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Theses

ldri | Bruxelles Woluwe

Theses in progress

Autuori Manon 
Breath volatolome as a new tool to study gut microbiome – nutrition – host interactions
Director: Nathalie M. Delzenne

Barbé Alice 
Impact of antibiotic treatments on tacrolimus pharmacokinetics in renal transplant patients - potential influence of gut microbiota
Director: Laure Elens; Co-directors: Françoise Van Bambeke and Laure Bindels

Cauwelier Claire
Studying the Effect of Hydrolysates containing Bio-active Peptides in Murine Models of Intestinal Inflammation and Obesity
Director: Nathalie Delzenne

Dufour Inès
Association of Cachexia and Gut Microbiome in Dialysis Patients: Investigation of the Interactions with Uremic Toxins and Inflammation
Director: Laure Bindels

Eeckhout Savannah 
Bacterial Amino Acid metabolites against Muscle wasting (bAAm/M)
Director: Laure B. Bindels

Fayt Clémence
Roles of gut microbes in inter-individual food reward dysregulations during nutritional obesity
Director: Amandine Everard

Kouakou Axell-Natalie
Study of the links between obesity, gut microbiota and melanoma progression and response to therapy
Directors: Bénédcite Jordan, Giulio Muccioli, Patrice D. Cani

Lecop Sophie
Evaluation of the impact of new probiotic candidates on the gut barrier function in the context of cancer cachexia
Director: Laure Bindels

Lee Chi-Hsien 
Isolating and characterizing new microbes from the human gut to improve health
Director: Patrice D. Cani

Mutoni Jean d’Amour
Relationships between parasite infections and gut microbiota : experimental models and clinical study
Directors: Patrice D. Cani, Jean-Paul Coutelier, Nadine Rujeni

Nobels Amandine
Ciclibiome, an exploration of the interactions between microbiome, circulating metabolism and immunity in HR-positive HER2-negative breast cancer treated with a CDK4/6 inhibitor
Director: Patrice Cani

Piron Edwige
Targeting bacterial metabolites to tackle muscle wasting in colorectal cancer-associated cachexia: toward a mechanistic understanding
Director: Laure Bindels

Stevens Philippe
Microbiome and tumor immune micro-environment: characterization and interaction during progression and treatment of advanced and metastatic colorectal cancer
Directors: Marc Van den Eynde and Patrice D. Cani

Uwimana Aline
Impact of nutrition on the outcome of malaria infection.
Directors: Léon Mutesa and Amandine Everard

Viera Olivera Eloise
Interest of volatolome analysis in the elucidation of gut microbiota-host interaction in nutrition and health
Director: Nathalie Delzenne

2024

Huwart Sabrina
Role of gut microbiota components-induced neuroinflammation on food reward alterations during obesity
Director: Amandine Everard

2023

Degraeve Alexandra 
Tacrolimus pharmacokinetics and gut microbiota: from mechanistic to clinical investigations
Directors: Laure Elens and Laure B. Bindels

Gillard Justine
Bile acids and the enterohepatic cycle : from old dogmas to new potential therapeutic targets for non-alcoholic steatohepatitis
Directors: Isabelle Leclercq and Laure B. Bindels

Moens de Hase Emilie
Investigation of the effects of the newly discovered Dysosmobacter welbionis J115T on metabolism and inflammation
Director : Patrice Cani

Paone Paola
Unravelling the mechanisms by which prebiotics improve metabolic disorders : interactions between gut microbes and intestinal mucus
Director: Patrice D. Cani

Yalek Caner
Obesity-associated alterations driving breast cancer progression : understanding the role of the gut microbiota and characterizing tumor metabolism
Directors: Bénédicte Jordan and Patrice D. Cani.

2022

Amadieu Camille
Gut microbiota, biological and psychological alterations in alcohol use disorder
Directors: Nathalie M. Delzenne, Philippe de Timary, and Sophie Leclercq

Bachmann Radu
The influence of Akkermansia muciniphila on intestinal wound healing
Directors: Patrice D. Cani and Alex Kartheuser

de Wouters Alice
Roles of gut microbes in the gut-to-brain axis controlling hedonic/reward responses to food intake in physiological condition and in the pathology of obesity
Directors: Amandine Everard and Patrice D. Cani

Pötgens Sarah
Exploration of the contribution of the gut microbiota and its metabolism to cancer cachexia
Director: Laure B. Bindels

Thibaut Morgane
Contribution of the alterations in bile acid pathways to cancer cachexia
Director: Laure B. Bindels

2020

Depommier Clara
Investigation of the impact of Akkermansia muciniphila on cardiometabolic disorders associated with obesity : from pre-clinical investigation to human intervention
Directors: Patrice D. Cani and Amandine Everard

Gourgue Florian
Investigation of the apelin adipokine as a potential therapeutic target for breast cancer patients in the context of obesity
Directors: Bénédicte Jordan and Patrice D. Cani.

Lefort Charlotte
Hepatocyte endocannabinoid system and innate immunity influence whole-body lipid metabolism : investigation of the molecular mechanisms in the context of obesity
Director: Patrice D. Cani.

Rastelli Marialetizia
Intestinal epithelial NAPE-PLD controls food intake and energy homeostasis in response to dietary lipids : insight on the mechanisms
Director: Patrice D. Cani.

2019

Hiel Sophie 
Interest of native inulin in the modulation of dysbiosis and metabolic alterations: experimental approach and nutritional interventions in humans.
Director: Nathalie M. Delzenne and Jean-Paul Thissen

2018

Suriano Francesco 
Potential use of wheat bran products in the management of metabolic disorders : implication of the gut microbiota
Director: Nathalie M. Delzenne

2017

Catry Emilie
Role of the gut microbiota in the control of cardiometabolic risk
Director: Nathalie M. Delzenne

Plovier Hubert
Impact of Akkermansia muciniphila and the intestinal endocannabinoid system on the metabolic syndrome
Director: Patrice D. Cani

2015

Geurts Lucie
Impact of the gut microbiota on the adipose tissue-endocannabinoid system: role on the development of obesity and associated inflammation
Director: Patrice D. Cani

Leclercq Sophie
New targets in the management of alcohol dependence : which role for gut microbiota, gut barrier and immunity ?
Director: Nathalie Delzenne