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Publications

ldri | Bruxelles Woluwe

PREAT Véronique

  1. Bausart M, Vanvarenberg K, Ucakar B, Lopes A, Vandermeulen G, Malfanti A, Préat V. Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model, Pharmaceutics (2022) 14 1025
  2. Malfanti A, Catania G, Degros Q, Wang M, Bausart M, Préat V.
    Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma, Pharmaceutics (2022) 14 124.
  3. Bausart M, Préat V, Malfanti A, Immunotherapy for glioblastoma: the promise of combination strategies, J Exp Clin Cancer Res (2022) 41 35.
  4. Lopes A, Bastiancich C, Bausart M, Ligot S, Lambricht L, Vanvarenberg K, Ucakar B, Gallez B, Préat V, Vandermeulen G. New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models, J Immunother (2021) 9 e001243
  5. Bastiancich C, Malfanti A, Préat V, Rahman R. Rationally designed drug delivery systems for the local treatment of resected glioblastoma, Adv Drug Deliv Rev (2021) 113951.
     

VANBEVER Rita

  1. Rondon A, Mahri S., Morales-Yanez F., Dumoulin M., Vanbever R.
    Protein engineering strategies for improved pharmacokinetics,
    Adv Funct Mater (2021) 2101633.
  2. Loira-Pastoriza C., Vanvarenberg K., Ucakar B, Machado Franco M, Staub A, Lemaire M, Renauld J C, Vanbever R.
    Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer.
    Int J Pharm (2021) 600: 120504.
  3. Mahri S, Rondon A, Wilms T, Bosquillon C, Vanbever R.
    Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.
    J Control Release (2021), 329: 1054-1065.
  4. Guichard M-J, Wilms T, Mahri S, Patil H P, Hoton D, Ucakar B, Vanvarenberg K, Cheou P, Beka M, Marbaix E Leal T, Vanbever R.
    PEGylation of recombinant human deoxyribonuclease I provides a long-acting version of the mucolytic for patients with cystic fribrosis.
    Adv Ther (2021) 2000146 (1-17)
  5. Patil H P, Freches D, Karmani L, Duncan G, Ucakar B, Suk J S, Hanes J, Gallez B, Vanbever R.
    Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation.
    J Control Release (2018) 272: 62-71.
     

LELOUP Gaetane - LEPRINCE Julian

  1. Leprince JG, Van Nieuwenhuysen J.-P.
    The missed root canal story: aren’t we missing the point? Int Endod J. 2020 53, 1162–1166.
  2. Leroy R, Bourgeois J, Verleye L, Declerck D, Depuydt P, Eloot A, Carvalho JC, Teughels W, Cauwels R, Leprince J, Toma S, Michiels K, Aryanpour S, Vanden Abbeele A, De Bruyne M.
    Guideline on the prudent prescription of antibiotics in the dental office – Supplement. Good Clinical Practice (GCP) Brussels: Belgian Health Care Knowledge Centre (KCE).
    2020. KCE Reports 332S. D/2020/10.273/24.
  3. Hardy CMF, Bebelman S, Leloup G, Hadis MA, Palin WM, Leprince JG.
    Investigating the limits of resin-based luting composite photopolymerization through various thicknesses of indirect restorative materials.
    Dent Mater. 2018 May 29. pii: S0109-5641(17)31368-4. doi: 10.1016/j.dental.2018.05.009.
  4. Randolph L D, Palin W M, Bebelman S, Devaux J, Gallez B, Leloup G, Leprince J G.
    Photopolymerization of highly filled dimethacrylate-based composites using Type I or Type II photoinitiators and varying co-monomer ratios.
    Dent Mater. (2016) 32: 136-48.
  5. Randolph LD, Palin WM, Leloup G, Leprince J G.
    Filler characteristics of modern dental resin composites and their influence on physico-mechanical properties.
    Dent Mater. (2016) 32:1586-1599.
  6. Leprince J G, Palin W M, Hadis M A, Devaux J, Leloup G.
    Progress in dimethacrylate-based dental composite technology and curing efficiency.
    Dent Mater. (2013) 29: 139-156.


DES RIEUX Anne

  1. Gratpain, V., A. Mwema, Y. Labrak, G. G. Muccioli, V. van Pesch and A. des Rieux (2021).
    Extracellular vesicles for the treatment of central nervous system diseases."
    Adv Drug Deliv Rev 174: 535-552.
  2. Carradori, D., Y. Labrak, V. E. Miron, P. Saulnier, J. Eyer, V. Preat and A. des Rieux (2020).
    Retinoic acid-loaded NFL-lipid nanocapsules promote oligodendrogenesis in focal white matter lesion.
    Biomaterials 230: 119653.
  3. Kandalam, S., P. De Berdt, B. Ucakar, K. Vanvarenberg, C. Bouzin, V. Gratpain, A. Diogenes, C. N. Montero-Menei and A. des Rieux (2020).
    Human dental stem cells of the apical papilla associated to BDNF-loaded pharmacologically active microcarriers (PAMs) enhance locomotor function after spinal cord injury.
    Int J Pharm 587: 119685.
  4. Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A.
    A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.
    Nat Protoc (2017) 12:1387-1399.
  5. De Berdt P, Vanacker J, Ucakar B, Elens L, Diogenes A, Leprince JG, Deumens R, des Rieux A.
    Dental Apical Papilla as Therapy for Spinal Cord Injury.
    J Dent Res (2015) 94:1575-1581.


BELOQUI Ana

  1. Xu Y, van Hul M, Suriano F, Préat V, Cani PD, Beloqui A.
    Novel strategy for oral peptide delivery in incretin-based diabetes treatment.
    Gut (2020) 69:911-919.
  2. Xu Y, De Keersmaecker H, Braeckmans K, De Smedt S, Cani PD, Préat V, Beloqui A.
    Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment.
    Biomaterials (2020) 120209.
  3. Shrestha N, Bouttefeux O, Vanvarenberg K, Lunquist P, Cunarro J, Tovar S, Khodus G, Andersson E, Keita ÅV, González Dieguez C, Artursson P, Préat V, Beloqui A.
    The stimulation of GLP-1 secretion and delivery of GLP-1 agonists via nanostructured lipid carriers.
    Nanoscale (2018) 10:603-613
  4. Beloqui A, des Rieux A, Préat V.
    Mechanisms of transport of polymeric and lepidic nanoparticles across the intestinal barrier.
    Adv Drug Deliv Rev. (2016) 106:242-255.
  5. Beloqui A, Solinís MA, Gascón AR, del Pozo-Rodríguez A, des Rieux A, Préat V.
    Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier,
    J Control Release (2013) 166:115-123.

Ana Beloqui

  • 2026
    • Article de journal
      Chen, C., Guilbaud, L., Marotti, V., Zhang, W., Ladeiro Domingues, I., Yagoubi, H., Vints, K., Xu, Y., & Beloqui Garcia, A. (2026). An antioxidant metal-organic framework with functional coatings for oral anti-TNF-α antibody delivery in inflammatory bowel disease treatment. Journal of Controlled Release, 389, 114411. https://doi.org/10.1016/j.jconrel.2025.114411 (Original work published 2026)
  • 2025
    • Article de journal
      Xu, Y., Drucker, D. J., Traverso, G., & Beloqui Garcia, A. (2025). Innovative molecules and delivery technologies enabling the future of GLP-1-based therapies. Endocrine Reviews, bnaf027. https://doi.org/10.1210/endrev/bnaf027 (Original work published 2025)
    • Zhang, W., Van den Bossche, W., Yagoubi, H., Kambale Kavungere, E., Whani, K., Saxena, T., Guilbaud, L., Moreels, T., Messens, J., & Beloqui Garcia, A. (2025). Glepaglutide-loaded foam for the induction of mucosal healing in the treatment of inflammatory bowel disease. Advanced Healthcare Materials. Accepted/in-press. (Original work published 2025)
    • Guilbaud, L., Chen, C., Ladeiro Domingues, I., Kambale Kavungere, E., Marotti, V., Yagoubi, H., Zhang, W., Malfanti, A., & Beloqui Garcia, A. (2025). Oral Lipid-Based Nanomedicine for the Inhibition of the cGAS-STING Pathway in Inflammatory Bowel Disease Treatment. Molecular Pharmaceutics, 22(4), 2108-2121. https://doi.org/10.1021/acs.molpharmaceut.4c01297 (Original work published 2025)
    • Wang, Y., Chen, C., Xiao, X., Kang, Y., He, J., Beloqui Garcia, A., & Xu, Y. (2025). Advanced oral therapies for colorectal cancer via nanomedicine and microbiota modulation. Advanced Drug Delivery Reviews, 115741. https://doi.org/10.1016/j.addr.2025.115741 (Original work published 2025)
  • 2024
    • Article de journal
      Xu, Y., Bohns Michalowski, C., Koehler, J., Darwish, T., Guccio, N., Alcaino, C., Ladeiro Domingues, I., Zhang, W., Marotti, V., Van Hul, M., Paone, P., Koutsoviti, M., Boyd, B. J., Drucker, D. J., Cani, P., Reimann, F., Gribble, F. M., & Beloqui Garcia, A. (2024). Smart control lipid-based nanocarriers for fine-tuning gut hormone secretion. Science advances, 10(50), eadq9909 [1-18]. https://doi.org/10.1126/sciadv.adq9909 (Original work published 2024)
    • Beloqui Garcia, A., Ling, D., & Manickam, D. S. (2024). Editorial – JCR EBM SI. Journal of Controlled Release, 365, 801. https://doi.org/10.1016/j.jconrel.2023.11.059 (Original work published 2024)
    • Ladeiro Domingues, I., Yagoubi, H., Zhang, W., Marotti, V., Kambale Kavungere, E., Vints, K., Sliwinska, M. A., Leclercq, I., & Beloqui Garcia, A. (2024). Effects of semaglutide-loaded lipid nanocapsules on metabolic dysfunction-associated steatotic liver disease. Drug Delivery and Translational Research, 14(10), 2917-2929. https://doi.org/10.1007/s13346-024-01576-z (Original work published 2024)
    • Beloqui Garcia, A. (2024). Gut hormone stimulation as a therapeutic approach in oral peptide delivery. Journal of Controlled Release, 373, 31-37. https://doi.org/10.1016/j.jconrel.2024.07.007 (Original work published 2024)
    • Marotti, V., Xu, Y., Bohns Michalowski, C., Zhang, W., Ladeiro Domingues, I., Ameraoui, H., Moreels, T., Baatsen, P., Van Hul, M., Muccioli, G., Cani, P., Al Houayek, M., Malfanti, A., & Beloqui Garcia, A. (2024). A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment. Bioactive materials, 32, 206-221. https://doi.org/10.1016/j.bioactmat.2023.09.014 (Original work published 2024)
    • Kambale Kavungere, E., Ladeiro Domingues, I., Zhang, W., Marotti, V., Chen, C., Hughes, K., Leclercq, J., Memvanga, P. B., & Beloqui Garcia, A. (2024). “Green” synthesized versus chemically synthesized zinc oxide nanoparticles: In vivo antihyperglycemic activity and pharmacokinetics. International Journal of Pharmaceutics, 650, 123701 [1-8]. https://doi.org/10.1016/j.ijpharm.2023.123701 (Original work published 2024)
    • Feig, V. R., Zhang, S., Patel, A., Santos, B., Kang, Z., Wasan, S., Beloqui Garcia, A., & Traverso, G. (2024). Designing for medication adherence in inflammatory bowel disease: multi-disciplinary approaches for self-administrable biotherapeutics. EClinicalMedicine, 77, 102850 [1-14]. https://doi.org/10.1016/j.eclinm.2024.102850 (Original work published 2024)
    • Zhang, W., McCartney, F., Xu, Y., Michalowski, C. B., Ladeiro Domingues, I., Kambale Kavungere, E., Moreels, T., Guilbaud, L., Chen, C., Marotti, V., Brayden, D. J., & Beloqui Garcia, A. (2024). An in situ bioadhesive foam as a large intestinal delivery platform for antibody fragment to treat inflammatory bowel disease. Journal of Controlled Release, 374, 254-266. https://doi.org/10.1016/j.jconrel.2024.08.023 (Original work published 2024)
    • Moens de Hase, E., Neyrinck, A., Rodriguez, J., Cnop, M., Paquot, N., Thissen, J.-P., Xu, Y., Beloqui Garcia, A., Bindels, L., Delzenne, N., Van Hul, M., & Cani, P. (2024). Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention. Diabetologia : clinical and experimental diabetes and metabolism, 67(2), 333-345. https://doi.org/10.1007/s00125-023-06032-0 (Original work published 2024)
  • 2023
    • Article de journal
      Ladeiro Domingues, I., Leclercq, I., & Beloqui Garcia, A. (2023). Nonalcoholic fatty liver disease: Current therapies and future perspectives in drug delivery. Journal of Controlled Release, 363, 415-434. https://doi.org/10.1016/j.jconrel.2023.09.040 (Original work published 2023)
    • Chen, C., Beloqui Garcia, A., & Xu, Y. (2023). Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease. Advanced Drug Delivery Reviews, 203, 115117. https://doi.org/10.1016/j.addr.2023.115117 (Original work published 2023)
    • Pinto, E. P., da Costa, S. O. A. M., D’Haese, C., Nysten, B., Machado, F. P., Rocha, L. M., de Souza, T. M., Beloqui Garcia, A., Machado, R. R., & Araújo, R. S. (2023). Poly-ɛ-caprolactone nanocapsules loaded with copaiba essential oil reduce inflammation and pain in mice. International Journal of Pharmaceutics, 642(1), 123147 [1-10]. https://doi.org/10.1016/j.ijpharm.2023.123147 (Original work published 2023)
    • Ladeiro Domingues, I., Bohns Michalowski, C., Marotti, V., Zhang, W., Van Hul, M., Cani, P., Leclercq, I., & Beloqui Garcia, A. (2023). Exploiting the biological effect exerted by lipid nanocapsules in non-alcoholic fatty liver disease. Journal of Controlled Release, 356, 542-553. https://doi.org/10.1016/j.jconrel.2023.03.012 (Original work published 2023)
    • Kambale Kavungere, E., Katemo, F. M., Leclercq, J., Memvanga, P. B., & Beloqui Garcia, A. (2023). “Green”-synthesized zinc oxide nanoparticles and plant extracts: A comparison between synthesis processes and antihyperglycemic activity. International Journal of Pharmaceutics, 635, 122715 [1-8]. https://doi.org/10.1016/j.ijpharm.2023.122715 (Original work published 2023)
  • 2022
    • Article de journal
      Lundquist, P., Khodus, G., Niu, Z., Thwala, L. N., McCartney, F., Simoff, I., Andersson, E., Beloqui Garcia, A., Mabondzo, A., Robla, S., Webb, D.-L., Hellström, P. M., Keita, Å. V., Sima, E., Csaba, N., Sundbom, M., Préat, V., Brayden, D. J., Alonso, M. J., & Artursson, P. (2022). Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat. ACS Nano, 16(9), 14210-14229. https://doi.org/10.1021/acsnano.2c04330 (Original work published 2022)
    • Kambale Kavungere, E., Leclercq, J., Memvanga, P. B., & Beloqui Garcia, A. (2022). An Overview of Herbal-Based Antidiabetic Drug Delivery Systems: Focus on Lipid- and Inorganic-Based Nanoformulations. Pharmaceutics, 14(10), 2135 [1-42]. https://doi.org/10.3390/pharmaceutics14102135 (Original work published 2022)
    • Xu, Y., Fourniols, T., Labrak, Y., Préat, V., Beloqui Garcia, A., & des Rieux, A. (2022). Surface Modification of Lipid-Based Nanoparticles. ACS Nano, 16, 7168-7196. https://doi.org/10.1021/acsnano.2c02347 (Original work published 2022)
    • Shrestha, N., Xu, Y., Prévost, J. R. C., McCartney, F., Brayden, D., Frédérick, R., Beloqui Garcia, A., & Préat, V. (2022). Impact of PEGylation on an antibody-loaded nanoparticle-based drug delivery system for the treatment of inflammatory bowel disease. Acta Biomaterialia, 140, 561-572. https://doi.org/10.1016/j.actbio.2021.12.015 (Original work published 2022)
    • Gonzalez-Pujana, A., Beloqui Garcia, A., Javier Aguirre, J., Igartua, M., Santos-Vizcaino, E., & Maria Hernandez, R. (2022). Mesenchymal stromal cells encapsulated in licensing hydrogels exert delocalized systemic protection against ulcerative colitis via subcutaneous xenotransplantation. European Journal of Pharmaceutics and Biopharmaceutics, 172, 31-40. https://doi.org/10.1016/j.ejpb.2022.01.007 (Original work published 2022)
  • 2021
    • Article de journal
      Xu, Y., Bohns-Michalowski, C., & Beloqui Garcia, A. (2021). Advances in lipid carriers for drug delivery to the gastrointestinal tract. Current Opinion in Colloid & Interface Science, 52, 101414 [1-17]. https://doi.org/10.1016/j.cocis.2020.101414 (Original work published 2020)
    • Zhang, W., Bohns Michalowski, C., & Beloqui Garcia, A. (2021). Oral Delivery of Biologics in Inflammatory Bowel Disease Treatment. Frontiers in Bioengineering and Biotechnology, 9. https://doi.org/10.3389/fbioe.2021.675194 (Original work published 2021)
    • Buya, A., Terrasi, R., Mbinze, J. K., Muccioli, G., Beloqui Garcia, A., Memvanga, P. B., & Préat, V. (2021). Quality-by-Design-Based Development of a Voxelotor Self-Nanoemulsifying Drug-Delivery System with Improved Biopharmaceutical Attributes. Pharmaceutics, 13(9), 1388 [1-20]. https://doi.org/10.3390/pharmaceutics13091388 (Original work published 2021)
    • Xu, Y., Shrestha, N., Préat, V., & Beloqui Garcia, A. (2021). An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers. Advanced Drug Delivery Reviews. Accepted/in-press. https://doi.org/10.1016/j.addr.2021.05.005 (Original work published 2021)
  • 2020
    • Article de journal
      Buya, A. B., Beloqui Garcia, A., Memvanga, P., & Préat, V. (2020). Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery. Pharmaceutics, 12(12), 1194. https://doi.org/10.3390/pharmaceutics12121194 (Original work published 2020)
    • Plaza-Oliver, M., Beloqui Garcia, A., Santander-Ortega, M. J., Castro-Vázquez, L., Rodríguez-Robledo, V., Arroyo-Jiménez, M. M., Préat, V., & Lozano, M. V. (2020). Ascorbyl-dipalmitate-stabilised nanoemulsions as a potential localised treatment of inflammatory bowel diseases. International Journal of Pharmaceutics, 586, 119533. https://doi.org/10.1016/j.ijpharm.2020.119533 (Original work published 2020)
    • Huguet-Casquero, A., Xu, Y., Gainza, E., Pedraz, J. L., & Beloqui Garcia, A. (2020). Oral delivery of oleuropein-loaded lipid nanocarriers alleviates inflammation and oxidative stress in acute colitis. International Journal of Pharmaceutics, 586, 119515. https://doi.org/10.1016/j.ijpharm.2020.119515 (Original work published 2020)
    • Dumont, C., Beloqui Garcia, A., Miolane, C., Bourgeois, S., Préat, V., Fassi, H., & Jannin, V. (2020). Solid lipid nanocarriers diffuse effectively through mucus and enter intestinal cells - but where is my peptide? International Journal of Pharmaceutics, 586, 119581. https://doi.org/10.1016/j.ijpharm.2020.119581 (Original work published 2020)
    • Xu, Y., De Keersmaecker, H., Braeckmans, K., De Smedt, S., Cani, P., Préat, V., & Beloqui Garcia, A. (2020). Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment. Biomaterials, 255, 120209 [1-12]. https://doi.org/10.1016/j.biomaterials.2020.120209 (Original work published 2020)
    • Buya Banzenga, A., Ucakar, B., Beloqui Garcia, A., Memvanga, P., & Préat, V. (2020). Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDSs) for senicapoc. International Journal of Pharmaceutics, 580, 119180. https://doi.org/10.1016/j.ijpharm.2020.119180 (Original work published 2020)
    • Xu, Y., Van Hul, M., Suriano, F., Préat, V., Cani, P., & Beloqui Garcia, A. (2020). Novel strategy for oral peptide delivery in incretin-based diabetes treatment. Gut, 69(5), 911-919. https://doi.org/10.1136/gutjnl-2019-319146 (Original work published 2020)
    • Xu, Y., Shrestha, N., Préat, V., & Beloqui Garcia, A. (2020). Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems. Journal of controlled release : official journal of the Controlled Release Society, 322, 486-508. https://doi.org/10.1016/j.jconrel.2020.04.006 (Original work published 2020)

Anne des Rieux

  • 2026
    • Article de journal
      Moura Rui Pedro, Mwema, A., Bottemanne, P., Ucakar, B., Vanvarenberg, K., Pêgo, A. P., Muccioli, G., Sarmento, B., & des Rieux, A. (2026). Therapeutic potential of retinoic acid-loaded lipid Nanocapsules in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis. Journal of Controlled Release, 393, 114804. https://doi.org/10.1016/j.jconrel.2026.114804 (Original work published 2026)
    • Ma, Z., Dang, H. A., Yang, J., Rodella, G., Mwema, A., De Lombaerde, Chen, Y., De Geest, B. G., Van Pesch, V., Muccioli, G., & des Rieux, A. (2026). Lipid nanoparticle-mediated delivery of microRNA-124 reduces neuroinflammation. Biomaterials, 325, 123589. https://doi.org/10.1016/j.biomaterials.2025.123589 (Original work published 2026)
  • 2025
    • Article de journal
      Debuisson, F., Ucakar, B., Vanvarenberg, K., Delongie, K.-A., Haufroid, V., Mwema, A., & des Rieux, A. (2025). Nanomedicine-enhanced SCAP hybrid spheroids: A novel approach for improved stem cell survival. International Journal of Pharmaceutics, 675, 125503. https://doi.org/10.1016/j.ijpharm.2025.125503 (Original work published 2025)
    • Auquière, M., Terrasi, R., Gratpain, V., Vanderstraeten, J., Cronemberger-Andrade, A., Mozaheb, N., Mingeot-Leclercq, M.-P., des Rieux, A., & Muccioli, G. (2025). Critical evaluation of saponin as a permeabilizer for anandamide encapsulation in extracellular vesicles. Drug Delivery and Translational Research. Accepted/in-press. https://doi.org/10.1007/s13346-025-01951-4 (Original work published 2025)
    • Yang, J., des Rieux, A., & Malfanti, A. (2025). Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases. ACS Nano, 19(16), 15189-15219. https://doi.org/10.1021/acsnano.5c00700 (Original work published 2025)
    • Auquière, M., Muccioli, G., & des Rieux, A. (2025). Methods and Challenges in Purifying Drug‐Loaded Extracellular Vesicles. Journal of Extracellular Vesicles, 14(6), 1-20. https://doi.org/10.1002/jev2.70097 (Original work published 2025)
    • Boucq, P., Ucakar, B., Debuisson, F., Riva, R., des Rieux, A., Jérôme, C., & Debuigne, A. (2025). High Internal Phase Emulsion-Templated Hydrophilic Polyphosphoester Scaffolds: Tailoring the Porosity and Degradation for Soft Tissue Engineering. Biomacromolecules, 26(3), 1935-1947. https://doi.org/10.1021/acs.biomac.4c01740 (Original work published 2025)
    • Yang, J., Ucakar, B., Vanvarenberg, K., Malfanti, A., & des Rieux, A. (2025). Nanoparticles loaded with a CSF1R antagonist selectively depletes microglial cells and modulates inflammation in spinal cord injury. Journal of Controlled Release, 386, 114079. https://doi.org/10.1016/j.jconrel.2025.114079 (Original work published 2025)
  • 2024
    • Article de journal
      Gratpain, V., Loriot, A., d’Auria, L., Bottemanne, P., Payen, V., Terrasi, R., Van Pesch, V., Muccioli, G., & des Rieux, A. (2024). Influence of a pro-inflammatory stimulus on the miRNA and lipid content of human dental stem cell-derived extracellular vesicles and their impact on microglial activation. Heliyon, 10(5), e27025 [1-14]. https://doi.org/10.1016/j.heliyon.2024.e27025 (Original work published 2024)
    • Labrak, Y., Al Houayek, M., Mwema, A., d’Auria, L., Ucakar, B., Van Pesch, V., Muccioli, G., & des Rieux, A. (2024). The combined administration of LNC-encapsulated retinoic acid and calcitriol stimulates oligodendrocyte progenitor cell differentiation in vitro and in vivo after intranasal administration. International Journal of Pharmaceutics, 659, 124237 [1-9]. https://doi.org/10.1016/j.ijpharm.2024.124237 (Original work published 2024)
    • Mwema, A., Gratpain, V., Ucakar, B., Vanvarenberg, K., Perdaens, O., Van Pesch, V., Muccioli, G., & des Rieux, A. (2024). Impact of calcitriol and PGD2-G-loaded lipid nanocapsules on oligodendrocyte progenitor cell differentiation and remyelination. Drug Delivery and Translational Research, 14(11), 3128-3146. https://doi.org/10.1007/s13346-024-01535-8 (Original work published 2024)
  • 2023
    • Article de journal
      Moura, R. P., Carvalho, E. D., Martins, C., des Rieux, A., Pêgo, A. P., & Sarmento, B. (2023). Functionalized retinoic acid lipid nanocapsules promotes a two-front attack on inflammation and lack of demyelination on neurodegenerative disorders. Journal of controlled release : official journal of the Controlled Release Society, 358, 43-58. https://doi.org/10.1016/j.jconrel.2023.04.034 (Original work published 2023)
    • Nativel, F., Smith, A., Boulestreau, J., Lépine, C., Baron, J., Marquis, M., Vignes, C., Le Guennec, Y., Veziers, J., Lesoeur, J., Loll, F., Halgand, B., Renard, D., Abadie, J., Legoff, B., Blanchard, F., Gauthier, O., Vinatier, C., des Rieux, A., et al. (2023). Micromolding-based encapsulation of mesenchymal stromal cells in alginate for intraarticular injection in osteoarthritis. Materials today. Bio, 19, 100581. https://doi.org/10.1016/j.mtbio.2023.100581 (Original work published 2023)
    • Mwema, A., Bottemanne, P., Paquot, A., Ucakar, B., Vanvarenberg, K., Al Houayek, M., Muccioli, G., & des Rieux, A. (2023). Lipid nanocapsules for the nose-to-brain delivery of the anti-inflammatory bioactive lipid PGD-G. Nanomedicine : nanotechnology, biology, and medicine, 48, 102633. https://doi.org/10.1016/j.nano.2022.102633 (Original work published 2023)
    • Balcaen, T., Piens, C., Mwema, A., Chourrout, M., Vandebroek, L., des Rieux, A., Chauveau, F., De Borggraeve, W. M., Hoffmann, D., & Kerckhofs, G. (2023). Revealing the three-dimensional murine brain microstructure by contrast-enhanced computed tomography. Frontiers in neuroscience, 17, 1141615 [1-15]. https://doi.org/10.3389/fnins.2023.1141615 (Original work published 2023)
    • Mwema, A., Muccioli, G., & des Rieux, A. (2023). Innovative drug delivery strategies to the CNS for the treatment of multiple sclerosis. Journal of controlled release : official journal of the Controlled Release Society, 364, 435-457. https://doi.org/10.1016/j.jconrel.2023.10.052 (Original work published 2023)
  • 2022
    • Article de journal
      Chiti, M.-C., Vanacker, J., Ouni, E., Tatic, N., Viswanath, A., des Rieux, A., Dolmans, M.-M., White, L. J., & Andrade Amorim, C. (2022). Ovarian extracellular matrix-based hydrogel for human ovarian follicle survival in vivo: A pilot work. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 110(5), 1012-1022. https://doi.org/10.1002/jbm.b.34974 (Original work published 2022)
    • De Berdt, P., Vanvarenberg, K., Ucakar, B., Bouzin, C., Paquot, A., Gratpain, V., Loriot, A., Payen, V., Bearzatto, B., Muccioli, G., Gatto, L., Diogenes, A., & des Rieux, A. (2022). The human dental apical papilla promotes spinal cord repair through a paracrine mechanism. Cellular and molecular life sciences : CMLS, 79(5), 252. https://doi.org/10.1007/s00018-022-04210-8 (Original work published 2022)
    • Xu, Y., Fourniols, T., Labrak, Y., Préat, V., Beloqui Garcia, A., & des Rieux, A. (2022). Surface Modification of Lipid-Based Nanoparticles. ACS Nano, 16, 7168-7196. https://doi.org/10.1021/acsnano.2c02347 (Original work published 2022)
    • Gilli, M., Hollaert, T. G., Setbon, H., des Rieux, A., & Leprince, J. (2022). Quality of Cure in Depth of Commercially Available Bulk-fill Composites: A Layer-by-layer Mechanical and Biological Evaluation. Operative Dentistry, 47(4), 437-448. https://doi.org/10.2341/21-084-L (Original work published 2022)
    • Labrak, Y., Heurtault, B., Frisch, B., Saulnier, P., Lepeltier, E., Miron, V. E., Muccioli, G., & des Rieux, A. (2022). Impact of anti-PDGFRα antibody surface functionalization on LNC uptake by oligodendrocyte progenitor cells. International Journal of Pharmaceutics, 618, 121623. https://doi.org/10.1016/j.ijpharm.2022.121623 (Original work published 2022)
  • 2021
    • Article de journal
      Gratpain, V., Mwema, A., Labrak, Y., Muccioli, G., Van Pesch, V., & des Rieux, A. (2021). Extracellular vesicles for the treatment of central nervous system diseasesExtracellular vesicles for the treatment of central nervous system diseases. Advanced Drug Delivery Reviews, 174, 535-552. https://doi.org/10.1016/j.addr.2021.05.006 (Original work published 2021)
    • Del Vento, F., Poels, J., Vermeulen, M., Ucakar, B., Giudice, M. G., Kanbar, M., des Rieux, A., & Wyns, C. (2021). Accelerated and Improved Vascular Maturity after Transplantation of Testicular Tissue in Hydrogels Supplemented with VEGF- and PDGF-Loaded Nanoparticles. International Journal of Molecular Sciences, 22(11), 5779 [1-17]. https://doi.org/10.3390/ijms22115779 (Original work published 2021)
    • des Rieux, A. (2021). Stem cells and their extracellular vesicles as natural and bioinspired carriers for the treatment of neurological disorders. Current Opinion in Colloid & Interface Science, 54, 101460. https://doi.org/10.1016/j.cocis.2021.101460 (Original work published 2021)
  • 2020
    • Article de journal
      Somville, E., Kumar, A. A., Guicheux, J., Halgand, B., Demoustier, S., des Rieux, A., Jonas, A., & Glinel, K. (2020). Green and Tunable Animal Protein-Free Microcarriers for Cell Expansion. ACS Applied Materials and Interfaces, 12(45), 50303-50314. https://doi.org/10.1021/acsami.0c16875 (Original work published 2020)
    • Moura, R. P., Pacheco, C., Pêgo, A. P., des Rieux, A., & Sarmento, B. (2020). Lipid nanocapsules to enhance drug bioavailability to the central nervous system. Journal of Controlled Release, 322, 390-400. https://doi.org/10.1016/j.jconrel.2020.03.042 (Original work published 2020)
    • Alevra Sarika, N., Payen, V., Fléron, M., Ravau, J., Brusa, D., Najimi, M., De Pauw, E., Eppe, G., Mazzucchelli, G., Sokal, E., des Rieux, A., & El Taghdouini, A. (2020). Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells. Cells, 9(6), 1357 [1-19]. https://doi.org/10.3390/cells9061357 (Original work published 2020)
    • Kandalam, S., De Berdt, P., Ucakar, B., Vanvarenberg, K., Bouzin, C., Gratpain, V., Diogenes, A., Montero-Menei, C. N., & des Rieux, A. (2020). Human dental stem cells of the apical papilla associated to BDNF-loaded pharmacologically active microcarriers (PAMs) enhance locomotor function after spinal cord injury. International Journal of Pharmaceutics, 587, 119685. https://doi.org/10.1016/j.ijpharm.2020.119685 (Original work published 2020)
    • Carradori, D., Labrak, Y., Miron, V. E., Saulnier, P., Eyer, J., Préat, V., & des Rieux, A. (2020). Retinoic acid-loaded NFL-lipid nanocapsules promote oligodendrogenesis in focal white matter lesion. Biomaterials, 230, 119653 [1-11]. https://doi.org/10.1016/j.biomaterials.2019.119653 (Original work published 2020)

Rita Vanbever

  • 2026
    • Article de journal
      Buzisa Mbuku, R., Poilvache, H., Maigret, L., Vanbever, R., Van Bambeke, F., & Cornu, O. (2026). Enzymes-enhanced antibiotic therapy reduces biofilms to undetectable levels in an implant-associated infection model. NPJ biofilms and microbiomes, 12(1), 44 [1-15[. https://doi.org/10.1038/s41522-026-00910-2 (Original work published 2026)
  • 2025
    • Article de journal
      Leone, G., Ucakar, B., Perros, F., Frédérick, R., & Vanbever, R. (2025). Synthesis and in vitro evaluation of polyethylene glycol-treprostinil conjugates for sustained local delivery in pulmonary arterial hypertension. European Journal of Pharmaceutical Sciences, 214, 107287. https://doi.org/10.1016/j.ejps.2025.107287 (Original work published 2025)
    • Liu, X., Ucakar, B., Vanvarenberg, K., Marbaix, E., & Vanbever, R. (2025). Impact of administration route and PEGylation on alpha-1 antitrypsin augmentation therapy. Journal of Controlled Release, 382, 113643. https://doi.org/10.1016/j.jconrel.2025.113643 (Original work published 2025)
    • Buzisa Mbuku, R., Poilvache, H., Maigret, L., Vanbever, R., Van Bambeke, F., & Cornu, O. (2025). Targeting Staphylococcus aureus biofilm-related infections on implanted material with a novel dual-action thermosensitive hydrogel containing vancomycin and a tri-enzymatic cocktail: in vitro and in vivo studies. Biofilm, 9(9), 100288. https://doi.org/10.1016/j.bioflm.2025.100288 (Original work published 2025)
    • Leone, G., Ucakar, B., Perros, F., Frédérick, R., & Vanbever, R. (2025). Synthesis and in vitro evaluation of polyethylene glycol-treprostinil conjugates for sustained local delivery in pulmonary arterial hypertension. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 214(11), 107287. https://doi.org/10.1016/j.ejps.2025.107287 (Original work published 2025)
  • 2024
    • Article de journal
      Wang, Z., Vanbever, R., Lorent, J. H., Solis, J., Knoop, C., & Van Bambeke, F. (2024). Repurposing DNase I and alginate lyase to degrade the biofilm matrix of dual-species biofilms of Staphylococcus aureus and Pseudomonas aeruginosa grown in artificial sputum medium: In-vitro assessment of their activity in combination with broad-spectrum antibiotics. Journal of Cystic Fibrosis, Feb213(none), S1569-1993. https://doi.org/10.1016/j.jcf.2024.02.012 (Original work published 2024)
    • Redeghieri, P., Moray, J., Kerff, F., Gohy, S., Leal, T., Muyldermans, S., Morales-Yánez, F. J., Vanbever, R., & Dumoulin, M. (2024). Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties. Protein science, 33(12), e5227 [1-22]. https://doi.org/10.1002/pro.5227 (Original work published 2024)
    • Mahri, S., Cassiers, C., Gracin, S., Tyteca, D., Uwambayinema, F., Huaux, F., Ibrahim, M., Piper, S., Llinas, A., Fridén, M., & Vanbever, R. (2024). Impact of protein aggregation on the immunogenicity of a human monoclonal antibody following pulmonary administration in mice. International Journal of Pharmaceutics, 667(Pt B), 124880 [1-13]. https://doi.org/10.1016/j.ijpharm.2024.124880 (Original work published 2024)
  • 2023
    • Article de journal
      Brancaleone, P., Delefortrie, Q., Descamps, O., Weynand, B., Vanbever, R., & Detry, G. (2023). Lipoid Pneumonia Associated with Polyethylene Glycol Chronic Aspiration. American Journal of Respiratory and Critical Care Medicine, 207 (8), e71-e72. https://doi.org/10.1164/rccm.202107-1692IM (Original work published 2023)
    • Mahri, S., Wilms, T., Hagedorm, P., Guichard, M.-J., Vanvarenberg, K., Dumoulin, M., Frijlink, H., & Vanbever, R. (2023). Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study. European Journal of Pharmaceutical Sciences, 189, 106522 [1-10]. https://doi.org/10.1016/j.ejps.2023.106522 (Original work published 2023)
  • 2022
    • Article de journal
      Liu, X., Vanvarenberg, K., Kouassi, W., Mahri, S., & Vanbever, R. (2022). Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy. International Journal of Pharmaceutics, 612, 121355. https://doi.org/10.1016/j.ijpharm.2021.121355 (Original work published 2022)
    • Liu, X., Kouassi, K., Vanbever, R., & Dumoulin, M. (2022). Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal and proteolytic stability of mono-PEGylated alpha-1 antitrypsin. Protein Science. Accepted/in-press. (Original work published 2022)
    • Reynaerts, A., Vermeulen, F., Mottais, A., Gohy, S., Lebecque, P., Frédérick, R., Vanbever, R., & Leal, T. (2022). Needle-free iontophoresis-driven β-adrenergic sweat rate test. Journal of Cystic Fibrosis, 21(3), 407-415. https://doi.org/10.1016/j.jcf.2021.08.012 (Original work published 2022)
  • 2021
    • Article de journal
      Loira Pastoriza, C., Vanvarenberg, K., Ucakar, B., Machado, M., Staub, A., Lemaire, M., Renauld, J.-C., & Vanbever, R. (2021). Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer. International Journal of Pharmaceutics, 600, 120504. https://doi.org/10.1016/j.ijpharm.2021.120504 (Original work published 2021)
    • Vanbever, R., & Champion, J. (2021). Natural and Bioinspired Carriers for Therapeutic Delivery. Current Opinion in Colloid & Interface Science, 101533. https://doi.org/10.1016/j.cocis.2021.101533 (Original work published 2021)
    • Mahri, S., Hardy, E., Wilms, T., De Keersmaecker, H., Braeckmans, K., De Smedt, S., Bosquillon, C., & Vanbever, R. (2021). PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages. International Journal of Pharmaceutics, 593, 120107. https://doi.org/10.1016/j.ijpharm.2020.120107 (Original work published 2021)
    • Rondon, A., Mahri, S., Morales‐Yanez, F., Dumoulin, M., & Vanbever, R. (2021). Protein Engineering Strategies for Improved Pharmacokinetics. Advanced Functional Materials, 2101633. https://doi.org/10.1002/adfm.202101633 (Original work published 2021)
    • Mahri, S., Rondon, A., Wilms, T., Bosquillon, C., & Vanbever, R. (2021). Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice. Journal of controlled release : official journal of the Controlled Release Society, 329, 1054-1065. https://doi.org/10.1016/j.jconrel.2020.10.034 (Original work published 2021)
    • Guichard, M.-J., Wilms, T., Mahri, S., Patil, H. P., Hoton, D., Ucakar, B., Vanvarenberg, K., Cheou, P., Beka, M., Marbaix, E., Leal, T., & Vanbever, R. (2021). PEGylation of recombinant human deoxyribonuclease I provides a long‐acting version of the mucolytic for patients with cystic fibrosis. Advanced therapeutics, 4(2), 2000146. https://doi.org/10.1002/adtp.202000146 (Original work published 2021)
  • 2020
    • Article de journal
      Scarcello, E., Lambremont, A., Vanbever, R., Jacques, P., & Lison, D. (2020). Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese. PLoS One, 15(4), e0231634 [1-14]. https://doi.org/10.1371/journal.pone.0231634 (Original work published 2020)

Véronique Préat