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Publications

libst | Louvain-la-Neuve

  • Journal article
    • 2025
      Gatreddi, Santhosh ; Urdiain-Arraiza, Julian ; Desguin, Benoit ; Hausinger, Robert P. ; Hu, Jian.
      Structural Basis for the Catalysis and Substrate Specificity of a LarA Racemase with a Broad Substrate Spectrum. In: ACS Catalysis, p. 2857-2866 (2025). doi:10.1021/acscatal.4c07804 (Accepté/Sous presse).
    • 2024
      Vucko, Timothé ; Strilets, Dmytro ; Soumillion, Patrice ; Desguin, Benoît ; Vincent, Stéphane P.
      Chemo-enzymatic synthesis of NPN cofactor taking advantage of ADP-ribosyl cyclase and LarC cyclometallase promiscuous activities.. In: Bioorganic chemistry, Vol. 153, p. 107879 (2024). doi:10.1016/j.bioorg.2024.107879.
    • Dorrazehi, Gol Mohammad ; Winkle, Matthias ; Desmet, Martin ; Stroobant, Vincent ; Tanriver, Gamze ; Degand, Hervé ; Evrard, Damien ; Desguin, Benoît ; Morsomme, Pierre ; Biboy, Jacob ; Gray, Joe ; Mitusińska, Karolina ; Góra, Artur ; Vollmer, Waldemar ; Soumillion, Patrice.
      PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, exhibits pH-dependent promiscuous activity harmful to Escherichia coli.. In: Scientific reports, Vol. 14, no. 1, p. 13999 (2024). doi:10.1038/s41598-024-64806-x.
    • Urdiain-Arraiza, Julian ; Vandenberghe, Amandine ; Dimitrova, Gergana ; Desguin, Benoît.
      Unveiling 14 novel 2-hydroxy acid racemization and epimerization reactions in the lactate racemase superfamily. In: The Journal of biological chemistry, Vol. 301, no.1, p. 108069 (2024). doi:10.1016/j.jbc.2024.108069.
    • Urdiain-Arraiza, Julian ; Desguin, Benoît.
      Versatile capillary electrophoresis method for the direct chiral separation of aliphatic and aromatic α-hydroxy acids, β-hydroxy acids and polyhydroxy acids using vancomycin as chiral selector. In: Journal of Chromatography A, Vol. 1715, no. 464611, p. 1-13 (2024). doi:10.1016/j.chroma.2023.464611.
    • 2023
      Gatreddi, Santhosh ; Urdiain-Arraiza, Julian ; Desguin, Benoît ; Hausinger, Robert P ; Hu, Jian.
      Structural and mutational characterization of a malate racemase from the LarA superfamily.. In: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 36, no.2, p. 303-313 (2023). doi:10.1007/s10534-022-00372-x.
    • 2021
      Rankin, Joel A ; Chatterjee, Shramana ; Tariq, Zia ; Lagishetty, Satyanarayana ; Desguin, Benoît ; Hu, Jian ; Hausinger, Robert P.
      The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 118, no.39, p. e2106202118 (2021). doi:10.1073/pnas.2106202118.
    • 2020
      Desguin, Benoît ; Urdiain-Arraiza, Julian ; Da Costa, Matthieu ; Fellner, Matthias ; Hu, Jian ; Hausinger, Robert P ; Desmet, Tom ; Hols, Pascal ; Soumillion, Patrice.
      Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.. In: Scientific reports, Vol. 10, no.1, p. 18123 (2020). doi:10.1038/s41598-020-74802-6.
  • Book chapter
    • 2023
      Hausinger, Robert P ; Hu, Jian ; Desguin, Benoît.
      The nickel-pincer coenzyme of lactate racemase: A case study of uncovering cofactor structure and biosynthesis.. In: John P. Richard and Graham R. Moran (eds.), New Experimental Probes for Enzyme Specificity and Mechanism (Methods in Enzymology; 685), Academic Press: Massachusetts, 2023, p. 341-371. 9780443152764. doi:10.1016/bs.mie.2023.03.006.
    • 2020
      Desguin, Benoît.
      LarC Cyclometallase. In: Robert A Scott, John Wiley & Sons, Encyclopedia of Inorganic and Bioinorganic Chemistry, 2020. 9781119951438. doi:10.1002/9781119951438.eibc2737.
  • Conference paper