Randy BUZISA MBUKU - Thesis public defence

Randy BUZISA MBUKU – TFAR FACM/NMSK (IREC)

Therapeutic innovation in PJI: A biofilm-disrupting and drug-delivering hydrogel incorporating an enzymatic cocktail

Promotor: Prof. Olivier Cornu
Co-promotor: Prof. Françoise Van Bambeke

Related publications :
•    Buzisa Mbuku, R, Poilvache H, Maigret L, Vanbever R, Van Bambeke F, Cornu O. Targeting Staphylococcus aureus biofilm-related infections on implanted material with a novel dual-action thermosensitive hydrogel containing vancomycin and a tri-enzymatic cocktail: in vitro and in vivo studies. Biofilm 2025;9:100288. DOI: https://doi.org/10.1016/j.bioflm.2025.100288.
•    Buzisa Mbuku, R, Poilvache H, Maigret L, Vanbever R, Van Bambeke F, Cornu O. Enzymes-enhanced antibiotic therapy reduces biofilms to undetectable levels in an implant-associated infection model. (npj biofilms and microbiomes doi : 10.1038/s41522-026-00910-2)

This thesis defence took place on January 13, 2026.