nicolai, B. (2010). Multifractal properties of pore-size distribution in apple tissue using X-ray imaging. Journal of Food Engineering, 99, 206-215. https://hdl.handle.net/2078.5/236690 (Original work published 2010)
Neirinck, B., Kerckhofs, G., Wevers, M., Van der Biest, O., & Vleugels, J. (2010). Morphological analysis of slip-cast emulsion-templated alumina foams by microfocus computer tomography. Journal of the American Ceramic Society, 93(11), 3921-3928. https://hdl.handle.net/2078.5/236682 (Original work published 2010)
Wilderjans, E., Kerckhofs, G., Lagrain, B., Brijs, K., Wevers, M., & Delcour, J. (2010). Baking gradients cause heterogeneity in starch and proteins in pound cake. Cereal Chemistry, 87(5), 475-480. https://hdl.handle.net/2078.5/174598 (Original work published 2010)
Journal article
Pareyt, B., Talhaoui, F., Kerckhofs, G., Brijs, K., Goesaert, H., Wevers, M., & Delcour, J. (2009). The role of sugar and fat in sugar-snap cookies: Structural and textural properties. Journal of Food Engineering, 90(3), 400-408. https://doi.org/10.1016/j.jfoodeng.2008.07.010 (Original work published 2009)
Journal article
Verboven, P., Kerckhofs, G., Mebatsion, H., Ho, Q. T., Temst, K., Wevers, M., Cloetens, P., & Nicolai, B. (2008). Three-dimensional gas exchange pathways in pome fruit characterized by synchrotron X-ray computed tomography. Plant Physiology, 147(2), 518-527. https://hdl.handle.net/2078.5/236714 (Original work published 2008)
Kerckhofs, G., Schrooten, J., Van Cleynenbreugel, T., Lomov, S. V., & Wevers, M. (2008). Validation of x-ray microfocus computed tomography as an imaging tool for porous structures. Review of scientific instruments, 79(1), 013711-013711. https://hdl.handle.net/2078.5/236707 (Original work published 2008)
Léonard, A., Calberg, C., Kerckhofs, G., Wevers, M., Jérôme, R., Pirard, J.-P., Germain, A., & Blacher, S. (2008). Characterization of the porous structure of biodegradable scaffolds obtained with supercritical CO2 as foaming agent. Journal of Porous Materials, 15(4), 397-403. https://hdl.handle.net/2078.5/236711 (Original work published 2008)
Journal article
Mendoza, F., Verboven, P., Mebatsion, H. K., Kerckhofs, G., Wevers, M., & Nicolai, B. (2007). Three-dimensional pore space quantification of apple tissue using X-ray computed microtomography. Planta : an international journal of plant biology, 226(3), 559-570. https://hdl.handle.net/2078.5/236719 (Original work published 2007)
Journal article
Blacher, S., Calberg, C., Kerckhofs, G., Leonard, A., Wevers, M., Jerôme, R., & Rirard, J.-P. (2006). The porous structure of biodegradable scaffolds obtained with supercritical CO2 as foaming agent. Studies in Surface Science and Catalysis, 160, 681-688. https://hdl.handle.net/2078.5/174669 (Original work published 2006)
