Chi-Hsien LEE - Thesis public defense

Chi-Hsien LEE – MNUT  

Discovery of a novel myo-inositol to butyrate fermentation pathway and taxonomic expansion of the genus Dysosmobacter in the human gut

Promotor: Prof. Patrice Cani

Related publications:
•    Lee C-H, Bui TPN, Petitfils C, Jian C, Wong GC, Puel A, Le Roy T, Bellais S, Ben Abdallah B, Nehlich M, Leicht T, Jia M, Hoyles L, Federici M, Fernández-Real JM, Burcelin R, Dumas M-E, Delzenne NM, Clavel T, Boeren S, Troise AD, Scaloni A, Muccioli GG, de Vos WM, Van Hul M, Cani PD. Novel myo-inositol to butyrate fermentation pathway in the prevalent human gut species Dysosmobacter welbionis, a bacterium associated with improved metabolic and liver health. Gut. 2026; doi:10.1136/gutjnl-2025-336617.
•    Lee C-H, Petitfils C, Bui TPN, Van Der Smissen P, Delzenne NM, Tyteca D, de Vos WM, Van Hul M, Cani PD. Dysosmobacter phytatis sp. nov., isolated from human feces, with Oscillibacter acetigenes as a later heterotypic synonym of Dysosmobacter welbionis and Pusillibacter faecalis as a later heterotypic synonym of Dysosmobacter hominis. Submitted to IJSEM in 2026. 

This thesis defense took place on April 22, 2026.