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Theses

ldri | Bruxelles Woluwe

THESES IN PROGRESS

Auquière Marie
Encapsulation of lipids and microARNs in extracellular vesicles for the treatment of multiple sclerosis
Directors : Anne des Rieux and Giulio Muccioli

Cheng Chen
Metal-organic framework for oral antibody delivery for inflammatory bowel disease and colorectal cancer treatment
Director : Ana Beloqui Garcia

Debuisson Floriane
Mesenchymal stem cells delivery in hybrid spheroids for treatment of spinal cord injury: innovative formulation and pre-clinical perspectives.”
Director: Anne des Rieux (ADDB/LDRI)

Detroz Fanny
Development of nanomedicines to tackle cystic fibrosis lung disease
Directors Rita Vanbever and Mireille Dumoulin (ULiège)

Guilbaud Léo
Exploiting the cGAS-STING pathway as therapeutic target in inflammatory bowel disease treatment
Director: Ana Beloqui (ADDB/LDRI); Co-director: Alessio Malfanti (ADDB/LDRI)

Hendrickx Pauline
Programmable Biomaterials Laboratory/EPFL - Exploring the use of DNA nanotechnology for the cytoplasmic delivery of therapeutic miRNA for spinal cord injury repair
Director : Anne des Rieux

Hoflack Laurie
Development and pharmacological assessment of a dual nanocarrier containing pro-resolutive drugs in models of rheumatoid arthritis
Directors : Mireille Al Houayek and Ana Beloqui Garcia

Ladeiro Domingues Inês
Exploiting the biological effect exerted by nanocarriers in non-alcoholic fatty liver disease treatment.
Director: Ana Beloqui (ADDB/LDRI); Co-Director: Isabelle Leclercq (GAEN/IREC)

Lemaire Lorine
Design of an anti-elastase nanomedicine to prevent the evolution of emphysema in chronic obstructive pulmonary disease
Director: Rita Vanbever (ADDB/LDRI)

Leone Giuditta
Design of a long-acting vasodilator nanomedicine for inhalation in pulmonary arterial hypertension.
Director: Rita Vanbever (ADDB/LDRI) - Co-Director: Raphaël Frédérick (CMFA/LDRI)

Ma Zhanjun
Taking the best of two worlds to treat spinal cord injury: traditional Chinese medicine Rosmarinic acid combined with stem cell derived-extracellular vesicles
Director : Anne des Rieux

Marotti Valentina
Gene silencing of TNFα in inflammatory bowel disease treatment through a dual-shielding strategy via bioadhesive beads”.
Director: Ana Beloqui (ADDB/LDRI); Co-Director: Alessio Malfanti (ADDB/LDRI)

Parrens Paul
Engineering bacterocin-based nanomedicines for the eradication of Staphylococcus aureus intracellular reservoirs in the context of skin chronic infections
Director: Rita Vanbever (ADDB/LDRI); Co-director: Françoise Van Bambeke (TFAR FACM/LDRI)

Redeghieri Paola
Nanobodies to target proteases involved in inflammatory diseases of the lungs
Director: Mireille Dumoulin (Center for protein engineering, ULiège); Co-Director: Rita Vanbever (ADDB/LDRI)

Rodella Giulia
Design of hyaluronic acid-based chemo-immunotherapy for glioblastoma treatment
Directors: Alessio Malfanti (ADDB/LDRI) and Bernard Gallez (REMA/LDRI)

Van den Bossche William
Gas-promoted microbubbles-based drug delivery systems for the delivery of biologics in inflammatory bowel disease treatment
Director: Ana Beloqui (ADDB/LDRI)

Yang Jingjing
Development of rationally-designed stimuli-responsive nanoparticles for neuroprotective purposes in spinal cord injury repair
Directors : Anne des Rieux and Giulio Muccioli

 

2025

Zhang Wunan
Gas-promoted in situ bioadhesive foam platform for efficient macromolecule delivery in the treatment of inflammatory bowel disease
Director: Ana Beloqui (ADDB/LDRI)

2024

Conq Jérôme
Assessment of strategies for a blood-brain barrier opening in glioblastoma.
Director: Bernard Gallez (REMA/LDRI); Co-Director: Véronique Préat (ADDB/LDRI)

Gratpain Viridiane
Siponimod-loaded extracellular vesicles to stimulate remyelination in the central nervous system .
Director: Anne des Rieux (ADDB/LDRI)

Kambale Kavungere Espoir
Green-synthesis of zinc oxide nanoparticles for the treatment of type 2 diabetes mellitus
Director: Ana Beloqui (ADDB/LDRI); Co-directors: Joëlle Leclercq (GNOS/LDRI), MEMVANGA BONDO Patrick (UNIKIN)

2023

Mwema Ariane
Nose-to-Brain Delivery of Nanomedicines to stimulate remyelination in the scope of multiple sclerosis.
Director: Anne des Rieux (ADDB/LDRI); Co-Director: Giulio Muccioli (ADDB/LDRI)

Wang Mingchao
Development of doxorubicin based-nanomedicine for the local treatment of glioblastoma
Director: Véronique Préat (ADDB/LDRI); Co-Director: Chiara Bastiancich (ADDB/LDRI)

2022

Bausart Mathilde
Combination of immunotherapy and local chemotherapy for the treatment of unresectable glioblastoma.
Directors: Véronique Préat; Alessio Malfanti (ADDB/LDRI)

Beauquis Julien
Understanding and management of the mechanisms of pulp inflammation.
Director: Gaëtane Leloup (ADDB/LDRI); Co-Director: Julian Leprince (ADDB/LDRI)

Liu Xiao
Development of a long-acting version of Alpha1 antitrypsin for augmentation therapy in Alpha1 antitrypsin deficiency.
Director: R. Vanbever (ADDB/LDRI)

Labrak Yasmine
Targeted nanomedicines to stimulate the differentiation of oligodendrocyte progenitor cells in the scope of multiple sclerosis.
Director: Anne des Rieux (ADDB/LDRI); Co-Director: Giulio Muccioli (BPBL/LDRI)

2021

Buya Aristote
Self-emulsifying systems for the oral delivery of anti-sickling agents.
Director: Véronique Préat (ADDB/LDRI); Co-Director: Patrick Menvanga (Universté de Kinshasa)

Bozzato Elia
Multi-drug loaded nanomedicine hydrogel for the treatment of glioblastoma.
Director: Véronique Préat (ADDB/LDRI); Co-Director: Chiara Bastiancich

Hardy Chloé
Optimize the strategy of indirect bonded restorations to restore an endodontically-treated molar as a unit.
Director: Gaëtane Leloup (ADDB/LDRI); Co-Director: Julian Leprince (ADDB/LDRI)

Tatic Natalja
Modulation of macrophage phenotype for spinal cord repair.
Director: Anne des Rieux (ADDB/LDRI) - Co-director: Lisa White (Univ. Nottingham)

Tsakiris Nikolaos
Drugs-loaded lipid nanocapsules for the treatment of colorectal cancer
Director : Véronique Préat - Co-director : Arnaud Vigneron (Université de Lyon)

Xu Yining
Peptide-loaded nanoparticle oral delivery strategies towards diabetes treatment
Director Ana Beloqui - Co-director : Véronique Préat (ADDB/LDRI)

2020

Fourniols Thibaut
Lipid nanocapsules as a delivery platform to tackle colorectal cancer microenvironment
Director: Véronique Préat

Mahri Sohaib
Mechanisms of retention of PEGylated recombinant human deoxyribonuclease (rhDNase) in the lungs
Director: R. Vanbever (ADDB/LDRI) - Co-director: C Bosquillon (Univ. Nottingham)

2019

Ganipineni Pallavi
Multifunctional poly(lactic-co-glycolic acid) based nanoparticles for targeting and treating glioblastoma.
Director: Véronique Préat (ADDB/LDRI)

Germain Loïc
Macroporous scaffolds for tissue engineering: 3D printing & modification of the surface mechanical properties.
Directors: Anne des Rieux (ADDB/LDRI); Christine Dupont-Gillain (IMCN)

Lopes Alessandra
From molecular optimization to therapy combination: novel strategies to improve cancer DNA vaccines.
Director: Véronique Préat (ADDB/LDRI); Co-director: Gaëlle Vandermeulen

Zhao Mengnan
Anticancer drug-loaded photopolymerizable hydrogel for the treatment of glioblastoma.
Director: Véronique Préat (ADDB/LDRI)

2018

Bastiancich Chiara
Lauroyl-gemcitabine lipid nanocapsule hydrogel for the local treatment of glioblastoma.
Directors: Véronique Préat (ADDB/LDRI)

De Berdt Pauline
Spinal Cord Injury: How could dental stem cells from human apical papilla take up the challenge?.
Director: Anne des Rieux (ADDB/LDRI)

Guichard Marie-Julie
Development of a long-acting version of recombinant human deoxyribonuclease I for the treatment of cystic fibrosis lung disease.
Director: Rita Vanbever (ADDB/LDRI)

2017

Carradori Dario
Novel nanoparticle-based drug delivery system for neural stem cell targeting and differentiation.
Directors : Anne des Rieux (ADDB/LDRI) & Joël Eyer (Univ. Angers)

Kalichuk Valentina
A novel generation of Affitins for targeting cancer cells with drug-loaded lipid nanocapsules.
Directors: Véronique Préat (ADDB/LDRI) & Frédéric Pecorari (Univ. Nantes)

Kandalam Saikrishna
Pharmacologically active microcarriers delivering brain-derived neurotrophic factor combined to adult mesenchymal stem cells: novel approach for the treatment of spinal cord injury.
Director: Anne des Rieux (ADDB/LDRI); Co-Director: Claudia Montero-Menei (Université d'Angers)

Lambricht Laure
Plasmids encoding viral structural proteins to enhance cancer DNA vaccine potency.
Directors: Véronique Préat - Gaëlle Vandermeulen (ADDB/LDRI)

Randolph Luc
Changing camphorquinone for a more efficient photo-initiator in dental filled resins.
Directors: Gaëtane Leloup; Julian Leprince

Viswanath Aiswarya
Dental stem cell delivery through new injectable matrices for spinal cord regeneration.
Directors : Anne des Rieux (ADDB/LDRI); Kevin Shakesheff (Univ. Nottingham)

2016

Jully Vanessa
Development of a High-Throughput Screening Platform for the Formulation of Alun Adjuvanted Vaccines.
Directors: V. Préat (ADDB/LDRI), N. Moniotte (GSK)

Thwala Lungile
Protamine nanocapsules as carriers for oral peptide delivery.
Director: V. Préat (ADDB/LDRI); Co-Director: Maria José Alonso (Spain).

Tian Luo
PEGylation of paclitaxel for inhaled chemotherapy.
Directors: R. Vanbever (ADDB/LDRI), C. Bosquillon (Univ. Nottingham)

2015

Chereddy Kiran
Drug loaded poly(lactic-co-glycolic acid) nanoparticles for wound healing activity.
Director: V. Préat (ADDB/LDRI)

Jacobs Damien
Characterization of Wallerian degeneration by in vivo diffusion compartment imaging.
Directors: B. Macq (ICTM/ELEN), A. des Rieux (ADDB/LDRI), B. Gallez (REMA/LDRI)

Schleich Nathalie
Dual paclitaxel / superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging.
Director: V. Préat (ADDB/LDRI)