Publications

Vicanolo, T., Özcan, A., Li, J. L., Huerta-López, C., Ballesteros, I., Rubio-Ponce, A., Dumitru, A.-C., Nicolás-Ávila, J. Á., Molina-Moreno, M., Reyes-Gutierrez, P., Johnston, A. D., Martone, C., Greto, E., Quílez-Alvarez, A., Calvo, E., Bonzon-Kulichenko, E., Álvarez-Velez, R., Chooi, M. Y., Kwok, I., et al. (2025). Matrix-producing neutrophils populate and shield the skin. Nature, 641(8063), 740-748. https://doi.org/10.1038/s41586-025-08741-5 (Original work published 2025)

Pricolo, M. R., López-Unzu, M. A., Vicente, N., Morales-López, C., Huerta-López, C., Pérez-Franco, W., Dumitru, A.-C., Espinosa, F. M., Sanchez, M. I., Garcia, R., Silva-Rojas, R., Herrero-Galán, E., Alegre-Cebollada, J., & et al. (2025). Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation. Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation, 1(1), 1. https://doi.org/10.1101/2025.04.22.645658 (Original work published 2025)

Silva-Rojas, R., Vicente, N., Gavilán-Herrera, M., Labrador-Cantarero, V., Sicilia, J., Giménez-Sáez, O., Dumitru, A.-C., Sánchez, M. I., Gato-Vilaseca, M., Velázquez-Carreras, D., López, J. A., Vázquez, J., Herrero-Galán, E., López-Unzu, M. A., Pricolo, M. R., & Alegre-Cebollada, J. (2025). Mechanically knocking out titin reveals protein tension loss as a trigger of muscle disease. Nature Biomedical Engineering, 1(1), 1. https://doi.org/10.1038/s41551-025-01403-x (Original work published 2025)

Stommen, A., Ghodsi, M., Cloos, A.-S., Conrard, L., Dumitru, A.-C., Henriet, P., Pierreux, C., Alsteens, D., & Tyteca, D. (2024). Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte–Discocyte–Echinocyte Transformation. Biomolecules, 14(1), 51 [1-27]. https://doi.org/10.3390/biom14010051 (Original work published 2024)

dos Santos Natividade, R., Dumitru, A.-C., Nicoli, A., Strebl, M., Sutherland, D. M., Welsh, O. L., Ghulam, M., Stehle, T., Dermody, T. S., Di Pizio, A., Koehler, M., & Alsteens, D. (2024). Viral capsid structural assembly governs the reovirus binding interface to NgR1. Nanoscale Horizons : the home for rapid reports of exceptional significance in nanoscience and nanotechnology, 9(11), 1925-1937. https://doi.org/10.1039/d4nh00315b (Original work published 2024)

Dumitru, A.-C., Köhler, M., & et al. (2023). Recent advances in the application of atomic force microscopy to structural biology. Journal of Structural Biology, 2(215), 107963. https://doi.org/10.1016/j.jsb.2023.107963 (Original work published 2023)

Lo Giudice, M., Yang, J., Poncin, M. A., Adumeau, L., Delguste, M., Koehler, M., Evers, K., Dumitru, A.-C., Dawson, K. A., & Alsteens, D. (2022). Nanophysical Mapping of Inflammasome Activation by Nanoparticles via Specific Cell Surface Recognition Events. ACS Nano, 16(1), 306-316. https://doi.org/10.1021/acsnano.1c06301 (Original work published 2021)

Maja, M., Mohammed, D., Dumitru, A.-C., Verstraeten, S., Lingurski, M., Mingeot-Leclercq, M.-P., Alsteens, D., & Tyteca, D. (2022). Surface cholesterol-enriched domains specifically promote invasion of breast cancer cell lines by controlling invadopodia and extracellular matrix degradation. Cellular and Molecular Life Sciences, 79(8), 417 [1-20]. https://doi.org/10.1007/s00018-022-04426-8 (Original work published 2022)

Mohammed, D., Koehler, M., Dumitru, A.-C., Aravamudhan, P., Sutherland, D. M., Dermody, T. S., & Alsteens, D. (2021). Altered Glycan Expression on Breast Cancer Cells Facilitates Infection by T3 Seroptype Oncolytic Reovirus. Nano Letters : a journal dedicated to nanoscience and nanotechnology, 21(22), 9720-9728. https://doi.org/10.1021/acs.nanolett.1c03608 (Original work published 2021)

Koehler, M., Petitjean, S., Yang, J., Aravamudhan, P., Somoulay, X., Lo Giudice, M., Poncin, M., Dumitru, A.-C., Dermody, T. S., & Alsteens, D. (2021). Reovirus directly engages integrin to recruit clathrin for entry into host cells. Nature Communications, 12(1), 1-15. https://doi.org/10.1038/s41467-021-22380-0 (Original work published 2021)

Cloos, A.-S., Daenen, L. G. M., Maja, M., Stommen, A., Vanderroost, J., Van Der Smissen, P., Rab, M., Westerink, J., Mignolet, E., Larondelle, Y., Terrasi, R., Muccioli, G., Dumitru, A.-C., Alsteens, D., van Wijk, R., & Tyteca, D. (2021). Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia – A Case Study. Frontiers in Physiology, 12(2), 638027 [1-22]. https://doi.org/10.3389/fphys.2021.638027 (Original work published 2021)

Koehler, M., Petitjean, S., Yang, J., Aravamudhan, P., Somoulay, X., Lo Giudice, M., Poncin, M., Dumitru, A.-C., Dermody, T. S., & Alsteens, D. (2021). Author Correction: Reovirus directly engages integrin to recruit clathrin for entry into host cells. Nature Communications, 12(1), 2946. https://doi.org/10.1038/s41467-021-23537-7 (Original work published 2021)

Müller, D. J., Dumitru, A.-C., Lo Giudice, M., Gaub, H. E., Hinterdorfer, P., Hummer, G., De Yoreo, J. J., Dufrêne, Y., & Alsteens, D. (2021). Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems. Chemical Reviews, 121, 11701-11725. https://doi.org/10.1021/acs.chemrev.0c00617 (Original work published 2020)

Yang, J., Petitjean, S., Koehler, M., Zhang, Q., Dumitru, A.-C., Chen, W., Derclaye, S., Vincent, S. P., Soumillion, P., & Alsteens, D. (2021). Author Correction: Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor. Nature Communications, 12(1), 2996. https://doi.org/10.1038/s41467-021-23498-x (Original work published 2021)

Dumitru, A.-C., Stommen, A., Koehler, M., Cloos, A.-S., Yang, J., Leclercqz, A., Tyteca, D., & Alsteens, D. (2021). Probing PIEZO1 Localization upon Activation Using High-Resolution Atomic Force and Confocal Microscopy. Nano Letters : a journal dedicated to nanoscience and nanotechnology, 21(12), 4950-4958. https://doi.org/10.1021/acs.nanolett.1c00599 (Original work published 2021)

Lecordier, L., Uzureau, S., Vanwalleghem, G., Deleu, M., Crowet, J.-M., Barry, P., Moran, B., Voorheis, P., Dumitru, A.-C., Yamaryo-Botté, Y., Dieu, M., Tebabi, P., Vanhollebeke, B., Lins, L., Botté, C. Y., Alsteens, D., Dufrêne, Y., Pérez-Morga, D., Nolan, D. P., & Pays, E. (2020). The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity. iScience, 23(9), 101476. https://doi.org/10.1016/j.isci.2020.101476 (Original work published 2020)

Dumitru, A.-C., Deepak, R. N. V. K., Liu, H., Koehler, M., Zhang, C., Fan, H., & Alsteens, D. (2020). Submolecular probing of the complement C5a receptor–ligand binding reveals a cooperative two-site binding mechanism. Communications Biology, 3(1), 786. https://doi.org/10.1038/s42003-020-01518-8 (Original work published 2020)

Valotteau, C., Dumitru, A.-C., Lecordier, L., Alsteens, D., Pays, E., Pérez-Morga, D., & Dufrêne, Y. (2020). Multiparametric Atomic Force Microscopy Identifies Multiple Structural and Physical Heterogeneities on the Surface of Trypanosoma brucei. ACS Omega, 5(33), 20953-20959. https://doi.org/10.1021/acsomega.0c02416 (Original work published 2020)

Yang, J., Petitjean, S., Koehler, M., Zhang, Q., Dumitru, A.-C., Chen, W., Derclaye, S., Vincent, S. P., Soumillion, P., & Alsteens, D. (2020). Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor. Nature Communications, 11(1), 4541. https://doi.org/10.1038/s41467-020-18319-6 (Original work published 2020)

Dumitru, A.-C., Mohammed, D., Maja, M., Yang, J., Verstraeten, S., del Campo, A., Mingeot-Leclercq, M.-P., Tyteca, D., & Alsteens, D. (2020). Label‐Free Imaging of Cholesterol Assemblies Reveals Hidden Nanomechanics of Breast Cancer Cells. Advanced Science, 2002643. https://doi.org/10.1002/advs.202002643 (Original work published 2020)